Harleen Grewal's picture
Harleen
Grewal
Professor
, Senior consultant (Haukeland hospital)
Visit Address: 
Haukeland universitetssykehus, Laboratoriebygget
5021 Bergen
Postal Address: 
Postboks 7804
5021 Bergen
Phone: 
+47 55 97 46 31
+47 994 50 554
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Books
  • Grewal, Harleen; Friis, Henrik. 2006. The Role of Nutrition in Tuberculosis. In: Practical Approach to Tuberculosis Management. 7 pages. ISBN: 81-8061-767-X.
Journal articles
  • Jenum, Synne; Grewal, Harleen; Hokey, David A.; Kenneth, John; Vaz, Mario; Doherty, Timothy Mark; Jahnsen, Frode Lars. 2014. The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy Indian adolescents. PLoS ONE. 9. doi: 10.1371/journal.pone.0101224
  • Jenum, Synne; Selvam, Sumithra; Mahelai, Diana; Jesuraj, Nelson; Cardenas, Vicky; Kenneth, John; Hesseling, Anneke C.; Doherty, T Mark; Vaz, Mario; Grewal, Harleen. 2014. Influence of Age and Nutritional Status on the Performance of the Tuberculin Skin Test and QuantiFERON®-TB Gold In-Tube in Young Children Evaluated for Tuberculosis in Southern India. The Pediatric Infectious Disease Journal.
  • Mukherjee, Aparna; Saini, Savita; Kabra, Sushil Kumar; Gupta, Nidhi; Singh, Varinder; Singh, Saraman; Bhatnagar, Shinjini; Saini, Deepti; Grewal, Harleen; Lodha, Rakesh. 2014. Effect of micronutrient deficiency on QuantiFERON-TB Gold In-Tube test and tuberculin skin test in diagnosis of childhood intrathoracic tuberculosis. European Journal of Clinical Nutrition. 68: 38-42. doi: 10.1038/ejcn.2013.216
  • Sivakumaran, Dhanasekaran; Jenum, Synne; Stavrum, Ruth; Ritz, Christian; Kenneth, John; Vaz, Mario; Doherty, Timothy Mark; Grewal, Harleen. 2014. Concordant or discordant results by the tuberculin skin test and the quantiFERON-TB test in children reflect immune biomarker profiles. Genes and Immunity. 15: 265-274. doi: 10.1038/gene.2014.13
  • Stavrum, Ruth; PrayGod, George; Range, Nyagosya; Faurholt-Jepsen, Daniel; Jeremiah, Kidola; Faurholt-Jepsen, Maria; Krarup, Henrik; Aabye, Martine G.; Changalucha, John; Friis, Henrik; Andersen, Aase B.; Grewal, Harleen. 2014. Increased level of acute phase reactants in patients infected with modern mycobacterium tuberculosis genotypes in mwanza, tanzania. BMC Infectious Diseases. 14. doi: 10.1186/1471-2334-14-309
  • Faurholt-Jepsen, Daniel; Range, Nyagosya; PrayGod, George; Jeremiah, Kidola; Faurholt-Jepsen, Maria; Aabye, Martine G.; Changalucha, John; Christensen, Dirk L.; Grewal, Harleen; Martinussen, Torben; Krarup, Henrik; Witte, Daniel R; Andersen, Aase B.; Friis, Henrik. 2013. Diabetes is a strong predictor of mortality during tuberculosis treatment: a prospective cohort study among tuberculosis patients from Mwanza, Tanzania. Tropical medicine & international health. 18: 822-829. doi: 10.1111/tmi.12120
  • Faurholt-Jepsen, Daniel; Range, Nyagosya; PrayGod, George; Jeremiah, Kidola; Faurholt-Jepsen, Maria; Aabye, Martine G.; Grewal, Harleen; Changalucha, John; Witte, Daniel R; Andersen, Aase Bengaard; Friis, Henrik. 2013. BCG protects against tuberculosis irrespective of HIV status: a matched case-control study in Mwanza, Tanzania. Thorax. 68: 288-289. doi: 10.1136/thoraxjnl-2012-201971
  • Lodha, Rakesh; Mukherjee, Aparna; Saini, Deepak; Saini, Savita; Singh, Vineeta; Singh, Sarman; Grewal, Harleen; Kabra, Sushil Kabra. 2013. Role of the QuantiFERON (R)-TB Gold In-Tube test in the diagnosis of intrathoracic childhood tuberculosis. The International Journal of Tuberculosis and Lung Disease. 17: 1383-1388. doi: 10.5588/ijtld.13.0348
