Eystein Sverre Husebye's picture
Eystein Sverre
Husebye
Head of Department
Visit Address: 
Haukeland universitetssykehus, Laboratoriebygget
5021 Bergen
Postal Address: 
Postboks 7804
5021 Bergen
Phone: 
+47 55 97 30 78
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Addison's disease

Autoimmune polyendocrine disorders

Hypoparathyroidism

Endocrinology

Journal articles
  • Bjånesøy, Trine Elholm; Kulle, Bettina; Bratland, Eirik; Reiner, Andrew Henry; Islam, Shahinul; Husebye, Eystein Sverre; Bakke, Marit. 2014. Altered DNA methylation profile in Norwegian patients with Autoimmune Addison's Disease. Molecular Immunology. 59: 208-216. doi: 10.1016/j.molimm.2014.02.018
  • Breivik, Lars Ertesvåg; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Orlova, Elizaveta M.; Husebye, Eystein Sverre. 2014. A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1. Clinical Immunology. 153: 220-227. doi: 10.1016/j.clim.2014.04.013
  • Hegvik, Tor-Arne; Husebye, Eystein Sverre; Haavik, Jan. 2014. Autoantibodies targeting neurotransmitter biosynthetic enzymes in attention-deficit/hyperactivity disorder (ADHD). European Child and Adolescent Psychiatry. 23: 115-117. doi: 10.1007/s00787-013-0429-3
  • Hellesen, Richard Alexander; Edvardsen, Kine Susann Waade; Breivik, Lars Ertesvåg; Husebye, Eystein Sverre; Bratland, Eirik. 2014. The effect of types I and III interferons on adrenocortical cells and its possible implications for autoimmune Addison's disease. Clinical and Experimental Immunology. 176: 351-362. doi: 10.1111/cei.12291
  • Husebye, Eystein Sverre; Allolio, Bruno; Arlt, Wiebke; Badenhoop, Klaus; Bensing, Sophie; Betterle, Corrado; Falorni, Alberto; Gan, Earn H.; Hulting, Anna-Lena; Kasperlik-Zaluska, Anna A.; Kämpe, Olle; Løvås, Kristian; Meyer, Gesine; Pearce, Simon H. 2014. Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency. Journal of Internal Medicine. 275: 104-115. doi: 10.1111/joim.12162
  • Mitchell, Anna L.; Macarthur, Katie D.R.; Gan, Earn H.; Baggott, Lucy E.; Wolff, Anette Susanne Bøe; Skinningsrud, Beate; Platt, Hazel; Short, Andrea; Lobell, Anna; Kämpe, Olle; Bensing, Sophie; Betterle, Corrado; Kasperlik-Zaluska, Anna; Zurawek, Magdalena; Fichna, Marta; Kockum, Ingrid; Eriksson, Gabriel Nordling; Ekwall, Olov; Wahlberg, Jeanette; Dahlqvist, Per; Hulting, Anna-Lena; Penna-Martinez, Marissa; Meyer, Gesine; Kahles, Heinrich; Badenhoop, Klaus; Hahner, Stefanie; Quinkler, Marcus; Falorni, Alberto; Phipps-Green, Amanda; Merriman, Tony R.; Ollier, William; Cordell, Heather J.; Undlien, Dag Erik; Czarnocka, Barbara; Husebye, Eystein Sverre; Pearce, Simon H.S. 2014. Association of autoimmune Addison's disease with alleles of STAT4 and GATA3 in European Cohorts. PLoS ONE. 9. doi: 10.1371/journal.pone.0088991
  • Øksnes, Marianne; Björnsdottir, Sigridur; Isaksson, Magnus; Methlie, Paal; Carlsen, Siri; Nilsen, Roy Miodini; Broman, Jan-Erik; Triebner, Kai; Kämpe, Olle; Hulting, Anna-Lena; Bensing, Sophie; Husebye, Eystein Sverre; Løvås, Kristian. 2014. Continuous subcutaneous hydrocortisone infusion versus oral hydrocortisone replacement for treatment of Addison's disease: A randomized clinical trial. Journal of Clinical Endocrinology and Metabolism. 99: 1665-1674. doi: 10.1210/jc.2013-4253
  • Bratland, Eirik; Hellesen, Alexander; Husebye, Eystein Sverre. 2013. Induction of CXCL10 chemokine in adrenocortical cells by stimulation through toll-like receptor 3. Molecular and Cellular Endocrinology. 365: 75-83. doi: 10.1016/j.mce.2012.09.004
  • Bratland, Eirik; Magitta, Ng'weina Francis; Wolff, Anette Susanne Bøe; Ekern, Trude; Knappskog, Per; Kämpe, Olle; Haavik, Jan; Husebye, Eystein Sverre. 2013. Autoantibodies against aromatic amino acid hydroxylases in patients with autoimmune polyendocrine syndrome type 1 target multiple antigenic determinants and reveal regulatory regions crucial for enzymatic activity. Immunobiology. 218: 899-909. doi: 10.1016/j.imbio.2012.10.006
  • Brønstad, Ingeborg; Skinningsrud, Beate; Wolff, Anette Susanne Bøe; Bratland, Eirik; Løvås, Kristian; Knappskog, Per; Undlien, Dag Erik; Husebye, Eystein Sverre. 2013. Characterisation of the CYP21A2 Gene in Patients with Autoimmune Addison's Disease. Scandinavian Journal of Immunology. 77: 310-310.
  • Horn, Morten Andreas; Erichsen, Martina Moter; Wolff, Anette Susanne Bøe; Månsson, Jan-Eric; Husebye, Eystein Sverre; Tallaksen, Chantal; Skjeldal, Ola. 2013. Screening for X-linked adrenoleukodystrophy among adult men with Addison's disease. Clinical Endocrinology. 79: 316-320. doi: 10.1111/cen.12159
  • Kärner, Jaanika; Meager, Anthony; Laan, Maris; Maslovskaja, Julia; Pihlap, Maire; Remm, Anu; Juronen, Erkki; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Podkrajšek, Katarina Trebušak; Bratanic, Nina; Battelino, Tadej; Willcox, Nicholas; Peterson, Pärt; Kisand, Kai. 2013. Anti-cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice. Clinical and Experimental Immunology. 171: 263-272. doi: 10.1111/cei.12024
  • Massey, Jonathan; Boag, Alisdair; Short, Andrea D.; Scholey, Rachel A.; Henthorn, Paula S.; Littman, Meryl P.; Husebye, Eystein Sverre; Catchpole, Brian; Pedersen, Niels; Mellersh, Cathryn S.; Ollier, William E.R.; Kennedy, Lorna J. 2013. MHC class II association study in eight breeds of dog with hypoadrenocorticism. Immunogenetics. 65: 291-297. doi: 10.1007/s00251-013-0680-2
  • Oftedal, Bergithe Eikeland; Erichsen, Martina Moter; Hellesen, Alexander; Perheentupa, Jaako; Fiskarstrand, Torunn; Knappskog, Per; Abramson, Jakub; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2013. Dominant Inheritance in Autoimmune Endocrine Syndrome Type 1. Scandinavian Journal of Immunology. 77: 306-307.
