Jan
Haavik
Professor
Visit Address:
Jonas Lies vei 91
5020 Bergen
Postal Address:
Postboks 7800
5020 Bergen
Phone:
+47 55 58 64 32
+47 55 58 64 51
E-mail:
Journal articles
- 2014. Functional studies of tyrosine hydroxylase missense variants reveal distinct patterns of molecular defects in dopa-responsive dystonia. Human Mutation. 35: 880-890. doi: 10.1002/humu.22565
- 2014. Autoantibodies targeting neurotransmitter biosynthetic enzymes in attention-deficit/hyperactivity disorder (ADHD). European Child and Adolescent Psychiatry. 23: 115-117. doi: 10.1007/s00787-013-0429-3
- 2014. Modelling cellular signal communication mediated by phosphorylation dependent interaction with 14-3-3 proteins. FEBS Letters. 588: 92-98. doi: 10.1016/j.febslet.2013.11.012
- 2014. Phosphorylation dependence and stoichiometry of the complex formed by tyrosine hydroxylase and 14-3-3γ. Molecular & Cellular Proteomics. 13: 2017-2030. doi: 10.1074/mcp.M113.035709
- 2014. Decreased serum levels of adiponectin in adult attention deficit hyperactivity disorder. Psychiatry Research. 216: 123-130. doi: 10.1016/j.psychres.2014.01.025
- 2013. Autoantibodies against aromatic amino acid hydroxylases in patients with autoimmune polyendocrine syndrome type 1 target multiple antigenic determinants and reveal regulatory regions crucial for enzymatic activity. Immunobiology. 218: 899-909. doi: 10.1016/j.imbio.2012.10.006
- 2013. Long-term efficacy and safety of treatment with stimulants and atomoxetine in adult ADHD: A review of controlled and naturalistic studies. European Neuropsychopharmacology. 23: 508-527. doi: 10.1016/j.euroneuro.2012.07.016
- 2013. Personality traits and comorbidity in adults With ADHD. Journal of Attention Disorders. doi: 10.1177/1087054713511986
- 2013. DISC1 in adult ADHD patients: An association study in two European samples. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 162B: 227-234. doi: 10.1002/ajmg.b.32136
- 2013. Functional properties of rare missense variants of human CDH13 found in adult attention deficit/hyperactivity disorder (ADHD) patients. PLoS ONE. 8. 9 pages. doi: 10.1371/journal.pone.0071445
- 2012. Adults with attention-deficit/hyperactivity disorder - a diffusion-tensor imaging study of the corpus callosum. Psychiatry Research : Neuroimaging. 201: 168-173. doi: 10.1016/j.pscychresns.2011.08.005
- 2012. The genetics of attention deficit/hyperactivity disorder in adults, a review. Molecular Psychiatry. 17: 960-987. doi: 10.1038/mp.2011.138
- 2012. Set-shifting in adults with ADHD. Journal of the International Neuropsychological Society. 18: 728-737. doi: 10.1017/S1355617712000355
- 2012. Pre- and perinatal risk factors in adults with attention-deficit/hyperactivity disorder. Biological Psychiatry. 71: 474-481. doi: 10.1016/j.biopsych.2011.11.013
- 2012. DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder. PLoS ONE. 7. 12 pages. doi: 10.1371/journal.pone.0035424
- 2012. The negative impact of attention-deficit/hyperactivity disorder on occupational health in adults and adolescents. International Archives of Occupational and Environmental Health. 85: 837-847. doi: 10.1007/s00420-012-0794-0
- 2012. The impact of cyclothymic temperament in adult ADHD. Journal of Affective Disorders. 142: 241-247. doi: 10.1016/j.jad.2012.04.034
- 2011. Glutamate cysteine ligase (GCL) and self reported depression: An association study from the HUNT. Journal of Affective Disorders. 131: 207-213. doi: 10.1016/j.jad.2010.12.019
- 2011. Adults with attention-deficit/hyperactivity disorder - a brain magnetic resonance spectroscopy study. Frontiers in Psychiatry. 2. 8 pages. Published 2011-11-23. doi: 10.3389/fpsyt.2011.00065