  • Mukherjee, Aparna; Singh, Sarman; Lodha, Rakesh; Singh, Varinder; Hesseling, Anneke C.; Grewal, Harleen; Kabra, Sushil K. 2013. Ambulatory gastric lavages provide better yields of mycobacterium tuberculosis than induced sputum in children with intrathoracic tuberculosis. The Pediatric Infectious Disease Journal. 32: 1313-1317. doi: 10.1097/INF.0b013e31829f5c58
  • Murthy, Maitreyi; Selvam, S; Jesuraj, N; Bennett, S; Doherty, M; Grewal, Harleen; Vaz, M; Vaz, Mario. 2013. TB Trials Study Group; Two-step tuberculin skin testing in school-going adolescents with initial 0-4 millimeter responses in a high tuberculosis prevalence setting in South India. PLoS ONE. 8: e71470. doi: 10.1371/journal.pone.0071470
  • Murthy, Maitreyi; Selvam, Sumithra; Jesuraj, Nelson; Bennett, Sean; Doherty, Mark; Grewal, Harleen; Vaz, Mario. 2013. Two-step tuberculin skin testing in school-going adolescents with initial 0-4 millimeter responses in a high tuberculosis prevalence setting in South India. PLoS ONE. 8. 10 pages. doi: 10.1371/journal.pone.0071470
  • Parashar, Deepak; Kabra, Sushil K.; Lodha, Rakesh; Singh, Varinder; Mukherjee, Aparna; Arya, Tina; Grewal, Harleen; Singh, Sarman. 2013. Does Neutralization of Gastric Aspirates from Children with Suspected Intrathoracic Tuberculosis Affect Mycobacterial Yields on MGIT Culture? Journal of Clinical Microbiology. 51: 1753-1756. doi: 10.1128/JCM.00202-13
  • Sivakumaran, Dhanasekaran; Jenum, Synne; Stavrum, Ruth; Ritz, Christian; Faurholt-Jepsen, Daniel; Kenneth, John; Vaz, Mario; Grewal, Harleen; Doherty, Timothy Mark. 2013. Identification of biomarkers for Mycobacterium tuberculosis infection and disease in BCG-vaccinated young children in Southern India. Genes and Immunity. 14: 356-364. doi: 10.1038/gene.2013.26
  • Andersen, Aase B.; Range, Nyagosya S.; Changalucha, John; PrayGod, George; Kidola, Jeremiah; Faurholt-Jepsen, Daniel; Krarup, Henrik; Grewal, Harleen; Friis, Henrik. 2012. CD4 lymphocyte dynamics in Tanzanian pulmonary tuberculosis patients with and without HIV co-infection. BMC Infectious Diseases. 12. 7 pages. doi: 10.1186/1471-2334-12-66
  • Mandalakas, Anna M.; Kirchner, H. Lester; Lombard, Carl; Walzl, Gerhard; Grewal, Harleen; Gie, Robert P.; Hesseling, Anneke C. 2012. Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection. The International Journal of Tuberculosis and Lung Disease. 16: 1033-1039. doi: 10.5588/ijtld.12.0027
  • PrayGod, George; Range, Nyagosya; Faurholt-Jepsen, Daniel; Kiddola, Jeremiah; Faurholt-Jepsen, Martine; Aabye, Martine G.; Jensen, Lotte; Jensen, Andreas V.; Grewal, Harleen; Magnussen, Pascal; Changalucha, John; Andersen, Aase Bengaard; Friis, Henrik. 2012. The effect of energy-protein supplementation on weight, body composition and handgrip strength among pulmonary tuberculosis HIV-co-infected patients: randomised controlled trial in Mwanza, Tanzania. British Journal of Nutrition. 107: 263-271. doi: 10.1017/S0007114511002832
  • Stavrum, Ruth; Valvatne, Håvard; Stavrum, Anne-Kristin; Riley, Lee W.; Ulvestad, Elling; Jonassen, Inge; Doherty, Timothy Mark; Grewal, Harleen. 2012. Mycobacterium tuberculosis Mcel protein complex initiates rapid induction of transcription of genes involved in substrate trafficking. Genes and Immunity. 13: 496-502. doi: 10.1038/gene.2012.24
  • Visser, Marianne E.; Stead, Michael; Walzl, Gerhard; Warren, Rob; Schomaker, Michael; Grewal, Harleen; Swart, Elizabeth C.; Maartens, Gary. 2012. Baseline Predictors of Sputum Culture Conversion in Pulmonary Tuberculosis: Importance of Cavities, Smoking, Time to Detection and W-Beijing Genotype. PLoS ONE. 7. 7 pages. doi: 10.1371/journal.pone.0029588
  • van Soelen, Nelda; Mandalakas, Anna M.; Kirchner, H. Lester; Walzl, Gerhard; Grewal, Harleen; Jacobsen, Marc; Hesseling, Anneke C. 2012. Effect of Ascaris Lumbricoides specific IgE on tuberculin skin test responses in children. BMC Infectious Diseases.