  • Penna-Martinez, Marissa; Schwartz, Julia M.; Shoghi, Faroquhi; Meyer, Gesine; Wolff, Anette Susanne Bøe; Hahner, Stefanie; Willenberg, Holger S.; Reisch, Nicole; Quinkler, Marcus; Seidl, Christian; Husebye, Eystein Sverre; Badenhoop, Klaus. 2013. Human leukocyte antigen (DQ2/DQ8) and 21-hydroxylase antibodies determine the thyroid peroxidase antibody status of patients in autoimmune Addison's disease. Experimental and clinical endocrinology & diabetes. 121. 2 pages. doi: 10.1055/s-0033-1336696
  • Short, Andrea D.; Boag, Alisdair; Catchpole, Brian; Kennedy, Lorna J.; Massey, Jonathan; Rothwell, Simon; Husebye, Eystein Sverre; Ollier, Bill. 2013. A candidate gene analysis of canine hypoadrenocorticism in 3 dog breeds. Journal of Heredity. 104: 807-820. doi: 10.1093/jhered/est051
  • Shum, Anthony K.; Alimohammadi, Mohammad; Tan, Catherie L.; Cheng, Mickie H.; Metzger, Todd C.; Law, Christopher S.; Lwin, Wint; Perheentupa, Jaakko; Bour-Jordan, Helene; Carel, Jean-Claude; Husebye, Eystein Sverre; De Luca, Filippo; Janson, Christer; Sargur, Ravishankar; Dubois, Noémie; Kajosaari, Merja; Wolters, Paul J.; Chapman, Harold A.; Kämpe, Olle; Anderson, Mark S. 2013. BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease. Science Translational Medicine. 5. 10 pages. doi: 10.1126/scitranslmed.3006998
  • Wolff, Anette Susanne Bøe; Sarkadi, Adrien Katalin; Maródi, László; Kärner, Jaanika; Orlova, Elizaveta; Oftedal, Bergithe Eikeland; Kisand, Kai; Ólah, Éva; Meloni, Antonella; Myhre, Anne Grethe; Husebye, Eystein Sverre; Motaghedi, Roja; Perheentupa, Jaako; Peterson, Pärt; Willcox, Nick; Meager, Anthony. 2013. Anti-cytokine autoantibodies preceding onset of autoimmune polyendocrine syndrome type I features in early childhood. Journal of Clinical Immunology. 33: 1341-1348. doi: 10.1007/s10875-013-9938-6
  • Bratland, Eirik; Hellesen, Richard Alexander; Husebye, Eystein Sverre. 2012. Mice deficient for the autoimmune regulator, Aire, display altered T cell responses against 21-hydroxylase, the major autoantigen in autoimmune Addison's disease. Immunology. 137: 542-542. doi: 10.1111/imm.12002
  • Hapnes, Liv; Willcox, Nick; Oftedal, Bergithe Eikeland; Owe, Jone Furulund; Gilhus, Nils Erik; Meager, Anthony; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2012. Radioligand-binding assay reveals distinct autoantibody preferences for type I interferons in APS I and myasthenia gravis subgroups. Journal of Clinical Immunology. 32: 230-237. doi: 10.1007/s10875-011-9617-4
  • Hellesen, A; Bratland, Eirik; Husebye, Eystein Sverre. 2012. Poly (I:C)-induced CXCL10 production in adrenocortical cells - implications for autoimmune Addison's disease? Immunology. 137: 300-301.
  • Husebye, Eystein Sverre. 2012. E. S. Husebye svarer. Tidsskrift for Den norske legeforening. 124: 2475.
  • Husebye, Eystein Sverre; Ericksen, Martina; Myhre, A-G; Bratke, H; Jørgensen, AP; Dahlqvist, P; Løvås, Kristian. 2012. Nytt steroidkort ved binyrebarksvikt. Tidsskrift for Den norske legeforening. 132: 2043-2044.
  • Meloni, Antonella; Willcox, Nick; Meager, Anthony; Atzeni, Michela; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Furcas, Maria; Rosatelli, Maria Cristina; Cao, Antonio; Congia, Mauro. 2012. Autoimmune polyendocrine syndrome Type 1: an Eetensive longitudinal study in Sardinian patients. Journal of Clinical Endocrinology and Metabolism. 97: 1114-1124. doi: 10.1210/jc.2011-2461
  • Nermoen, Ingrid; Brønstad, Ingeborg; Fougner, Kristian J; Svartberg, Johan; Øksnes, Marianne; Husebye, Eystein Sverre; Løvås, Kristian. 2012. Genetic, anthropometric and metabolic features of adult Norwegian patients with 21-hydroxylase deficiency. European Journal of Endocrinology. 167: 507-516. doi: 10.1530/EJE-12-0196
  • Oftedal, B.E.V.; Meager, A; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2012. Measuring autoantibodies against IL-17F and IL-22 in autoimmune polyedocrine sydnrome type I. Immunology. 137: 673-674.
  • Wolff, Anette Susanne Bøe; Ostre, A.; Oftedal, Bergithe Eikeland; Husebye, Eystein Sverre. 2012. Deviant expression of defensins in sera and saliva of patients with autoimmune polyendocrine syndrome type I. Immunology. 137: 211-212.
  • Øksnes, Marianne; Bensing, Sophie; Hulting, Anna-Lena; Kämpe, Olle; Hackemann, Annika; Meyer, Gesine; Badenhoop, Klaus; Betterle, Corrado; Parolo, Anna; Giordano, Roberta; Falorni, Alberto; Papierska, Lucyna; Jeske, Wojciech; Kasperlik-Zaluska, Anna A.; Chatterjee, V. Krishna K.; Husebye, Eystein Sverre; Løvås, Kristian. 2012. Quality of life in European patients with Addison's Disease: Validity of the disease-specific questionnaire AddiQoL. Journal of Clinical Endocrinology and Metabolism. 97: 568-576. doi: 10.1210/jc.2011-1901
  • Bratland, Eirik; Husebye, Eystein Sverre. 2011. Cellular immunity and immunopathology in autoimmune Addison’s disease. Molecular and Cellular Endocrinology. 336: 180-190. doi: 10.1016/j.mce.2010.12.015
  • Brønstad, Ingeborg; Wolff, Anette Susanne Bøe; Løvås, Kristian; Knappskog, Per; Husebye, Eystein Sverre. 2011. Genome-wide copy number variation (CNV) in patients with autoimmune Addison's disease. BMC Medical Genetics. 12. 6 pages. doi: 10.1186/1471-2350-12-111
  • Cuida Marthinussen, Ileana Mihaela; Erichsen, Martina Moter; Jonsson, Malin V; Altenau, Anne Chr.; Husebye, Eystein Sverre. 2011. Oral manifestations of autoimmune polyendocrine syndrome type I. Caries Research. 45: 186-187. doi: 10.1159/000328514
  • Hellesen, Richard Alexander; Bratland, Eirik; Husebye, Eystein Sverre. 2011. Endogenous Production of CXC Chemokine Ligand 10 (CXCL10) by Adrenocortical Cells and its Implications for Autoimmune Addison's Disease. Scandinavian Journal of Immunology. 73: 371-371.
