Karl Albert Brokstad's picture
Karl Albert
Brokstad
Senior Engineer
Visit Address: 
Haukeland universitetssykehus, Laboratoriebygget
5021 Bergen
Postal Address: 
Postboks 7804
5021 Bergen
Phone: 
+47 55 97 46 22
+47 988 43 314
Download vCard
Books
  • Brokstad, Karl Albert. 2003. Methods in Molecular Medicine focusing on Methods in Viral Immunity.
Journal articles
  • Aqrawi, Lara Adnan; Kvarnström, Marika; Brokstad, Karl Albert; Jonsson, Roland; Skarstein, Kathrine; Wahren-Herlenius, Marie. 2014. Ductal epithelial expression of Ro52 correlates with inflammation in salivary glands of patients with primary Sjögren's syndrome. Clinical and Experimental Immunology. 177: 244-252. doi: 10.1111/cei.12341
  • Pedersen, Gabriel; Höschler, Katja; Solbak, Sara Marie Øie; Bredholt, Geir; Pathirana, Rishi; Afsar, Aram; Breakwell, Lucy; Nøstbakken, Jane Kristin; Raae, Arnt Johan; Brokstad, Karl Albert; Sjursen, Haakon; Zambon, Maria; Cox, Rebecca Jane. 2014. Serum IgG titres, but not avidity, correlates with neutralizing antibody response after H5N1 vaccination. Vaccine. 32: 4550-4557. doi: 10.1016/j.vaccine.2014.06.009
  • Aqrawi, Lara Adnan; Brokstad, Karl Albert; Skarstein, Kathrine. 2013. Autoantigen-specific memory cell pattern in patients with Primary Sjögren's syndrome. Scandinavian Journal of Immunology. 77: 296-296.
  • Aqrawi, Lara Adnan; Skarstein, Kathrine; Øijordsbakken, Gunnvor; Brokstad, Karl Albert. 2013. Ro52- and Ro60-specific B cell pattern in the salivary glands of patients with primary Sjögren's syndrome. Clinical and Experimental Immunology. 172: 228-237. doi: 10.1111/cei.12058
  • Jonsson, Roland; Theander, E; Sjostrom, B; Brokstad, Karl Albert; Henriksson, G. 2013. Autoantibodies Present Before Symptom Onset in Primary Sjogren Syndrome. Journal of the American Medical Association (JAMA). 310: 1854-1855.
  • Jonsson, Roland; Theander, Elke; Sjöström, Bitte; Brokstad, Karl Albert; Henriksson, Gunnel. 2013. Autoantibodies Present Before Symptom Onset in Primary Sjögren Syndorme. Journal of the American Medical Association (JAMA). 310: 1854-1855. doi: 10.1001/jama.2013.278448
  • Qu, Yi; Øyan, Anne Margrete; Liu, Run-hui; Hua, Yaping; Zhang, Jiagang; Hovland, Randi; Popa, Mihaela Lucia; Liu, Xiaojun; Brokstad, Karl Albert; Simon, Ronald; Molven, Anders; Lin, Biaoyang; Zhang, Weidong; McCormack, Emmet; Kalland, Karl-Henning; Ke, Xisong. 2013. Generation of prostate tumor-initiating cells is associated with elevation of reactive oxygen species and IL-6/STAT3 signaling. Cancer Research. 73: 7090-7100. doi: 10.1158/0008-5472.CAN-13-1560
  • Aqrawi, Lara Adnan; Brokstad, Karl Albert; Jakobsen, Kjerstin; Jonsson, Roland; Skarstein, Kathrine. 2012. Low number of memory B cells in the salivary glands of patients with primary Sjögren's syndrome. Autoimmunity. 45: 547-555. doi: 10.3109/08916934.2012.712170
  • Aqrawi, Lara Adnan; Skarstein, Kathrine; Bredholt, Geir; Brun, Johan G; Brokstad, Karl Albert. 2012. Autoantigen-specific memory B cells in primary Sjögren's syndrome. Scandinavian Journal of Immunology. 75: 61-68. doi: 10.1111/j.1365-3083.2011.02625.x
  • Aqrawi, Lara Adnan; Skarstein, Kathrine; Oijordsbakken, G; Brokstad, Karl Albert. 2012. Ro52-and Ro60-specific B cell pattern in the salivary glands of patients with primary Sjogren's syndrome. Immunology. 137: 339-339.