- 2011. Cognitive control in adults with attention-deficit/hyperactivity disorder. Psychiatry Research. 188: 406-410. doi: 10.1016/j.psychres.2011.04.014
- 2011. Adult attention deficit hyperactivity disorder is associated with asthma. BMC Psychiatry. 11. 7 pages. doi: 10.1186/1471-244X-11-128
- 2011. Adult attention deficit hyperactivity disorder is associated with migraine headaches. European Archives of Psychiatry and Clinical Neuroscience. 261: 595-602. doi: 10.1007/s00406-011-0203-9
- 2011. Maternal genotypes as predictors of offspring mental health; the next frontier of genomic medicine? Future Neurology. 6: 731-743. doi: 10.2217/FNL.11.54
- 2011. The 14-3-3 proteins in regulation of cellular metabolism. Seminars in Cell and Developmental Biology. 22: 713-719. doi: 10.1016/j.semcdb.2011.08.008
- 2011. No association between the serotonin transporter gene polymorphism 5-HTTLPR and cyclothymic temperament as measured by TEMPS-A. Journal of Affective Disorders. 129: 308-312. doi: 10.1016/j.jad.2010.08.028
- 2011. Bipolar disorder risk alleles in adult ADHD patients. Genes, Brain and Behavior. 10: 418-423. doi: 10.1111/j.1601-183X.2011.00680.x
- 2011. Attention Network Test in adults with ADHD - the impact of affective fluctuations. Behavioral and Brain Functions. 7. 8 pages. doi: 10.1186/1744-9081-7-27
- 2011. DIRAS2 is Associated with Adult ADHD, Related Traits, and Co-Morbid Disorders. Neuropsychopharmacology. 36: 2318-2327. doi: 10.1038/npp.2011.120
- 2011. Exploring DRD4 and its interaction with SLC6A3 as possible risk factors for adult ADHD: a meta-analysis in four european populations. American Journal of Medical Genetics. 156B: 600-612. doi: 10.1002/ajmg.b.31202
- 2011. Association of GTP-binding protein Di-Ras2 (DIRAS2) with attention-deficit/hyperactivity disorder. European Neuropsychopharmacology. 21: S5-S5.
- 2010. A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication. Molecular Psychiatry. 15: 1053-1066. doi: 10.1038/mp.2010.6
- 2010. Decorin accumulation contributes to the stromal opacities found in congenital stromal corneal dystrophy. Investigative Ophthalmology and Visual Science. 51: 5578-5582. doi: 10.1167/iovs.09-4933
- 2010. Effect of pharmacological chaperones on brain tyrosine hydroxylase and tryptophan hydroxylase 2. Journal of Neurochemistry. 114: 853-863. doi: 10.1111/j.1471-4159.2010.06821.x
- 2010. Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD. Neuropsychopharmacology. 35: 656-664. doi: 10.1038/npp.2009.170
- 2010. Clinical assessment and diagnosis of adults with attention-deficit/hyperactivity disorder. Expert Review of Neurotherapeutics. 10: 1569-1580. doi: doi:10.1586/ern.10.149
- 2010. Bipolar symptoms in adult attention-deficit/hyperactivity disorder: A cross-sectional study of 510 clinically diagnosed patients and 417 population-based controls. Journal of Clinical Psychiatry. 71: 48-57. doi: 10.4088/JCP.08m04722ora
- 2010. Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production. Archives of General Psychiatry. 67: 1033-1043.
- 2010. Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations. American Journal of Medical Genetics. 153B: 1008-1015. doi: 10.1002/ajmg.b.31067
- 2010. An international multicenter association study of the serotonin transporter gene in persistent ADHD. Genes, Brain and Behavior. 9: 449-458. doi: 10.1111/j.1601-183X.2010.00567.x
- 2010. PHARMACOLOGICAL CHAPERONES FOR THE AROMATIC AMINO ACID HYDROXYLASES. Journal of Inherited Metabolic Disease. 33: S163-S163.