  • van Soelen, Nelda; Mandalakas, Anna M.; Kirchner, H. Lester; Walzl, Gerhard; Grewal, Harleen; Jacobsen, Marc; Hesseling, Anneke C. 2012. Effect of Ascaris Lumbricoides specific IgE on tuberculin skin test responses in children in a high-burden setting: a cross-sectional community-based study. BMC Infectious Diseases. 12. 8 pages. doi: 10.1186/1471-2334-12-211
  • PrayGod, George; Range, Nyagosya; Faurholt-Jepsen, Daniel; Jeremiah, Kidola; Faurholt-Jepsen, Maria; Aabye, Martine G.; Jensen, Lotte; Jensen, Anders Gadegaard; Grewal, Harleen; Magnussen, Pascal; Changalucha, John; Andersen, Aase Bengaard; Friis, Henrik. 2011. Daily multi-micronutrient supplementation during tuberculosis treatment increases weight and grip strength among HIV-uninfected but not HIV-Infected patients in Mwanza, Tanzania. Journal of Nutrition. 141: 685-691. doi: 10.3945/jn.110.131672
  • PrayGod, George; Range, Nyagosya; Faurholt-Jepsen, Daniel; Jeremiah, Kidola; Faurholt-Jepsen, Maria; Aabye, Martine G.; Jensen, Lotte; Jensen, Andreas V.; Grewal, Harleen; Magnussen, Pascal; Changalucha, John; Andersen, Aase Bengaard; Friis, Henrik. 2011. Weight, body composition and handgrip strength among pulmonary tuberculosis patients: a matched cross-sectional study in Mwanza, Tanzania. Transactions of the Royal Society for Tropixcal Medicine and Hygiene. 105: 140-147. doi: 10.1016/j.trstmh.2010.11.009
  • Rajaraman, Divya; Jesuraj, Nelson; Geiter, Lawrence; Bennett, Sean; Grewal, Harleen; Vaz, Mario. 2011. How participatory is parental consent in low literacy rural settings in low income countries? Lessons learned from a community based study of infants in South India. BMC Medical Ethics. 12. 9 pages. doi: 10.1186/1472-6939-12-3
  • Stavrum, Ruth; Stavrum, Anne-Kristin; Valvatne, Håvard; Riley, Lee W.; Ulvestad, Elling; Jonassen, Inge; Assmus, Jørg; Doherty, T. Mark; Grewal, Harleen. 2011. Modulation of transcriptional and inflammatory responses in murine macrophages by the mycobacterium tuberculosis mammalian cell entry (Mce) 1 complex. PLoS ONE. 6. 11 pages. doi: 10.1371/journal.pone.0026295
  • Syre, Heidi; Grewal, Harleen. 2011. Isoniazid and rifampicin resistance-associated mutations in Mycobacterium tuberculosis isolates from Yangon, Myanmar: implications for rapid molecular testing-authors' response. Journal of Antimicrobial Chemotherapy. 66: 687-687. doi: 10.1093/jac/dkq514
  • Visser, Marianne E.; Grewal, Harleen; Swart, Elizabeth C.; Dhansay, Muhammed A.; Walzl, Gerhard; Swanevelder, Sonja; Lombard, Carl; Maartens, Gary. 2011. The effect of vitamin A and zinc supplementation on treatment outcomes in pulmonary tuberculosis: a randomized controlled trial. American Journal of Clinical Nutrition. 93: 93-100. doi: 10.3945/ajcn.110.001784
  • du Preez, Karen; Mandalakas, Anna M.; Kirchner, H. Lester; Grewal, Harleen; Schaaf, H. Simon; van Wyk, Susan S.; Hesseling, Anneke C. 2011. Environmental tobacco smoke exposure increases Mycobacterium tuberculosis infection risk in children. The International Journal of Tuberculosis and Lung Disease. 15: 1490-1496. doi: 10.5588/ijtld.10.0759