  • Björkman, Lars; Brokstad, Karl Albert; Moen, Ketil; Jonsson, Roland. 2012. Minor changes in serum levels of cytokines after removal of amalgam restorations. Toxicology Letters. 211: 120-125. doi: 10.1016/j.toxlet.2012.03.769
  • Brauner, Susanna; Kvarnstöm, Marika; Görgen, Sabrina; Franzén-Malmros, Michaela; Brokstad, Karl Albert; Folkersen, Lasse; Klareskog, Christina Trollmo Lars; Jonsson, Roland; Nordmark, Gunnel; Malmström, Vivi; Wahren-Herlenius, Marie Louise Max. 2012. Hyperreactive B cells upon endosomal TLR triggering underlying primary Sjögren's Syndrome. Scandinavian Journal of Immunology. 76: 199-200. doi: 10.1111/j.1365-3083.2012.02735.x
  • Jul-Larsen, Åsne; Madhun, Abdullah Sami; Brokstad, Karl Albert; Montomoli, Emanuele; Yusibov, Vidadi; Cox, Rebecca Jane. 2012. The human potential of a recombinant pandemic influenza vaccine produced in tobacco plants. Human Vaccines & Immunotherapeutics. 8: 653-661. doi: 10.4161/hv.19503
  • Brauner, Susanna; Kvarnstöm, Marika; Görgen, Sabrina; Franzén-Malmros, Michaela; Brokstad, Karl Albert; Folkersen, Lasse; Trollmo, Christina; Klareskog, Lars; Jonsson, Roland; Malmström, Vivi; Wahren-Herlenius, Marie. 2011. Vaccination of patients with primary Sjögren's syndrome reveals hyperreactive B cell compartment with a skewed maturation pattern. Annals of the Rheumatic Diseases. 70: A67-A67. doi: 10.1136/ard.2010.149005.23
  • Brauner, Susanna; Kvarnstöm, Marika; Görgen, Sabrina; Franzén-Malmros, Michaela; Brokstad, Karl Albert; Trollmo, Christina; Klareskog, Lars; Jonsson, Roland; Malmström, Vivi; Wahren-Herlenius, Marie. 2011. Vaccination of Patients with Primary Sjogren's Syndrome Reveals Hyperreactive B Cell Compartment. Scandinavian Journal of Immunology. 73: 369-369.
  • Reksten, Tove Ragna; Brokstad, Karl Albert; Jonsson, Roland; Brun, Johan G; Jonsson, Malin V. 2011. Implications of long-term medication of oral steroids and antimalarial drugs in primary Sjögren's syndrome. International Immunopharmacology. 11: 2125-2129. doi: 10.1016/j.intimp.2011.09.006
  • Szyszko, Ewa Alicja; Brokstad, Karl Albert; Øijordsbakken, Gunnvor; Jonsson, Malin V; Jonsson, Roland; Skarstein, Kathrine. 2011. Salivary glands of primary Sjögren's syndrome patients express factors vital for plasma cell survival. Arthritis Research & Therapy. 13. 18 pages. doi: 10.1186/ar3220
  • Szyszko, Ewa Alicja; Brun, Johan G; Skarstein, Kathrine; Peck, Ammon B.; Jonsson, Roland; Brokstad, Karl Albert. 2011. Phenotypic diversity of peripheral blood plasma cells in primary Sjögren’s Syndrome. Scandinavian Journal of Immunology. 73: 18-28. doi: 10.1111/j.1365-3083.2010.02475.x
  • Szyszko, Ewa Alicja; Skarstein, Kathrine; Jonsson, Roland; Brokstad, Karl Albert. 2011. Distinct phenotypes of plasma cells in spleen and bone marrow of autoimmune NOD.B10.H2b mice. Autoimmunity. 44: 415-426. doi: 10.3109/08916934.2010.545847
  • Theander, Elke; Vasaitis, Lillian; Bäcklund, Eva; Nordmark, Gunnel; Warfvinge, Gunnar; Liedholm, Rolf; Brokstad, Karl Albert; Jonsson, Roland; Jonsson, Malin V. 2011. Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjögren's syndrome. Annals of the Rheumatic Diseases. 70: 1363-1368. doi: 10.1136/ard.2010.144782
  • Huszthy, Peter Csaba; Brokstad, Karl Albert; Bjerkvig, Rolf; Miletic, Hrvoje. 2010. Successful engraftment of glioblastoma biopsy spheroids in immunocompetent rats. European Journal of Cancer. 8: 76-76.
  • Reksten, Tove Ragna; Jonsson, Malin V; Brokstad, Karl Albert. 2010. The Value of Using Diseased Controls in Studies of Autoimmune Rheumatic Diseases. Scandinavian Journal of Immunology. 71: 491-492.
  • Reksten, Tove Ragna; Jonsson, Roland; Brokstad, Karl Albert; Jonsson, Malin V. 2010. Prednisolon Reduce Cytokine but Increase Autoantibody Levels in Patients with Primary Sjogren's Syndrome. Scandinavian Journal of Immunology. 71: 491-491.