  • Lima, Kari; Abrahamsen, Tore G; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Alimohammadi, Mohammad; Kämpe, Olle; Følling, Ivar. 2011. Hypoparathyroidism and autoimmunity in the 22q11.2 deletion syndrome. European Journal of Endocrinology. 165: 345-352. doi: 10.1530/EJE-10-1206
  • Methlie, Paal; Husebye, Eystein Sverre; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Løvås, Kristian. 2011. Grapefruit juice and licorice increase cortisol availability in patients with Addison's disease. European Journal of Endocrinology. 165: 761-769. doi: 10.1530/EJE-11-0518
  • Nermoen, Ingrid; Rørvik, Jarle; Holmedal, Stein Harald; Hykkerud, Dan L; Fougner, Kristian J; Svartberg, Johan; Husebye, Eystein Sverre; Løvås, Kristian. 2011. High frequency of adrenal myelolipomas and testicular adrenal rest tumours in adult Norwegian patients with classical congenital adrenal hyperplasia because of 21-hydroxylase deficiency. Clinical Endocrinology. 75: 753-759. doi: 10.1111/j.1365-2265.2011.04151.x
  • Oftedal, Bergithe Eikeland; Kämpe, Olle; Meager, Anthony; Ahlgren, Kerstin M.; Lobell, Anna; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2011. Measuring autoantibodies against IL-17F and IL-22 in Autoimmune Polyendocrine Syndrome Type I by radioligand binding assay using fusion proteins. Scandinavian Journal of Immunology. 74: 327-333. doi: 10.1111/j.1365-3083.2011.02573.x
  • Skinningsrud, Beate; Lie, Benedicte Alexandra; Lavant, Ewa; Carlson, Joyce A.; Erlich, Henry; Akselsen, Hanne Elisabeth; Gervin, Kristina; Wolff, Anette Susanne Bøe; Erichsen, Eva Martina Moter; Løvås, Kristian; Husebye, Eystein Sverre; Undlien, Dag Erik. 2011. Multiple loci in the HLA complex are associated with Addison's Disease. Journal of Clinical Endocrinology and Metabolism. 96: E1703-E1708. doi: 10.1210/jc.2011-0645
  • Smith, Casey J.A.; Oscarson, Mikael; Rönnblom, Lars; Alimohammadi, Mohammad; Perheentupa, Jaako; Husebye, Eystein Sverre; Gustafsson, Jan; Nordmark, Gunnel; Meloni, Antonella; Crock, Patricia A.; Kämpe, Olle; Bensing, Sophie. 2011. TSGA10 – A target for autoantibodies in autoimmune polyendocrine syndrome Type 1 and systemic lupus erythematosus. Scandinavian Journal of Immunology. 73: 147-153. doi: 10.1111/j.1365-3083.2010.02486.x
  • Wolff, Anette Susanne Bøe; Kisand, Kai; Meager, Anthony; Willcox, Nick; Peterson, Part; Husebye, Eystein Sverre. 2011. Cytokine Antibodies in Autoimmune Polyendocrine Syndrome Type I Correlates to Chronic candidiasis. Scandinavian Journal of Immunology. 73: 379-379.
  • Bratland, Eirik; Husebye, Eystein Sverre. 2010. The Possible Roles of Interferon-Gamma, CXC Chemokine Ligand 10 (CXCL10) and the CXCR3 Circuit in the Pathogenesis of Autoimmune Addison's Disease. Scandinavian Journal of Immunology. 71: 479-480.
  • Cheng, M; Fan, U; Grewal, N; Barnes, M; Mehta, A; Taylor, S; Husebye, Eystein Sverre; Murphy, EJ; Anderson, MS. 2010. Acquired Autoimmune Polyglandular Syndrome, Thymoma, and an AIRE Defect. New England Journal of Medicine. 362: 764-766.
  • Erichsen, Eva Martina Moter; Husebye, Eystein Sverre; Michelsen, Trond Melbye; Dahl, Alv A; Løvås, Kristian. 2010. Sexuality and Fertility in Women with Addison's Disease. Journal of Clinical Endocrinology and Metabolism. 95: 4354-4360. doi: 10.1210/jc.2010-0445
  • Erichsen, Martina M.; Husebye, Eystein Sverre; Dahl, Alv A; Løvås, Kristian. 2010. Sexuality, Fertility and Androgens in Women with Addison's Disease. Endocrine reviews. 31: 3.
  • Hallgren, Åsa; Pourmousa, Mina; Skov, Jakob; Nilsson, Thomas; Gustafsson, Jan; Husebye, Eystein Sverre; Perheentupa, Jaako; Hagforsen, Eva; Rorsman, Fredrik; Kämpe, Olle. 2010. Immunoreactivity against kidney collecting ducts in patients with autoimmune polyendocrine syndrome type 1 and systemic hypertension. Endocrine journal. 57: S641-S641.
  • Husebye, Eystein Sverre; Anderson, Mark S. 2010. Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis. Immunity. 32: 479-487. doi: 10.1016/j.immuni.2010.03.016
  • Kisand, Kai; Wolff, Anette Susanne Bøe; Podkrajsek, Katarina Trebusak; Tserel, Liina; Link, Maire; Kisand, Kalle V.; Ersvær, Elisabeth; Perheentupa, Jaakko; Bratanic, Nina; Meloni, Antonella; Cetani, Filomena; Perniola, Roberto; Ergun-Longmire, Berrin; Maclaren, Noel K.; Krohn, Kai J.E.; Pura, Mikulás; Schalke, Berthold; Ströbel, Philipp; Leite, Maria Isabel; Battelino, Tadej; Husebye, Eystein Sverre; Peterson, Pärt; Willcox, Nick; Meager, Anthony; Erichsen, Eva Martina Moter. 2010. Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. Journal of Experimental Medicine. 207: 299-308. doi: 10.1084/jem.20091669
  • Løvås, Kristian; Curran, Suzanne; Øksnes, Marianne; Husebye, Eystein Sverre; Huppert, Felicia A.; Chatterjee, V. Krishna K. 2010. Development of a Disease-Specific Quality of Life Questionnaire in Addison's Disease. Journal of Clinical Endocrinology and Metabolism. 95: 545-551. doi: 10.1210/jc.2009-1711
  • Methlie, Paal; Løvås, Kristian; Lien, Ernst Asbjørn; Husebye, Eystein Sverre. 2010. Grapefruit and Liquorice Increase Bioavailable Cortisol in Addison's Disease. Endocrine reviews. 31. 1 pages.
  • Nermoen, Ingrid; Husebye, Eystein; Svartberg, Johan; Løvås, K. 2010. Subjective health status in men and women with congenital adrenal hyperplasia: a population-based survey in Norway. European Journal of Endocrinology. 163: 453-459. doi: 10.1530/EJE-10-0284
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Kämpe, Olle; Husebye, Eystein Sverre. 2010. Nucleoporin 62, a Novel Autoantigen in Patients with Autoimmune Polyendocrine Syndrome Type I (APS I). Scandinavian Journal of Immunology. 71: 493-494.
