Tilbake til normal visning Norstruct projects Internal NORSTRUCT projects are to a large extent dealing with molecular studies of fish pathogenic organism and fish defence systems. The psychrophilic fish pathogen, Vibrio salmonicida, is used as model organism in the study of systems involved in virulence, oxidative stress, etc. The structure-function relation studies of these systems are supported by proteomics and functional studies. The “systems” studies are strongly coupled with studies of more basic problems, i.e. molecular basis for cold-activity, protein recognition and DNA repair enzymes. Currently active internal NORSTRUCT projects: Project no Project title Project leader NORSTR-015 Structural genomics studies of Vibrio salmonicida Nils Peder Willassen NORSTR-017 Structural studies of Atlantic salmon interferons Børre Robertsen NORSTR-018 Structural studies of p38 MAP kinase and its kinase kinase activator MKK6 in Atlantic salmon Jorun B. Jørgensen NORSTR-019 Structural studies of molecules involved in the bacterial defense in Atlantic salmon Trond Ø. Jørgensen NORSTR-020 Structural studies of cod bactericidal permeability-increasing protein/lipopolysaccaride-binding pro Trond Ø. Jørgensen NORSTR-022 Cold adaptation and molecular design of cod Uracil DNA glycosylase A.O.Smalås and N.P.Willassen NORSTR-027 Determination of molecular descriptors from analysis of sequence and genome data B.O.Brandsdal and A.O.Smalås NORSTR-053 Crystallographic studies of lactate oxidase from Aerococcus viridans Edward Hough NORSTR-054 Crystallographic studies of the Antarctic alkaline phosphatase TAB5 Edward Hough NORSTR-055 Modelling of reactions in cold-active enzymes B.O.Brandsdal and A.O.Smalås NORSTR-058 Protein-DNA interactions at atomic levels E. Moe and A.O.Smalås NORSTR-064 Structural basis for the primary specificity of serine proteinases A.O.Smalås and N.P.Willassen The Norwegian Structural Biology Centre University of Tromsø, 9037 Tromsø, tlf. 77 64 40 70 Contact: professor Arne O. Smalås