  • Jeremiah, Kidola; PrayGod, George; Faurholt-Jepsen, Daniel; Range, Nyagosya; Andersen, Aase B.; Grewal, Harleen; Friis, Henrik. 2010. BCG vaccination status may predict sputum conversion in patients with pulmonary tuberculosis: a new consideration for an old vaccine? Thorax. 65: 1072-1076. doi: 10.1136/thx.2010.134767
  • Syre, Heidi; Øvreås, Kristi; Grewal, Harleen. 2010. Determination of the susceptibility of Mycobacterium tuberculosis to pyrazinamide in liquid and solid media assessed by a colorimetric nitrate reductase assay. Journal of Antimicrobial Chemotherapy. 65: 704-712. doi: 10.1093/jac/dkp506
  • Detjen, Anne K.; Loebenberg, L.; Grewal, Harleen; Stanley, Kim; Gutschmidt, Andrea; Krüger, Carsten; Du Plessis, Nelita; Kidd, Martin; Beyers, Neel; Walzl, G.; Hesseling, Anneke C. 2009. Short-Term Reproducibility of a Commercial Interferon Gamma Release Assay. Clinical and Vaccine Immunology. 16: 1170-1175. doi: 10.1128/CVI.00168-09
  • Phyu, Sabai; Stavrum, Ruth M Støbakk; Lwin, Thandar; Svendsen, Øyvind Sverre; Ti, Ti; Grewal, Harleen. 2009. Predominance of Mycobacterium tuberculosis EAI and Beijing Lineages in Yangon, Myanmar. Journal of Clinical Microbiology. 47: 1283-1283. doi: 10.1128/JCM.00311-09
  • Phyu, Sabai; Stavrum, Ruth; Lwin, Thandar; Svendsen, Øyvind Sverre; Ti, Ti; Grewal, Harleen. 2009. Predominance of mycobacterium tuberculosis EAI and Beijing lineages in Yangon, Myanmar. Journal of Clinical Microbiology. 47: 335-344. doi: 10.1128/JCM.01812-08
  • Stavrum, Ruth M Støbakk; Mphahlele, Matsie Theodora; Øvreås, Kristi; Muthivhi, Tshilidzi; Fourie, Bernard; Weyer, Karin; Grewal, Harleen. 2009. High diversity of Mycobacterium tuberculosis genotypes in South Africa and preponderance of mixed infections among ST53 isolates. Journal of Clinical Microbiology. 47: 1848-1856. doi: 10.1128/JCM.02167-08
  • Stavrum, Ruth M Støbakk; Myneedu, Vithal Prasad; Arora, Virendra K.; Ahmed, Niyaz; Grewal, Harleen. 2009. In-depth molecular characterization of Mycobacterium tuberculosis from New Delhi--predominance of drug resistant isolates of the 'modern' (TbD1) type. PLoS ONE. 4. doi: 10.1371/journal.pone.0004540
  • Syre, Heidi; Myneedu, Vithal Prasad; Arora, Virendra K.; Grewal, Harleen. 2009. Direct detection of mycobacterial species in pulmonary specimens by two rapid amplification tests, the gen-probe amplified mycobacterium tuberculosis direct test and the genotype mycobacteria direct test. Journal of Clinical Microbiology. 47: 3635-3639. doi: 10.1128/JCM.00411-09
  • Valvatne, Håvard; Syre, Heidi; Kross, Martijn; Ti, Ti; Phyu, Sabai; Grewal, Harleen. 2009. Isoniazid and rifampicin resistance-asTisociated mutations in Mycobacterium tuberculosis isolates from Yangon, Myanmar: implications for rapid molecular testing. Journal of Antimicrobial Chemotherapy. 64: 694-701. doi: 10.1093/jac/dkp292