- 2010. Functional studies of candidate genes involved in ADHD. European Psychiatric Review. 3: 44-46.
- 2010. Meta-analysis of brain-derived neurotrophic factor p.Val66Met in adult ADHD in four European populations. American Journal of Medical Genetics. 153B: 512-523. doi: 10.1002/ajmg.b.31008
- 2010. FUNCTIONAL STUDIES OF DISEASE-RELATED VARIANTS IN HUMAN TRYPTOPHAN HYDROXYLASE 1 AND 2. Journal of Inherited Metabolic Disease. 33: S165-S165.
- 2010. A genome-wide association study of bipolar disorder and comorbid migraine. Genes, Brain and Behavior. 9: 673-680. doi: 10.1111/j.1601-183X.2010.00601.x
- 2010. A genetic study of bipolar disorder and co-morbid migraine. Bipolar Disorders. 12: 62-62.
- 2009. Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen. Proceedings of the National Academy of Science of the United States of America. 106: 4396-4411. doi: 10.1073/pnas.0809986106
- 2009. The dopamine system in adult ADHD - findings from the IMpACT study. European Neuropsychopharmacology. 19: S186-S186.
- 2009. From childhood to adulthood - testing the IMAGE candidates in IMpACT. European Neuropsychopharmacology. 19: S185-S185.
- 2009. Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD. Neuropsychopharmacology. 35: 656-664. doi: 10.1038/npp.2009.170
- 2009. From synthesis to uptake - serotonergic genes in adult ADHD. European Neuropsychopharmacology. 19: S186-S186.
- 2009. Association between Catechol O-methyltransferase (COMT) haplotypes and severity of hyperactivity symptoms in Adults. American Journal of Medical Genetics. 150B: 403-410. doi: 10.1002/ajmg.b.30831
- 2009. Occupational outcome in adult ADHD:impact of symptom profile, comorbid psychiatric problems, and treatment: a cross-sectional study of 414 clinically diagnosed adult ADHD patients. Journal of Attention Disorders. 13: 175-187. doi: 10.1177/1087054708329777
- 2009. Three-way interaction between 14-3-3 proteins, the N-terminal region of tyrosine hydroxylase and negatively charged membranes. Journal of Biological Chemistry. 284: 32758-32769. doi: 10.1074/jbc.M109.027706
- 2009. Functional Properties of Missense Variants of Human Tryptophan Hydroxylase 2. Human Mutation. 30: 787-794. doi: 10.1002/humu.20956
- 2009. Case-control study of six genes asymmetrically expressed in the two cerebral hemispheres: association of BAIAP2 with attention-deficit/hyperactivity disorder. Biological Psychiatry. 66: 926-934. doi: 10.1016/j.biopsych.2009.06.024
- 2009. Tryptophan as an evolutionarily conserved signal to brain serotonin: molecular evidence and psychiatric implications. World Journal of Biological Psychiatry. 10: 258-268. doi: 10.3109/15622970701513764
- 2008. Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5 '-region are associated with bipolar affective disorder. Human Molecular Genetics. 17: 87-97. doi: 10.1093/hmg/ddm286
- 2008. Human tryptophan hydroxylases; molecular properties and clinical implications. Fundamental & Clinical Pharmacology. 22: 113-113.
- 2008. Mutations in human monoamine-related neurotransmitter pathway genes. Human Mutation. 29: 891-902. doi: 10.1002/humu.20700
- 2008. Genetic Analyses of Dopamine Related Genes in Adult ADHD Patients Suggest an Association With the DRD5-Microsatellite Repeat, But Not With DRD4 or SLC6A3 VNTRs. American Journal of Medical Genetics. 147B: 1470-1475. doi: 10.1002/ajmg.b.30662
- 2008. A loss-of-function mutation in tryptophan hydroxylase 2 segregating with attention-deficit/hyperactivity disorder. Molecular Psychiatry. 13: 365-367. doi: 10.1038/sj.mp.4002152
- 2008. Oxygen dependence of tyrosine hydroxylase. Amino Acids. 34: 455-464. doi: 10.1007/s00726-007-0547-7
- 2008. Endogenous tetrahydroisoquinolines associated with Parkinson's disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines. The FEBS Journal. 275: 2109-2121. doi: 10.1111/j.1742-4658.2008.06365.x
- 2008. Tetrahydrobiopterin shows chaperone activity for tyrosine hydroxylase. Journal of Neurochemistry. 106: 672-681. doi: 10.1111/j.1471-4159.2008.05423.x
- 2008. Tetrahydrobiopterin shows chaperone activity for tyrosine hydroxylase. Journal of Inherited Metabolic Disease. 31: 138-138.