  • Skinningsrud, Beate; Lie, Benedicte; Husebye, Eystein S; Kvien, Tore K; Førre, Øystein; Flatø, Berit; Stormyr, Alice; Joner, Geir; Njølstad, Pål R; Egeland, Thore; Undlien, Dag E. 2010. A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis. Annals of the Rheumatic Diseases. 69: 1471-1474. doi: 10.1136/ard.2009.114934
  • Sørheim, Jan Inge; Husebye, Eystein Sverre; Nedrebø, Bjørn Gunnar; Svarstad, Einar; Lind, Jonas Anders; Boman, Helge; Løvås, Kristian. 2010. Phenotypic Variation in a Large Family with Autosomal Dominant Hypocalcaemia. Hypertension in Pregnancy. 74: 399-405. doi: 10.1159/000303188
  • Toth, Beata; Wolff, Anette Susanne Bøe; Halász, Zita; Tar, Attila; Szüts, Péter; Ilyés, István; Erdős, Melinda; Szegedi, Gyula; Husebye, Eystein Sverre; Zeher, Margit; Maródi, László. 2010. Novel sequence variation of AIRE and detection of interferon-ω antibodies in early infancy. Clinical Endocrinology. 72: 641-647. doi: 10.1111/j.1365-2265.2009.03740.x
  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Kisand, Kai; Ersvær, Elisabeth; Lima, Kari; Husebye, Eystein Sverre. 2010. Flow cytometry study of blood cell subtypes reflects autoimmune and inflammatory processes in autoimmune polyendocrine syndrome type I. Scandinavian Journal of Immunology. 71: 459-467. doi: 10.1111/j.1365-3083.2010.02397.x
  • Alimohammadi, Mohammad; Dubois, Noémie; Sköldberg, Filip; Hallgren, Åsa; Tardivel, Isabelle; Hedstrand, Håkan; Haavik, Jan; Husebye, Eystein Sverre; Gustafsson, Jan; Rorsman, Fredrik; Meloni, Antonella; Janson, Christer; Vialettes, Bernard; Kajosaari, Merja; Egner, William; Sargur, Ravishankar; Pontén, Fredrik; Amoura, Zahir; Grimfeld, Alain; De Luca, Filippo; Betterle, Corrado; Perheentupa, Jaakko; Kämpe, Olle; Carel, Jean-Claude. 2009. Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen. Proceedings of the National Academy of Science of the United States of America. 106: 4396-4411. doi: 10.1073/pnas.0809986106
  • Bratland, Eirik; Bredholt, Geir; Mellgren, Gunnar; Knappskog, Per; Mozes, Edna; Husebye, Eystein Sverre. 2009. The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: The major autoantigen in autoimmune Addison's disease. Journal of Autoimmunity. 33: 58-67. doi: 10.1016/j.jaut.2009.02.018
  • Bratland, Eirik; Skinningsrud, B; Undlien, Dag Erik; Mozes, Edna; Husebye, Eystein Sverre. 2009. T Cell Responses to Steroid Cytochrome P450 21-Hydroxylase in Patients with Autoimmune Primary Adrenal Insufficiency. Journal of Clinical Endocrinology and Metabolism. 94: 5117-5124. doi: 10.1210/jc.2009-1115
  • Cheng, M; Barnes, M; Mehta, A; Taylor, S; Murphy, E; Zhang, L; Husebye, Eystein Sverre; Eisenbarth, G; Anderson, M. 2009. Loss of AIRE Expression in Thymoma Tissue Associated with Multiple Endocrine Autoimmunity: A Novel Case of APS1. Clinical Immunology. 131: S128-S128. doi: 10.1016/j.clim.2009.03.378
  • Erichsen, Martina Moter; Erichsen, Martina M; Lovas, K; Løvås, Kristian; Fougner, Kristian J; Svartberg, Johan; Hauge, Erik R; Bollerslev, Jens; Berg, Jens P; Mella, Bjarne; Husebye, Eystein S. 2009. Normal overall mortality rate in Addison's disease, but young patients are at risk of premature death. European Journal of Endocrinology. 160: 233-237. doi: 10.1530/EJE-08-0550
  • Erichsen, Martina Moter; Erichsen, Martina M; Løvås, Kristian; Skinningsrud, Beate; Wolff, Anette; Undlien, Dag E; Svartberg, Johan; Fougner, Kristian J; Berg, Tore J.; Bollerslev, Jens; Mella, Bjarne; Mella, Bjarne; Carlson, Joyce A; Erlich, Henry; Ehrlich, H; Husebye, Eystein S. 2009. Clinical, Immunological, and Genetic Features of Autoimmune Primary Adrenal Insufficiency: Observations from a Norwegian Registry. Journal of Clinical Endocrinology and Metabolism. 94: 4882-4890. doi: 10.1210/jc.2009-1368
  • Fetissov, Sergueï O.; Bensing, Sophie; Mulder, Jan; Le Maitre, Erwan; Hulting, Anna-Lena; Harkany, Tibor; Ekwall, Olov; Sköldberg, Filip; Husebye, Eystein Sverre; Perheentupa, Jaakko; Rorsman, Fredrik; Kämpe, Olle; Hökfelt, Tomas. 2009. Autoantibodies in autoimmune polyglandular syndrome type I patients react with major brain neurotransmitter systems. Journal of Comparative Neurology. 513: 1-20. doi: 10.1002/cne.21913
  • Husebye, Eystein Sverre. 2009. Editorial: Functional Autoantibodies Cause Hypoparathyroidism. Journal of Clinical Endocrinology and Metabolism. 94: 4655-4657. doi: 10.1210/jc.2009-2123
  • Husebye, Eystein Sverre. 2009. Functional autoantibodies cause hypoparathyroidism. Journal of Clinical Endocrinology and Metabolism. 94: 4655-4657.
  • Husebye, Eystein Sverre. 2009. Skin changes as diagnostic aid. Tidsskrift for Den norske legeforening. 129: 752-752. doi: 10.4045/tidsskr.09.0085
  • Husebye, Eystein Sverre; Løvås, Kristian. 2009. Immunology of Addison's Disease and premature ovarian failure. Endocrinology and metabolism clinics of North America (Print). 38: 389-405. doi: 10.1016/j.ecl.2009.01.010
  • Husebye, Eystein Sverre; Løvås, Kristian. 2009. Pathogenesis of primary adrenal insufficiency. Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism. 23: 147-157. doi: 10.1016/j.beem.2008.09.004
  • Husebye, Eystein Sverre; Perheentupa, Jaakko; Rautemaa, Riina; Kämpe, Olle. 2009. Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I. Journal of Internal Medicine. 265: 514-529. doi: 10.1111/j.1365-2796.2009.02090.x
  • Løvås, K; Wensaas, AJ; Røst, TH; Rustan, AC; Rokling-Andersen, MH; Skorve, Jon; Caesar, R; Ulvik, RJ; Jensen, J; Kaalhus, O; Bohov, P; Graff, Bjørn Anton; Gudbrandsen, OA; Berge, RK; Husebye, ES; Drevon, CA. 2009. Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets. Diabetes, obesity and metabolism. 11: 1034-1049. doi: 10.1111/j.1463-1326.2009.01092.x
  • Løvås, Kristian; Curran, Suzanne; Øksnes, Marianne; Husebye, Eystein Sverre; Huppert, Felicia A.; Chatterjee, V.K. 2009. Development of a Disease-Specific Quality of Life Questionnaire in Addison’s Disease. Journal of Clinical Endocrinology and Metabolism. Published 2009-12-16. doi: 10.1210/jc.2009-1711
  • Løvås, Kristian; Gjesdal, Clara G; Christensen, Monica; Wolff, Anette; Almas, B; Almås, Bjørg; Svartberg, Johan; Fougner, Kristian J; Syversen, Unni; Bollerslev, Jens; Falch, Jan A; Falch, Jan Arvid; Hunt, Penelope; Chatterjee, V Krishna; Husebye, Eystein S. 2009. Glucocorticoid replacement therapy and pharmacogenetics in Addison's disease: effects on bone. European Journal of Endocrinology. 160: 993-1002. doi: 10.1530/EJE-08-0880
  • Løvås, Kristian; Lovas, K; Røst, Therese Halvorsen; Rost, TH; Skorve, Jon; Ulvik, Rune Johan; Gudbrandsen, Oddrun Anita; Bohov, Pavol; Wensaas, Andreas J.; Rustan, Arild C.; Berge, Rolf Kristian; Husebye, Eystein Sverre. 2009. Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes, obesity and metabolism. 11: 304-314. doi: 10.1111/j.1463-1326.2008.00958.x
  • Magitta, Ng'weina Francis; Wolff, Anette Susanne Bøe; Johansson, Stefan; Skinningsrud, Beate; Lie, Benedicte A; Myhr, Kjell-Morten; Undlien, Dag Erik; Joner, Geir; Njølstad, Pål Rasmus; Kvien, Tore K.; Førre, Øystein; Knappskog, Per Morten; Husebye, Eystein Sverre. 2009. A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes. Genes and Immunity. 10: 120-124. doi: 10.1038/gene.2008.85
  • Mitchell, AL; Cordell, HJ; Soemedi, R; Owen, K; Skinningsrud, Beate; Wolff, AB; Ericksen, M; Undlien, Dag Erik; Husebye, Eystein; Pearce, SH. 2009. Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility. Journal of Clinical Endocrinology and Metabolism. 94: 5139-5145. doi: 10.1210/jc.2009-1404