  • Grewal, Harleen; Gupta, Swati; Singh, Sarman. 2008. Opportunistic pathogens in AIDS: trends, diagnosis and priorities. Expert Review of Anti-infective Therapy. 6: 163-166. doi: 10.1586/14787210.6.2.163
  • Hembre, Berit Sofie Hustad; Briles, David E; Grewal, Harleen; Strand, Tor A. 2008. Effect of high dose oral zinc in mice with severe infection with Streptococcus pneumoniae. Scandinavian Journal of Infectious Diseases. 40: 363-367. doi: 10.1080/00365540701716833
  • Mphahlele, Matsie; Syre, Heidi; Valvatne, Håvard; Stavrum, Ruth; Mannsåker, Turid; Muthivhi, Tshilidzi; Weyer, Karin; Fourie, P Bernard; Grewal, Harleen MS. 2008. Pyrazinamide resistance among South African multidrug-resistant Mycobacterium tuberculosis isolates. Journal of Clinical Microbiology. 46: 3459-3464. doi: 10.1128/JCM.00973-08
  • Stavrum, Ruth M Støbakk; Valvatne, Håvard; Bø, Trond Hellem; Jonassen, Inge; Hinds, Jason; Butcher, Philip; Grewal, Harleen. 2008. Genomic Diversity among Beijing and non-Beijing Mycobacterium tuberculosis Isolates from Myanmar. PLoS ONE. 3: e1973. doi: 10.1371/journal.pone.0001973
  • Syre, Heidi; Valvatne, H.; Sandven, P.; Grewal, H.M.S. 2006. Evaluation of the nitrate-based colorimetric method for testing the susceptibility of Mycobacterium tuberculosis to streptomycin and ethambutol in liquid cultures. Journal of Antimicrobial Chemotherapy. 57: 987-991. doi: 10.1093/jac/dkl054
  • Dahle, Ulf R; Nordtvedt, Sally G; Winje, Brita Askeland; Mannsåker, Turid; Heldal, Einar; Sandven, Per; Grewal, Harleen; Grewal, Harleen; Caugant, Dominique A. 2005. Tuberculosis in contacts need not indicate disease transmission. Thorax. 60: 136-137.
  • Phyu, Sabai; Lwin, Thandar; Maung, Win; Ti, Ti; Mar, Win; Shein, San; Grewal, Harleen. 2005. Drug-resistant tuberculosis in Yangon, Myanmar. Scandinavian Journal of Infectious Diseases. 37: 846-851. doi: 10.1080/00365540500265065
  • Valvatne, Håvard; Steinsland, Hans; Grewal, Harleen; Mølbak, Kåre; Vuust, Jens; Sommerfelt, Halvor. 2004. Identification and molecular characterization of the gene encoding coli surface antigen 20 of enterotoxigenic Escherichia coli. FEMS Microbiology Letters. 239: 131-138. doi: doi:10.1016/j.femsle.2004.08.0
  • Vetvik, H; Grewal, Harleen; Haugen, I. L.; Åhren, C; Haneberg, B. 1998. Mucosal antibodies can be measured in air-dried samples of saliva and feces. JIM - Journal of Immunological Methods. 215: 163-172.
  • Vetvik, H; Grewal, Harleen; Haugen, I.L.; Åhren, C; Haneberg, B. 1998. Mucosal antibodies can be measured in air-dried samples of saliva and feces. JIM - Journal of Immunological Methods. 215: 163-172.
  • Grewal, Harleen; Valvatne, Håvard; Bhan, M. K.; van Dijk, L; Gaastra, W.; Sommerfelt, Halvor. 1997. A new fimbrial putative colonization factor, CS19 in human enterotoxigenic <I>Escherichia coli</I>. Infection and Immunity. 65: 507-13.
  • Grewal, Harleen; Valvatne, Håvard; Bhan, M. K.; van Dijk, Linda; Gaastra, W.; Sommerfelt, Halvor. 1997. A new putative colonization factor, CS19, of human enterotoxigenic Escherichia coli. Infection and Immunity. 65: 507-513.
