Nobelprisen i Medisin og Fysiologi for 2006
21.11.2006
Årets nobelpris i medisin og fysiologi er delt mellom Andrew Z. Fire og Craig C. Mello, begge fra USA, for deres oppdagelse av "RNA interference - gene silencing by double-stranded RNA"
Andrew Z. Fire Andrew Z. Fire er født i 1959 i USA. Han er tilknyttet Stanford Universty School of Medicine. Han har blant annet skrevet: Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference Hum-Mol-Genet. 2002 Jan 15; 11(2): 175-84 Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference. Mol-Biol-Cell. 2003 Jul; 14(7): 2972-83 The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 1999 (99)2: 123-32 Craig C. Mello Craig C. Mello er født i USA i 1960. Han er tilknyttet University of Massachusetts Medical SchoolWorcester, MA, USA. Han har blant annet skrevet: Sequence-specific inhibition of small RNA function. PLoS-Biol. 2004 Apr; 2(4): E98 Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature. 2005 Jul 28; 436(7050): 593-7 RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans. Nucleic-Acids-Res. 2005; 33(1): 347-55
Andrew Z. Fire Andrew Z. Fire er født i 1959 i USA. Han er tilknyttet Stanford Universty School of Medicine.
Han har blant annet skrevet:
Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference Hum-Mol-Genet. 2002 Jan 15; 11(2): 175-84
Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference. Mol-Biol-Cell. 2003 Jul; 14(7): 2972-83
The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 1999 (99)2: 123-32
Craig C. Mello Craig C. Mello er født i USA i 1960. Han er tilknyttet University of Massachusetts Medical SchoolWorcester, MA, USA.
Sequence-specific inhibition of small RNA function. PLoS-Biol. 2004 Apr; 2(4): E98
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature. 2005 Jul 28; 436(7050): 593-7
RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans. Nucleic-Acids-Res. 2005; 33(1): 347-55