  • Mitchell, Anna L.; Cordell, Heather J.; Soemedi, Rachel; Skinningsrud, Beate; Wolff, Anette Susanne Bøe; Ericksen, Martina; Undlien, Dag; Husebye, Eystein Sverre; Pearce, Simon H. 2009. Programmed Death Ligand 1 (PD-L1) Gene Variants Contribute to Autoimmune Addison’s Disease and Graves’ Disease Susceptibility. Journal of Clinical Endocrinology and Metabolism. 94: 5139-5145. doi: 10.1210/jc.2009-1404
  • Nermoen, Ingrid; Følling, Ivar; Vegge, Kjetil; Larmo, Arne; Nedrebø, Bjørn Gunnar; Husebye, Eystein Sverre; Løvås, Kristian. 2009. Two adults with adrenal myelolipoma and 21-hydroxylase deficiency. Clinical Medicine : Case Reports. 4 pages. Published 2009-08-13. doi: 10.1155/2009/916891
  • Skinningsrud, Beate; Husebye, Einar; Husebye, Eystein Sverre; Gilfillan, Gregor D; Frengen, Eirik; Erichsen, Aage; Gervin, Kristina; Gervin, Kristina; Ormerod, Eli; Ormerød, Eli; Egeland, Thore; Egeland, Thore; Undlien, Dag E. 2009. X-Linked Congenital Adrenal Hypoplasia with Hypogonadotropic Hypogonadism Caused by an Inversion Disrupting a Conserved Noncoding Element Upstream of the NR0B1 (DAX1) Gene. Journal of Clinical Endocrinology and Metabolism. 94: 4086-4093. doi: 10.1210/jc.2009-0923
  • Skinningsrud, Beate; Lie, Benedicte Alexandra; Husebye, Eystein; Kvien, TK; Førre, Øystein Thorleiv; Flatø, Berit; Stormyr, Alice; Joner, Geir; Njølstad, Pål R.; Egeland, Thore; Undlien, Dag Erik. 2009. A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-CCP negative rheumatoid arthritis. Annals of the Rheumatic Diseases. Published 2009-09-01. doi: 10.1136/ard.2009.114934
  • Aarhus, Mads; Bruland, Ove; Bredholt, Geir; Lybæk, Helle; Husebye, Eystein Sverre; Krossnes, Bård Kronen; Vedeler, Christian A.; Wester, Knut; Lund-Johansen, Morten; Knappskog, Per. 2008. Microarray analysis reveals down-regulation of the tumour suppressor gene WWOX and up-regulation of the oncogene TYMS in intracranial sporadic meningiomas. Journal of Neuro-Oncology. 88: 251-259. doi: 10.1007/s11060-008-9569-6
  • Alimohammadi, Mohammad; Björklund, Peyman; Hallgren, Åsa; Pöntynen, Nora; Szinnai, Gabor; Shikama, Noriko; Keller, Marcel P.; Ekwall, Olov; Kinkel, Sarah A.; Husebye, Eystein Sverre; Gustafsson, Jan; Rorsman, Fredrik; Peltonen, Leena; Betterle, Corrado; Perheentupa, Jaakko; Åkerström, Göran; Westin, Gunnar; Scott, Hamish S.; Holländer, Georg A.; Kämpe, Olle. 2008. Autoimmune polyendocrine syndrome type 1 and NALP5, parathyroid autoantigen. New England Journal of Medicine. 358: 1018-1028.
  • Bratland, Eirik; Husebye, Eystein Sverre. 2008. 21-hydroxylase as a T cell autoantigen in autoimmune Addison's disease. Scandinavian Journal of Immunology. 68: 191-191.
  • Husebye, Eystein Sverre. 2008. Endokrinologisk akuttmedisin. Tidsskrift for Den norske legeforening. 128: 574.
  • Kisand, Kai; Link, Maire; Wolff, Anette Susanne Bøe; Meager, A; Meager, Anthony; Tserel, Liina; Org, Tönis; Murumagi, Astrid; Uibo, Raivo; Willcox, Nick; Podkrajsek, Katarina Trebusak; Battelino, Tadej; Lobell, Anna; Kampe, O; Kämpe, Olle; Lima, Kari; Meloni, Antonella; Ergun-Longmire, Berrin; Maclaren, Noel K.; Perheentupa, Jaakko; Krohn, Kai J.E.; Scott, Hamish S.; Husebye, Eystein Sverre; Peterson, Pärt. 2008. Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes. Blood. 112: 2657-2666. doi: 10.1182/blood-2008-03-144634
  • Løvås, Kristian; Husebye, Eystein Sverre. 2008. Replacement therapy for Addison's disease: recent developments. Expert Opinion on Investigational Drugs. 17: 497-509. doi: 10.1517/13543784.17.4.497
  • Magitta, Ng'weina Francis; Pura, Mikulás; Wolff, Anette Susanne Bøe; Vanuga, Peter; Meager, Anthony; Knappskog, Per; Husebye, Eystein Sverre. 2008. Autoimmune polyendocrine syndrome type I in Slovakia: relevance of screening patients with autoimmune Addison's disease. European Journal of Endocrinology. 158: 705-709. doi: 10.1530/EJE-07-0843
  • Magitta, Ng’weina Francis; Bøe, AS; Johansson, S; Skinningsrud, Beate; Lie, Benedicte Alexandra; Myhr, KM; Undlien, Dag Erik; Joner, Geir; Njølstad, Pål R.; Kvien, Tore Kristian; Førre, Øystein Thorleiv; Knappskog, P.M.; Husebye, Eystein. 2008. A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes. Genes and Immunity. doi: 10.1038/gene.2008.85
  • Meloni, Antonella; Furcas, Maria; Cetani, Filomena; Marcocci, Claudio; Falorni, Alberto; Perniola, Roberto; Pura, Mikulás; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Lilic, Desa; Ryan, Kelli R.; Gennery, Andrew R.; Cant, Andrew J.; Abinun, Mario; Spickett, Gavin P.; Arkwright, Peter D.; Denning, David; Costigan, Colm; Dominguez, Maria; McConnell, Vivienne; Willcox, Nick; Meager, Anthony. 2008. Autoantibodies against Type I Interferons as an Additional Diagnostic Criterion for Autoimmune Polyendocrine Syndrome Type I. Journal of Clinical Endocrinology and Metabolism. 93: 4389-4397. doi: 10.1210/jc.2008-0935
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Kämpe, Olle; Perheentupa, Jaakko; Myhre, Anne Grethe; Meager, Anthony; Purushothaman, Radhika; Ten, Svetlana; Husebye, Eystein Sverre. 2008. Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clinical Immunology. 129: 163-169. doi: 10.1016/j.clim.2008.07.002
  • Skinningsrud, Beate; Husebye, Eystein Sverre; Gervin, Kristina; Løvås, Kristian; Lovas, K; Blomhoff, Anne; Wolff, Anette Susanne Bøe; Kemp, E. Helen; Egeland, Thore; Undlien, Dag E. 2008. Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease. European Journal of Human Genetics. 16: 977-982. doi: 10.1038/ejhg.2008.33
  • Skinningsrud, Beate; Husebye, Eystein Sverre; Pearce, Simon H.; McDonald, David O.; Brandal, Kristin; Wolff, Anette Susanne Bøe; Løvås, Kristian; Lovas, K; Egeland, Thore; Egeland, Torstein; Undlien, Dag Erik. 2008. Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. Journal of Clinical Endocrinology and Metabolism. 93: 3310-3317. doi: 10.1210/jc.2008-0821
  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Johansson, Stefan; Bruland, Ove; Løvås, Kristian; Meager, Anthony; Pedersen, Carsten; Husebye, Eystein Sverre; Knappskog, Per. 2008. AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I. Genes and Immunity. 9: 130-136. doi: 10.1038/sj.gene.6364457
  • Bensing, Sophie; Fetissov, Sergueï O.; Mulder, Jan; Perheentupa, Jaakko; Gustafsson, Jan; Husebye, Eystein S.Junior; Oscarson, Mikael; Ekwall, Olov; Crock, Patricia A.; Hökfelt, Tomas; Hulting, Anna-Lena; Kämpe, Olle. 2007. Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1. Proceedings of the National Academy of Science of the United States of America. 104: 949-954. doi: 10.1073/pnas.0610070104
  • Bratland, Eirik; Wolff, Anette Susanne Bøe; Haavik, Jan; Kämpe, Olle; Sköldberg, Filip; Perheentupa, Jaakko; Bredholt, Geir; Knappskog, Per; Husebye, Eystein S.Junior. 2007. Epitope mapping of human aromatic L-amino acid decarboxylase. Biochemical and Biophysical Research Communications - BBRC. 353: 692-698. doi: 10.1016/j.bbrc.2006.12.080
  • Bratland, Eirik; Wolff, Anette Susanne Bøe; Haavik, Jan; Kämpe, Olle; Sköldberg, Filip; Perheentupa, Jaakko; Bredholt, Geir; Knappskog, Per; Husebye, Eystein Sverre. 2007. Epitope mapping of human aromatic L-amino acid decarboxylase. Scandinavian Journal of Immunology. 65: 592-592.