- 2008. Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2. Journal of Neurochemistry. 100: 1648-1657. doi: 10.1111/j.1471-4159.2006.04290.x
- 2008. Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding. Biochemical Journal. 410: 195-204. doi: 10.1042/BJ20071033
- 2007. Epitope mapping of human aromatic L-amino acid decarboxylase. Biochemical and Biophysical Research Communications - BBRC. 353: 692-698. doi: 10.1016/j.bbrc.2006.12.080
- 2007. Epitope mapping of human aromatic L-amino acid decarboxylase. Scandinavian Journal of Immunology. 65: 592-592.
- 2007. A systematic intervention to improve patient information and satisfaction in a psychiatric emergency unit. Nordic Journal of Psychiatry. 61: 213-218. doi: 10.1080/08039480701352579
- 2007. Selectivity and affinity determinants for ligand binding to the aromatic amino acid hydroxylases. Current Medicinal Chemistry. 14: 455-467. doi: 10.2174/092986707779941023
- 2007. Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2. Journal of Neurochemistry. 100: 1648-1657. doi: 10.1111/j.1471-4159.2006.04290.x
- 2006. The regulatory phosphorylated serine in full-length nitrate reductase is necessary for optimal binding to a 14-3-3 protein. Plant Science. 170: 394-398.
- 2006. The regulatory phosphorylated serine in full-length nitrate reductase is necessary for optimal binding to a 14-3-3 protein. Plant Science. 170: 394-398. doi: 10.1016/j.plantsci.2005.09.004
- 2006. Characterization og wild-type and mutant forms of human trytopan hydroxylase 2. Journal of Neurochemistry. 10 pages. doi: 10.1111/j.1471-4159.2006.04290.x
- 2005. An oxygraphic method for determining kinetic properties and catalytic mechanism of aromatic amino acid hydroxylases. Analytical Biochemistry. 343: 100-105. doi: 10.1016/j.ab.2005.04.043
- 2005. Biochemical characterization of mutant aromatic amino acid hydroxylases implicated in psychiatric disorders. American Journal of Medical Genetics. 138B.
- 2005. Molecular mechanisms of action of antidepressants (Norwegian review). NBS-nytt. 29: 23-29.
- 2005. Different properties of the central and peripheral forms of human tryptophan hydroxylase. Journal of Neurochemistry. 92: 311-320.
- 2005. Stimulation of hepatic phenylalanine hydroxylase activity but not Pah-mRNA expression upon oral loading of tetrahydrobiopterin in normal mice. Molecular Genetics and Metabolism. 86: S153-S155. doi: 10.1016/j.ymgme.2005.09.015
- 2005. Effects of mutations in human tryptophan hydroxylases associated with altered monoaminergic neurotransmission. Journal of Neurochemistry. 94.
- 2004. Different stabilities and denaturation pathways for structurally related aromatic amino acid hydroxylases. FEBS Letters. 565: 155-159.
- 2004. Expression and purification of human tryptophan hydroxylase from Escherichia coli and Pichia pastoris. Protein Expression and Purification. 33: 185-194.
- 2004. Tetrahydrobiopterin binding to aromatic amino acid hydroxylases. Ligand recognition and specificity. Journal of Medicinal Chemistry. 47: 5962-5971.
- 2002. Regulation of tyrosine hydroxylase by stress activated protein kinases. Journal of Neurochemistry. 83: 775-783.