  • Halvorsen, T.; Valvatne, Håvard; Grewal, Harleen; Gaastra, W.; Sommerfelt, Halvor. 1997. Expression of colonization factor antigen I fimbriae by enterotoxigenic Escherichia coli; influence by growth conditions and a recombinant positive regulatory gene. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 105: 247-254.
  • Halvorsen, T.; Valvatne, Håvard; Grewal, Harleen; Gaastra, W.; Sommerfelt, Halvor. 1997. Expression of colonization factor antigen I by enterotoxigenic <I>Escherichia coli</I>; influence of growth conditions and a recombinant positive regulatory gene. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 105: 247-254.
  • Helander, A.; Grewal, Harleen; Gaastra, W.; Svennerholm, A-M. 1997. Detection and characterization of the coli surface antigen 6 of enterotoxigenic <I>Escherichia coli</I> by using monoclonal antibodies. Journal of Clinical Microbiology. 35: 867-872.
  • Helander, A.; Grewal, Harleen; Gaastra, W.; Svennerholm, A-M. 1997. Detection and characterisation of the coli surface antigen 6 of enterotoxigenic Escherichia coli by using monoclonal antibodies. Journal of Clinical Microbiology. 35: 867-872.
  • Grewal, Harleen; Hellander, A; Svennerholm, A-M.; Bhan, MK; Gaastra, W; Sommerfelt, Halvor. 1994. Genotypic and phenotypic identification of coli surface antigen 6-positive enterotoxigenic Escherichia coli. Journal of Clinical Microbiology. 32: 1295-1301.
  • Grewal, Harleen; Gaastra, W.; Svennerholm, A-M.; Røli, J.; Sommerfelt, Halvor. 1993. Induction of Colonization Factor Antigen I and Coli Surface Antigen 4 of enterotoxigenic Escherichia coli. Vaccine. 11: 221-226.
  • Sommerfelt, Halvor; Grewal, Harleen; Gaastra, W.; Svennerholm, A-M.; Bhan, M. K. 1992. Use of nonradioactive DNA Hybridization for the identification of enterotoxigenic Escherichia coli harboring genes for colonization factor antigen/1, coli surface antigen 4 and putative colonization factor 0166. Journal of Clinical Microbiology. 30: 1823-1828.
  • Sommerfelt, Halvor; Grewal, Harleen; Svennerholm, A-M.; Gaastra, W.; Bhan, M. K. 1992. Colonization factor antigen I, coli surface antigen 4 and putative colonization factor 0166 of enterotoxigenic Escherichia coli are genetically related. Vaccine. 10: 289-289.
  • Sommerfelt, Halvor; Grewal, Harleen; Svennerholm, A-M.; Gaastra, W.; Flood, P.; Viboud, G.; Bhan, M. K. 1992. Genetic relationship of putative colonization factor 0166 to colonization factor antigen I and coli surface antigen 4 of enterotoxigenic Escherichia coli. Infection and Immunity. 60: 3799-3806.
  • Sommerfelt, Halvor; Grewal, Harleen; Gaastra, W.; Bhan, M. K.; Svennerholm, A-M.; Kalland, Karl-Henning; Asphaug, V.; Aasland, Rein; Bjorvatn, B. 1991. Presence of cfaD-homologous sequences and expression of coli surface antigen 4 on enterotoxigenic Escherichia coli; relevance for diagnostic procedures. Microbial Pathogenesis. 11: 297-304.
Reports and theses
  • Grewal, Harleen. 1995. Colonization factors of enterotoxigenic Escerichia coli: detection and expression (dr. med.). Dr.med.. -. Centre for International Health, Laboratory for Biotechnology and Department of Microbiology and Immunology, T. 1 pages.
Book sections
  • Carriere, Heidi Syre; Grewal, Harleen. 2011. Immunology of Tubercolosis: Basic Aspects and Relevance for Immunodiagnostic Tests. 7, pages 66-89. In:
    • Seth, Vimlesh; Kabra, SK. 2011. Essentials of Tuberculosis in Children. 670 pages. ISBN: 978-93-5025-252-9.

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