  • Løvås, Kristian; Husebye, Eystein S.Junior. 2007. Continuous subcutaneous hydrocortisone infusion in Addison's disease. European Journal of Endocrinology. 157: 109-112. doi: 10.1530/EJE-07-0052
  • Sanaker, Petter Schandl; Husebye, Eystein S.Junior; Fondenes, Ove; Bindoff, Laurence. 2007. Clinical evolution of Kearns-Sayre syndrome with polyendocrinopathy and respiratory failure. Acta Neurologica Scandinavica. 115: 64-67. doi: 10.1111/j.1600-0404.2007.00850.x
  • Wolff, Anette Susanne Bøe; Erichsen, Martina Moter; Meager, Anthony; Magitta, Ng'weina Francis; Myhre, Anne Grethe; Bollerslev, Jens; Fougner, Kristian J; Lima, Kari; Knappskog, Per; Husebye, Eystein S.Junior. 2007. Autoimmune polyendocrine syndrome type 1 in Norway: Phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene. Journal of Clinical Endocrinology and Metabolism. 92: 595-603. doi: 10.1210/jc.2006-1873
  • Wolff, Anette Susanne Bøe; Myhr, Kjell-Morten; Vedeler, Christian A.; Husebye, Eystein S.Junior. 2007. Fc gamma receptor polymorphisms are not associated with autoimmune Addison's disease. Scandinavian Journal of Immunology. 65: 555-558. doi: 10.1111/j.1365-3083.2007.01932.x
  • Bredholt, Geir; Storstein, Anette Margrethe; Haugen, Monica; Krossnes, Bård Kronen; Husebye, Eystein S.Junior; Knappskog, Per; Vedeler, Christian A. 2006. Detection of autoantibodies to the BTB-kelch protein KLHL7 in cancer sera. Scandinavian Journal of Immunology. 64: 325-335. doi: 10.1111/j.1365-3083.2006.01821.x
  • Husebye, Eystein S.Junior; Bratland, Eirik; Bredholt, Geir; Fridkin, Mati; Dayan, Molly; Mozes, Edna. 2006. The substrate-binding domain of 21-hydroxylase, the main autoantigen in autoimmune Addison's disease, is an immunodominant T cell epitope. Endocrinology. 147: 2411-2416. doi: 10.1210/en.2006-0018
  • Løvås, Kristian; Thorsen, Thor Elias; Husebye, Eystein S.Junior. 2006. Saliva cortisol measurement: simple and reliable assessment of the glucocorticoid replacement therapy in Addison's disease. Journal of Endocrinological Investigation. 29: 727-731.
  • Meager, Anthony; Visvalingam, Kumuthini; Peterson, Pärt; Möll, Kaidi; Murumagi, Astrid; Krohn, Kai; Eskelin, Petra; Perheentupa, Jaakko; Husebye, Eystein S.Junior; Kadota, Yoshihisa; Willcox, Nick. 2006. Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS Medicine. 3: 1152-1164. doi: 10.1371/journal.pmed.0030289
  • Blomhoff, Anne; Kemp, EH; Gawkrodger, DJ; Weetman, AP; Husebye, ES; Akselsen, Hanne Elisabeth; Lie, Benedicte Alexandra; Undlien, Dag Erik. 2005. CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases. Pigment Cell Research. 18.
  • Blomhoff, Anne; Kemp, Helen; Gawkrodger, David J.; Weetman, Anthony P.; Husebye, Eystein S.Junior; Akselsen, Hanne E.; Lie, Benedicte A.; Undlien, Dag E. 2005. CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases. Pigment Cell Research. 18: 55-58.
  • Husebye, Eystein S.Junior; Sthoeger, Zev M.; Dayan, Molly; Zinger, Heidy; Elbirt, Daniel; Levite, Mia; Mozes, Edna. 2005. Autoantibodies to a NR2A peptide of the glutamate/NMDA receptor in sera of patients with systemic lupus erythematosus. Annals of the Rheumatic Diseases. 64: 210-213. doi: 10.1136/ard.2004.029280
  • Løvås, K; Erichsen, Martina M.; Husebye, ES; Fougner, Kristian J.; Svartberg, Johan; Mella, Bjarne; Myhre, Anne Grethe; Berg, Jens Petter; Aarskog, Dagfinn. 2005. Primær binyrebarksvikt - årsaker, diagnostikk og behandling. Tidsskrift for Den norske legeforening. 125: 155-158.
  • Løvås, Kristian; Erichsen, Martina Moter; Husebye, Eystein S.Junior; Fougner, Kristian J; Svartberg, Johan; Mella, B; Myhre, Anne Grethe; Berg, Jens Petter; Aarskog, Dagfinn. 2005. Primær binyrebarksvikt - årsaker, diagnostikk og behandling (=Primary adrenal failure - Causes, diagnostics and therapy). Tidsskrift for Den norske legeforening. 125: 155-158.
  • Løvås, Kristian; Husebye, Eystein S.Junior. 2005. Addison's disease. The Lancet. 365: 2058-2061.
  • Blomhoff, Anne; Lie, Benedicte a.; Myhre, A.G.; Kemp, Helen; Weetman, Anthony P.; Akselsen, Hanne E.; Husebye, Eystein S.Junior; Undlien, Dag E. 2004. Polymorphisms in the cytotoxic T lymphocyte antigen-4 gene region confer susceptibility to Addison's disease. Journal of Clinical Endocrinology and Metabolism. 89: 3474-3476.
  • Bøe, Anette Susanne; Bredholt, G.; Knappskog, Per; Storstein, A.; Vedeler, Christian A.; Husebye, Eystein S.Junior. 2004. Pyridoxal phosphatase is a novel cancer autoantigen in the central nervous system. British Journal of Cancer. 91: 1508-1514.
  • Bøe, Anette Susanne; Bredholt, Geir; Knappskog, Per; Hjelmervik, Trond Ove; Mellgren, Gunnar; Winqvist, Ola; Kämpe, Olle; Husebye, Eystein S.Junior. 2004. Autoantibodies against 21-hydroxylase and side-chain cleavage enzyme in autoimmune Addison's disease are mainly immunoglobulin G1. European Journal of Endocrinology. 150: 49-56.
