Norstruct projects
Internal NORSTRUCT projects are to a large extent dealing with molecular studies of fish pathogenic organism and fish defence systems. The psychrophilic fish pathogen, Vibrio salmonicida, is used as model organism in the study of systems involved in virulence, oxidative stress, etc. The structure-function relation studies of these systems are supported by proteomics and functional studies. The “systems” studies are strongly coupled with studies of more basic problems, i.e. molecular basis for cold-activity, protein recognition and DNA repair enzymes.
Currently active internal NORSTRUCT projects:
| Project no |
Project title |
Project leader |
| NORSTR-015 |
Structural genomics studies of Vibrio salmonicida |
Nils Peder Willassen |
| NORSTR-017 |
Structural studies of Atlantic salmon interferons |
Børre Robertsen |
| NORSTR-018 |
Structural studies of p38 MAP kinase and its kinase kinase activator MKK6 in Atlantic salmon |
Jorun B. Jørgensen |
| NORSTR-019 |
Structural studies of molecules involved in the bacterial defense in Atlantic salmon |
Trond Ø. Jørgensen |
| NORSTR-020 |
Structural studies of cod bactericidal permeability-increasing protein/lipopolysaccaride-binding pro |
Trond Ø. Jørgensen |
| NORSTR-022 |
Cold adaptation and molecular design of cod Uracil DNA glycosylase |
A.O.Smalås and N.P.Willassen |
| NORSTR-027 |
Determination of molecular descriptors from analysis of sequence and genome data |
B.O.Brandsdal and A.O.Smalås |
| NORSTR-053 |
Crystallographic studies of lactate oxidase from Aerococcus viridans |
Edward Hough |
| NORSTR-054 |
Crystallographic studies of the Antarctic alkaline phosphatase TAB5 |
Edward Hough |
| NORSTR-055 |
Modelling of reactions in cold-active enzymes |
B.O.Brandsdal and A.O.Smalås |
| NORSTR-058 |
Protein-DNA interactions at atomic levels |
E. Moe and A.O.Smalås |
| NORSTR-064 |
Structural basis for the primary specificity of serine proteinases |
A.O.Smalås and N.P.Willassen |
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