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HEL-3050: Clinical epidemiology and decision analysis Work Load 10 credits (ECTS) | Type of course Theoretical and practical. | Level of course/Year of study First or second year at master''s level. | Language of instruction Norwegian | Examination semester Spring | Objectives Having completed this course, the students will be able to assess and apply medical tests for diagnostic and therapeutic purposes. They should take a rational stance towards the ambiguity of medical decisions, and aim for a critical approach to medical documentation. | Contents The course provides an introduction to decision analysis applied to medical questions. Topics will be probability calculation, the concept of normality, the technical properties of tests, test properties and diagnostic properties. Problems regarding multi-testing and mutual dependency of tests are discussed as well as inter-observer and intra-observer agreements. Kappa statistics are explained and likelihood ratio is applied on strata of the separator variable. Optimal test values and the effect of case-mix on test properties are discussed. Furthermore, the course discusses documentation basis and various methods for evaluating medical intervention. Various approaches to systematic reviews of medical documentation will also be presented. The students will practice on medical Internet databases such as the Cochrane Library. | Form of teaching To a large extent, teaching will throug the Learning Management System ClassFronter. Three gatherings on campus, where teachers and students attend will be organized. Each gathering lasts for 2 or 3 days. Teaching will take the form of lectures, group work and seminars, and demand a large degree of activity and participation from the students. During the periods between gatherings, the students will be working via ClassFronter on text book material or evaluating articles and solving tasks. Discussion groups will be organised and to each of them, a teacher will be assigned. Much of the syllabus will be distributed to the students by their teachers over the Internet. Some material must be searched for by the students themselves, for instance in medical databases. | Exam and assessment At the end of the course students will work on a written home assignment. In addition, two home assignments will be given during the period between the gatherings, assignments which the students must hand in within given deadlines and must pass in order to continue the course. The home assignments may demand that a task be solved by means of calculation and assessment of the results, or that literature be assessed, or an essay must be written. The students will be given a grade (A-F) and concise written feedback about their written assignments. Moreover, active participation in discussion groups is required in the intervening period. All assignments are considered part of the exam and need to be answered individually. A single grade (A-F) will be given for the entire course on basis of the submitted three home assignments, for which an estimate of the extent and complexity of the undertaken tasks will be taken into consideration. | Contact person/lecturer Student Adviser Jorunn S. Myklebust, phone: +47 77644824. | Recommended reading/syllabus Pensumbok: David L. Sacket, R. Brian Haynes, Gordon H. Guyatt, Peter Tugwell: Clinical epidemiology. A basic science for clinical medicine. Little, Brown and Company, 1991, second edition, 441 sider. ISBN 0-316-76599-6
Boka viser hvordan prinsipper fra epidemiologi og biostatistikk kan brukes på komplekse kliniske beslutninger. Boka er bygget opp i logiske og skrittvise sekvenser. Velskrevet tekst, god pedagogikk.
Anbefalt litteratur:
Arild Bjørndal, Signe Flottorp, Atle Klovning: Medisinsk kunnskapshåndtering. Gyldendal Akademisk , 2000, 178 sider. ISBN 82-417-1062-3.
Boka gjør det lettere å handtere flommen av medisinsk kunnskap. Den viser hvordan man kan finne pålitelig kunnskap, og kritisk vurdere forskningsmetoder og -resultater. Forfatterne viser hvordan man implementerer ny kunnskap i klinisk og samfunnsmedisinsk praksis.
David L. Sacket, W Scott Richardson, William Rosenberg, R. Brian Haynes: Evidence-based Medicine. How to practice and teach EBM. Churchill Livingstone,1997, 250 sider. ISBN 0-443-05686-2.
Boka handler om hvordan individuell klinisk ekspertise kan integreres med den beste tilgjengelige eksterne kunnskap. Den tar utgangspunkt i det praktiske liv, og søker å fremme bruk av ?evidence-based medicine? i daglig virksomhet. Teksten omhandler klinisk epidemiologi og kritisk lesing av informasjon.
Myriam Hunink, Paul Glasziou, Joanna Siegel, Jane Weeks, Joseph Pliskin, Arthur Elstein, Milton Weinstein: Decision making in health and medicine. Integrating evidence and values. Cambrige University Press, 2003, 388 sider, ISBN 0-521-77029-7.
Boka gir en innføring i metoder som gir hjelp til å navigere gjennom diagnostiske og terapeutiske usikkerheter, pasientpreferanser og ?verdier, og kostnader. Metodene integrerer kvantitative kunnskapsbaserte data og subjektive pasientverdier, og de gir verdifull støtte ved medisinske og helsepolitiske beslutninger. Noe av teksten ligger på et relativt avansert nivå.
| Homepage http://uit.no/medfak-studietilbud/folkehelsevitensk/
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Teaching spring 2006 Tre obligatoriske samlinger a 3, 2 og 3 dgr uke 4: ons 25.-fre 27. jan uke 13: tor 30. og fre 31. mars uke 22: ons 31.mai - fre 2. juni Siste Hjemmeoppgave/eksamen innlevering fredag 9. juni (uke 23)
Oppstart uke 4: Onsd 25.jan kl. 1015, ISM, MH-bygget, ISM, rom L11.233 |
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