  • Løvås, Kristian; Husebye, Eystein S.Junior. 2004. Replacement therapy in Addison's disease. Expert Opinion on Pharmacotherapy. 4: 2145-2149.
  • Myhre, Anne Grethe; Stray-Pedersen, A.; Spangen, S.; Eide, E.; Veimo, D.; Knappskog, Per; Abrahamsen, T.G.; Husebye, Eystein S.Junior. 2004. Chronic mucocutaneous candidiasis and primary hypothyroidism in two families. European Journal of Pediatrics. 163: 604-611.
  • Myhre, Anne Grethe; Stray-Pedersen, Asbjørg; Eide, E; Veimo, D.; Knappskog, P.M.; Abrahamsen, Tore G; Husebye, ES. 2004. Chronic mucocutaneous candidiasis and primary hypothyroidism in two families. European Journal of Pediatrics. 163: 604-611.
  • Skoldberg, F.; Rorsman, F.; Perheentupa, J.; Landin-Olsson, M.; Husebye, Eystein S.Junior; Gustafsson, J.; Kämpe, O. 2004. Analysis of antibody reactivity against cysteine sulfinic acid decarboxylase, a pyridoxal phosphate-dependent enzyme, in endocrine autoimmune disease. Journal of Clinical Endocrinology and Metabolism. 89: 1636-1640.
  • Storstein, A.; Monstad, Sissel Evy; Nakkestad, Hanne Linda; Husebye, Eystein S.Junior; Vedeler, Christian A. 2004. Paraneoplastic antibodies against HuD detected by a sensitive radiobinding assay. Journal of Neurology. 251: 197-203.
  • Søderbergh, Annika; Myhre, A.G.; Ekwall, Olov; Gebre-Medhin, Gennet; Hedstrand, Håkan; Landgren, Eva; Miettinen, Aaro; Eskelin, Petra; Halonen, Maria; Tuomi, Tiinamaija; Gustafsson, Jan; Husebye, Eystein S.Junior; Perheentupa, J.; Gylling, Mikhail; Manns, Michael P.; Rorsmann, Fredrik; Kämpe, Olle; Nilsson, Thomas. 2004. Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I. Journal of Clinical Endocrinology and Metabolism. 89: 544-547.
  • Løvås, Kristian; Cooper, J.G.; Thorsen, T.; Thordarson, H.; Husebye, Eystein. 2003. Døgnrytme til besvær. Tidsskrift for Den norske legeforening. 123: 1858-1859.
  • Løvås, Kristian; Husebye, Eystein. 2003. Replacement therapy in Addison's disease. Expert Opinion on Pharmacotherapy. 4: 2145-2149.
  • Løvås, Kristian; Trovik, Thor S; Fougner, Kristian J; Uhlving, Sverre; Nedrebø, Bjørn Gunnar; Myking, Ole Langeland; Husebye, Eystein. 2003. Replacement of Dehydroepiandrosterone in Adrenal Failure: No Benefit for Subjective Healt Status and Sexuality in a 9-Month, Randomized, Parallel Group Clinical Trial. Journal of Clinical Endocrinology and Metabolism. 88: 1112-1118.
  • Myhre, Anne Grethe; Aarsetøy, H.; Undlien, D.E.; Hovdenak, N.; Aksnes, L.; Husebye, Eystein. 2003. High frequency of coeliac disease among patients with autoimmune adrenocortical failure. Scandinavian Journal of Gastroenterology. 38: 511-515.
  • Sköldberg, Filip; Portela-Gomes, Guida M.; Grimelius, Lars; Nilsson, Gunnar; Perheentupa, Jaakko; Betterle, Corrado; Husebye, Eystein; Gustafsson, Jan; Rönnblom, Anders; Rorsman, Fredrik; kÄMPE, oLLE. 2003. Histidine decarboxylase, a pyridoxal phosphate-dependent enzyme, is an autoantigen of gastric enterochromaffin-like cells. Journal of Clinical Endocrinology and Metabolism. 88: 1445-1452.
  • Bøe, Anette Susanne; Knappskog, Per Morten; Myhre, Anne Grete; Sørheim, Jan I; Husebye, Eystein. 2002. Mutational analysis of the autoimmune regulator gene in sporadic autoimmune Addison`s disease can reveal patients with unidentified autoimmune polyendocrine syndrome type I. European Journal of Endocrinology. 146: 519-522.
  • Halonen, Maria; Bjørses, Petra; Myhre, Anne Grethe; Perheentupa, Jaako; Husebye, Eystein; kÄMPE, oLLE; Rorsman, Fredrik; Peltonen, Leena; Ulmanen, Ismo; Partanen, J. 2002. Autoimmune Regulator and Human Leucocyte Antigen Genotypes as Determinants of the Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Phenotype. Journal of Clinical Endocrinology and Metabolism. 87: 2568-2574.
  • Husebye, Eystein. 2002. Hypotyreose. Tidsskrift for Den norske legeforening. 122: 983-983.
  • Løvås, Kristian; Husebye, Eystein. 2002. High prevalence and increasing incidence of Addison's disease in western Norway. Clinical Endocrinology. 56: 787-791.
  • Løvås, Kristian; Loge, Jon Håvard; Husebye, Eystein. 2002. Subjective health status in Norwegian patients with Addison's disease. Clinical Endocrinology. 56: 581-588.
  • Myhre, Anne Grethe; Undlien, Dag Erik; Løvås, Kristian; Uhlving, Sverre; Nedrebø, Bjørn; Fougner, Kristian; Trovik, Thor; Sørheim, Jan Inge; Husebye, Eystein. 2002. Autoimmune adrenocortical failure in Norway. Autoantibodies and HLA class II associations related to clinical features. Journal of Clinical Endocrinology and Metabolism. 87: 618-623.
  • Nedrebø, Bjørn G; Holm, Pål Ivar; Uhlving, Sverre; Sørheim, Jan I; Skeie, Svein; Eide, Geir Egil; Husebye, Eystein; Lien, Ernst Asbjørn; Aanderud, Sylvi J. 2002. Predictors of outcome and comparison of different drug regimens for the prevention of relapse in patients with Graves' disease. European Journal of Endocrinology. 147: 583-589.
  • Nesje, Lars Birger; Varhaug, Jan Erik; Husebye, Eystein; Ødegaard, Svein. 2002. Endoscopic ultrasonography for preoperative diagnosis and localization of insulinomas. Scandinavian Journal of Gastroenterology. 37: 732-737.
  • Astuti, D.; Latif, F.; Dallol, A.; Dahia, P. L.; Douglas, F.; George, E.; Skoldberg, F.; Husebye, Eystein; Eng, C.; Maher, E. R. 2001. Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. American Journal of Human Genetics. 69: 49-54.
  • Hedstrand, Håkan; Ekwall, Olov; Olsson, Mats J.; Landgren, Eva; Kemp, E. Helen; Weetman, Anthony P.; Perheentupa, Jaakko; Husebye, Eystein; Gustafsson, Jan; Betterle, Corrado; Kämpe, Olle; Rorsman, Fredrik. 2001. The transcription factors SOX9 and SOX10 are vitiligo autoantigens in autoimmune polyendocrine syndrome type I. Journal of Biological Chemistry. 276: 35390-35395.
  • Husebye, Eystein. 2001. Acute adrenal insufficiency--symptoms and treatment. Tidsskrift for Den norske legeforening. 121: 1260.
  • Myhre, Anne Grethe; Halonen, M.; Eskelin, P.; Ekwall, Olov; Hedstrand, Håkan; Rorsman, Fredrik; Kämpe, Olle; Husebye, Eystein. 2001. Autoimmune polyendocrine syndrome type 1 (APS I) in Norway. Clinical Endocrinology. 54: 211-217.