  • Cox, Rebecca Jane; Major, Diane; Hauge, Solveig; Madhun, Abdullah Sami; Brokstad, Karl Albert; Kuhne, Mirjam; Smith, Jon; Vogel, Frederick R.; Zambon, Maria; Haaheim, Lars Reinhardt; Wood, John. 2009. A cell-based H7N1 split influenza virion vaccine confers protection in mouse and ferret challenge models. Influenza and Other Respiratory Viruses. 3: 107-117. doi: 10.1111/j.1750-2659.2009.00082.x
  • Ellertsen, Linda Kathrine; Storla, Dag G; Diep, Lien M; Brokstad, Karl A; Wiker, Harald G; Hetland, Geir. 2009. Allergic sensitisation in tuberculosis patients at the time of diagnosis and following chemotherapy. BMC Infectious Diseases. 9. 9 pages. doi: 10.1186/1471-2334-9-100
  • Hauge, Solveig; Madhun, Abdullah Sami; Brokstad, Karl Albert; Haaheim, Lars Reinhardt; Cox, Rebecca Jane; Zambon, M; Wood, J; Haaheim, LR; Cox, RJ. 2009. The Immunogenicity of a Cell-derived H7N1 Split Influenza Virion Vaccine in Mice. Scandinavian Journal of Immunology. 69: 576-578. doi: 10.1111/j.1365-3083.2009.02254.x
  • Hovden, Arnt-Ove; Brokstad, Karl Albert; Major, Diane; Wood, John; Haaheim, Lars Reinhardt; Cox, Rebecca Jane. 2009. A pilot study of the immune response to whole inactivated avian influenza H7N1 virus vaccine in mice. Influenza and Other Respiratory Viruses. 3: 21-28. doi: 10.1111/j.1750-2659.2009.00075.x
  • Olsnes, Carla; Stavang, Helen Åse Margrethe; Brokstad, Karl Albert; Olofsson, Jan; Aarstad, Hans Jørgen. 2009. Chemokines are secreted by monocytes following OK-432 (lyophilized Streptococcus pyogenes) stimulation. BMC Immunology. 10. Published 2009-01-28. doi: 10.1186/1471-2172-10-6
  • Reksten, Tove Ragna; Jonsson, Malin V; Szyszko, Ewa Alicja; Brun, Johan G; Jonsson, Roland; Brokstad, Karl Albert. 2009. Cytokine and autoantibody profiling related to histopathological features in primary Sjögren's syndrome. Rhematology Int. 48: 1102-1106. doi: 10.1093/rheumatology/kep149
  • Jonsson, Malin V; Brokstad, Karl Albert; Skarstein, Kathrine; Berggreen, Ellen. 2008. Salivary gland interstitial fluid cytokines in NOD mice. Arthritis and Rheumatism. 58: S796-S796.
  • Szyszko, Ewa Alicja; Skarstein, Kathrine; Jonsson, Roland; Brokstad, Karl Albert. 2008. Heterogeneity of plasma cell subsets found in the bone marrow of autoimmune NOD.B10.H2b mice. Scandinavian Journal of Immunology. 68: 206-206.
  • Hauge, Solveig; Madhun, Abdullah Sami; Cox, Rebecca Jane; Brokstad, Karl Albert; Haaheim, Lars Reinhardt. 2007. A comparison of the humoral and cellular immune responses at different immunological sites after split influenza virus vaccination of mice. Scandinavian Journal of Immunology. 65: 14-21. doi: 10.1111/j.1365-3083.2006.01862.x
  • Jonsson, Roland; Bolstad, Anne Isine; Brokstad, Karl Albert; Brun, Johan G. 2007. Sjögren's syndrome - A plethora of clinical and immunological phenotypes with a complex genetic background. Annals of the New York Academy of Sciences. 1108: 433-447. doi: 10.1196/annals.1422.046
  • Jonsson, Roland; Nginamau, Elisabeth Sivy; Szyszko, Ewa Alicja; Brokstad, Karl Albert. 2007. Role of B cells in Sjögren's syndrome - from benign lymphoproliferation to overt malignancy. Frontiers in Bioscience. 12: 2159-2170. doi: 10.2741/2219
  • Cox, Rebecca Jane; Brokstad, Karl Albert; Haaheim, Lars Reinhardt. 2006. Pandernic influenza vaccine development: time is of the essence. Expert Review of Vaccines. 5: 603-606.
  • Cox, Rebecca Jane; Brokstad, Karl Albert; Haaheim, Lars Reinhardt. 2006. Pandemic influenza vaccine development: time is of the essence. Expert Review of Vaccines. doi: 10.1586/14760584.5.5.603
  • Cox, Rebecca Jane; Haaheim, Lars Reinhardt; Eriksson, Jens Christian; Madhun, Abdullah Sami; Brokstad, Karl Albert. 2006. The humoral and cellular responses induced locally and systematically after parenteral influenza vaccination in man. Vaccine. 24: 6577-6580.
  • Cox, Rebecca Jane; Hovden, Arnt-Ove; Brokstad, Karl Albert; Szyszko, Ewa Alicja; Madhun, Abdullah Sami; Haaheim, Lars Reinhardt. 2006. The humoral immune response and protective efficacy of vaccination with inactivated split and whole influenza virus vaccines in BALB/c mice. Vaccine. 24: 6585-6587. doi: 10.1016/j.vaccine.2006.05.040
  • Danielsen, Arild; Tynning, Turid Liv; Brokstad, Karl Albert; Olofsson, Jan; Davidsson, Åke. 2006. Interleukin 5, IL6, IL12, IFN-gamma, RANTES and Fractalkine in human nasal polyps, turbinate mucosa and serum. European Archives of Oto-Rhino-Laryngology. 263: 282-289. doi: 10.1007/s00405-005-1031-1
  • Jonsson, Malin V; Delaleu, Nicolas; Brokstad, Karl Albert; Berggreen, Ellen; Skarstein, Kathrine. 2006. Impaired salivary gland function in NOD mice - Association with changes in cytokine profile but not with histopathologic changes in the salivary gland. Arthritis and Rheumatism. 54: 2300-2305. doi: 10.1002/art.21945
  • Jonsson, Malin V; Delaleu, Nicolas; Brokstad, Karl Albert; Berggreen, Ellen; Skarstein, Kathrine. 2006. Impaired salivary gland function in nod mice - Association with changes in cytokine profile but not with salivary gland histopathology. Arthritis and Rheumatism. 54: S707-S707.
  • Mittelholzer, Camilla; Brokstad, Karl Albert; Pauksens, Karlis; Jonsson, Roland; Brytting, Maria; Linde, Annika. 2006. Human cell lines used in a micro neutralization test for measuring influenza-neutralizing antibodies. Scandinavian Journal of Immunology. 63: 257-264. doi: 10.1111/j.1365-3083.2006.01740.x
  • Szyszko, Ewa Alicja; Brokstad, Karl Albert; Cox, Rebecca Jane; Hovden, Arnt-Ove; Madhun, Abdullah Sami; Haaheim, Lars Reinhardt. 2006. Impact of influenza vaccine formulation with a detailed analysis of the cytokine response. Scandinavian Journal of Immunology. 64: 467-475. doi: 10.1111/j.1365-3083.2006.01805.x
  • Davidsson, Åke; Eriksson, Jens Christian; Rudblad, S; Brokstad, Karl Albert. 2005. Influenza specific serum IgE is present in non-allergic subjects. Scandinavian Journal of Immunology. 62: 560-561.
  • Garberg, Hilde Kristin; Jonsson, Roland; Brokstad, Karl Albert. 2005. The serological pattern of autoantibodies to the Ro52, Ro60, and La48 autoantigens in primary Sjögren's syndrome patients and healthy controls. Scandinavian Journal of Rheumatology. 34: 49-55. doi: 10.1080/03009740510017940
  • Omdal, Roald; Brokstad, Karl; Waterloo, Knut K; Koldingsnes, Wenche; Jonsson, Ronald; Jonsson, Roland; Mellgren, Svein Ivar. 2005. Neuropsychiatric disturbances in SLE are associated with antibodies against NMDA receptors. European Journal of Neurology. 12: 392-398.
  • Cox, Rebecca Jane; Brokstad, Karl; Ogra, Pearay. 2004. Influenza virus: Immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines. Scandinavian Journal of Immunology. 59: 1-15.
  • Eriksson, Jens Christian; Davidsson, A; Garberg, Hilde Kristin; Brokstad, Karl. 2004. Lymphocyte distribution in the tonsils prior to and after influenza vaccination. Vaccine. 22: 57-63.
Reports and theses
  • Brokstad, Karl Albert. 1995. Qualitative, quantitative and kinetic aspects of the humoral immune response induced systemically and locally after influenza vaccination.
Book sections
  • Jonsson, Roland; Brokstad, Karl Albert. 2007. Immunologi og andre fagfelt. Kapittel 15, pages 141-147. In:
    • Isaksen, Runo Andre; Jonsson, Roland. 2007. Immunologisk forskning i Bergen, Broegelmanns Forskningslaboratorim 1957-2007. 184 pages. ISBN: 978-82-7128-434-3.
  • Madhun, Abdullah Sami; Cox, Rebecca Jane; Haaheim, Lars Reinhardt; Jonsson, Roland; Brokstad, Karl Albert. 2004. The kinetics of the systemic and local immune response to parenteral influenza vaccination. International Series 1263, pages 515-518. In:
    • Kawaoka, Yoshihiro. 2004. Options for the Control of Influenza V. 850 pages.

More information in national current research information system (CRIStin)

Research groups