  • Ekwall, O; Hedstrand, HH; Haavik, Jan; Perheentupa, J; Betterle, C; Gustafsson, J; Husebye, Eystein S.Junior; Kämpe, O; Rorsman, F. 2000. Pteridin dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 85: 2944-2950.
  • Ekwall, Olov; Hedstrand, Håkan; Haavik, Jan; Perheentupa, Jaakko; Betterle, Corrado; Gustafsson, Jan; Husebye, Eystein; Rorsman, Fredrik; Këmpe, Olle. 2000. Pteridine-dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 85: 2944-2950.
  • Gebre-Medhin, S; Husebye, Eystein; Mallmin, H; Helström, L; Berne, C; Karlsson, FA; Kämpe, O. 2000. Oral dehydroepiandrosterone (DHEA) replacement therapy in women with Addison's disease. Clinical Endocrinology. 52: 775-780.
  • Gebre-Medhin, [Mangler fornavn]; Husebye, Eystein S.Junior; Mallmin, H; Helström, L; Berne, C; Karlsson, FA; Kämpe, O. 2000. Oral dehydroepiandrosterone (DHEA) replacement therapy in women with Addison's disease. Clinical Endocrinology. 52: 775-780.
  • Hedstrand, HH; Ekwall, O; Haavik, Jan; Landgren, E; Betterle, J; Perheentupa, J; Gustafsson, J; Husebye, Eystein S.Junior; Rorsman, F; Kämpe, O. 2000. Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I. Biochemical and Biophysical Research Communications - BBRC. 267: 456-461.
  • Hedstrand, Håkan; Ekwall, Olov; Haavik, Jan; Landgren, E.; Betterle, Corrado; Perheentupa, Jaakko; Gustafsson, Jan; Husebye, Eystein; Rorsman, Fredrik; Këmpe, Olle. 2000. Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I. Biochemical and Biophysical Research Communications - BBRC. 267: 456-461.
  • Husebye, Eystein S.Junior; Bøe, Anette Susanne; Rorsman, F; Kämpe, O; Aakvaag, A; Rygh, T; Flatmark, Torgeir; Haavik, Jan. 2000. Inhibition of aromatic 1-amino acid decarboxylase by human autoantibodies. Clinical and Experimental Immunology. 120: 420-423.
  • Husebye, Eystein; Bøe, Anette Susanne; Rorsman, Fredrik; Këmpe, Olle; Aakvaag, T.; Rygh, T.; Flatmark, Torgeir; Haavik, Jan. 2000. Inhibition of aromatic L-amino acid decarboxylase activity by human autoantibodies. Clinical and Experimental Immunology. 120: 420-423.
  • Søderbergh, A; Rorsman, F; Halonen, M; Ekwall, O; Björses, P; Kämpe, O; Husebye, Eystein. 2000. Autoantibodies against aromatic L-amino acid decarboxylase delineate a subgroup of patients with Addison's disease. Journal of Clinical Endocrinology and Metabolism. 85: 460-463.
  • Søderbergh, A; Rorsman, F; Halonen, M; Ekwall, O; Björses, P; Kämpe, O; Husebye, Eystein S.Junior. 2000. Autoantibodies against aromatic L-amino acid decarboxylase delineate a subgroup of patients with Addison's disease. Journal of Clinical Endocrinology and Metabolism. 85: 460-463.
  • Hedstrand, H.H.; Perheentupa, J; Ekwall, O; Gustafsson, J; Michaelsson, G; Husebye, Eystein S.Junior; Rorsman, F; Kampe, O. 1999. Antibodies Against Hair Follicles are Associated with Alopecia Totalis in Autoimmune Polyendocrine Syndrome Type I. Journal of Investigative Dermatology. 113: 1054-1058.
  • Ekwall, O; Hedstrand, H.H.; Grimelius, L; Haavik, Jan; Perheentupa, J; Gustafsson, J; Husebye, Eystein S.Junior; Kampe, O; Rorsman, F. 1998. Identification of tryptophan hydroxylase as an intestinal autoantigen. The Lancet. 352: 279-283.
  • Ekwall, O; Hedstrand, H.H.; Grimelius, L; Haavik, Jan; Perheentupa, J; Gustafsson, J; Husebye, Eystein S.Junior; Kämpe, O; Rorsman, F. 1998. Identification of tryptophan hydroxylase as an intestinal autoantigen. The Lancet. 352: 279-283.
  • Husebye, Eystein S.Junior; Aanderud, Sylvi. 1998. Primær binyrebarksvikt - en diagnostisk utfordring. Tidsskrift for Den norske legeforening. 118: 542-544.
  • Kemp, E; Ajjan, R.A; Husebye, Eystein S.Junior; Peterson, P; Uibo, R; Imrie, H; Pearce, S; Watson, P.F; Weetman, A.P. 1998. A cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism is associated with autoimmune Addison's disease in English patients. Clinical Endocrinology. 49: 609-614.
  • Myhre, A-G; Bjørses, P; Dalen, A; Husebye, Eystein S.Junior. 1998. Three sisters with Addison's disease. Journal of Clinical Endocrinology and Metabolism. 83: 4204-4206.
  • Skjöldberg, F; Grimelius, L; Rorsman, F; Van Schothorst, E.W; Winqvist, O; Karlsson, F.A; Åkerström, G; Kämpe, O; Husebye, Eystein S.Junior. 1998. A family with hereditary extra-adrenal paragangliomas without evidence for mutations in the Von Hippel Lindau disease or ret genes. Clinical Endocrinology. 48: 11-16.
  • Gebre-Medhin, G; Husebye, Eystein S.Junior; Rorsman, F; Gustafsson, J; Winqvist, O; Kämpe, O. 1997. Cytochrome P450IA2 and aromatic L-amino acid decarboxylase are hepatic autoantigens in autoimmune polyendocrine syndrome type I. FEBS Letters. 412: 439-445.
  • Husebye, Eystein S.Junior; Gebre-Medhin, G; Tuomi, T; Perheentupa, J; Landin-Olsson, M; Gustafsson, J; Rorsman, F; Kämpe, O. 1997. Autoantibodies against aromatic L-amino acid decarboxylase in autoimmune polyendocrine syndrome type I correlate with the presence of autoimmune hepatitis and vitiligo. Journal of Clinical Endocrinology and Metabolism. 82: 147-150.
  • Stridsberg, M; Husebye, Eystein S.Junior. 1997. Chromogranin A and chromogranin B in phaeochromocytoma. European Journal of Endocrinology. 136: 67-73.
Reports and theses
  • Husebye, Eystein. 2000. Feokromocytom i Neuroindokrine tumorer, en veiledning til diagnostikk og behandling. MANGLER. 2 pages.
  • Husebye, Eystein S.Junior. 2000. Feokromocytom i Neuroindokrine tumorer, en veiledning til diagnostikk og behandling. Ukjent, Ukjent. 2 pages.
  • Husebye, Eystein S.Junior. 1990. Stimulus-secretion coupling in chromaffin cells of the bovine adrenal medulla : with special reference to the role of phospholipid metabolism. University of Bergen, Department of Biochemistry, Bergen. 1 pages.
Book sections
  • Husebye, Eystein. 2003. Cushings syndrom. 49-56. In:
    • Johansen, Liv; Moene, Astrid; Huseth, Gerd Kari; Berg, Arnfinn. 2003. Livsboka. 151 pages. ISBN: 82-303-0058-5.

More information in national current research information system (CRIStin)

Consultant in endocrinology and internal medicine

Current projects

Co-ordinator of the EU FP7 project Euradrenal