- 2002. Phosphorylation of tyrosine hydroxylase in isolated mice adrenal glands. Annals of the New York Academy of Sciences. 971: 66-68.
- 2002. Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin. Biochemistry. 41: 12569-12574.
- 2001. A phenylalanine hydroxylase amino acid polymorphism with implications for molecular diagnostics. Molecular Genetics and Metabolism. 73: 280-284.
- 2001. Hvorfor gir mutasjoner sykdom ? Et proteinkjemisk perspektiv. Tidsskrift for Den norske legeforening. 121: 2717-2720.
- 2001. Interaction of phosphorylated tyrosine Hydroxylase with 14-3-3 proteins. Evidence for a phosphoserine 40 dependent association. Journal of Neurochemistry. 77: 1097-1107.
- 2001. A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosynthesis. Current Medicinal Chemistry. 8: 1077-91 + cover.
- 2001. The structure of tryptophan hydroxylase structure of tryptophan hydroxylase enzyme substrate complexes as determined by NMR spectroscopy and molecular modeling. Pteridines. 12: 61-62.
- 2001. Conformation of the substrate and pterin cofactor bound to human tryptophan hydroxylase. Important role of Phe313 in substrate specificity. Biochemistry. 40: 15591-15601.
- 2000. A kinetic and conformational study on the interaction of tetrahydropteridines with tyrosine hydroxylase. Biochemistry. 39: 13676-13686.
- 2000. Pteridin dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 85: 2944-2950.
- 2000. Pteridine-dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 85: 2944-2950.
- 2000. Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I. Biochemical and Biophysical Research Communications - BBRC. 267: 456-461.
- 2000. Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I. Biochemical and Biophysical Research Communications - BBRC. 267: 456-461.
- 2000. Inhibition of aromatic 1-amino acid decarboxylase by human autoantibodies. Clinical and Experimental Immunology. 120: 420-423.
- 2000. Inhibition of aromatic L-amino acid decarboxylase activity by human autoantibodies. Clinical and Experimental Immunology. 120: 420-423.
- 1999. Urea-induced denaturation of human phenylalanine hydroxylase. Journal of Biological Chemistry. 274: 33251-33258.
- 1999. Urea-induced denaturation of human phenylalanine hydroxylase. Journal of Biological Chemistry. 274: 33251-33258.
- 1999. Iron coordination geometry in full-length, truncated, and dehydrated forms of human tyrosine hydroxylase studied by Mossbauer and X-ray spectroscopy. Journal of Biological Inorganic Chemistry. 4: 223-231.
- 1999. Partition Coefficients and Interfacial Activity for Polar Components in Oil/Water Model Systems. Journal of Colloid and Interface Science. 212: 33-41.
- 1999. Effect of polar organic components on wettability as studied by adsorption and contact angles. Journal of Petroleum Science and Engineering. 24: 131-144.
- 1999. Mitogen and stress activated protein kinase signaling pathways: emerging functions in the nervous system. Recent Research Developments in Neurochemistry. 2: 71-89.
- 1999. MAP and SAP kinase signaling pathways: emerging functions in the nervous system. Recent Research Developmental in Neurochemistry. 2: 71-89.
- 1998. Human tyrosine hydroxylase isoforms. Inhibition by excess tetrahydropterin and unusual behavior of isoform 3 after cAMP-dependent protein kinase phosphorylation. Journal of Biological Chemistry. 273: 10196-102011. Published 1998-04-24.
- 1998. Identification of tryptophan hydroxylase as an intestinal autoantigen. The Lancet. 352: 279-283.
- 1998. Identification of tryptophan hydroxylase as an intestinal autoantigen. The Lancet. 352: 279-283.
- 1998. Tyrosine hydroxylase and Parkinsons's disease. Molecular Neurobiology. 16: 285-309.
- 1998. The effect of phosphorylation at Ser-40 on the structure and thermal stability of tyrosine hydroxylase. Advances in Pharmacology. 42: 15-18.
- 1997. Tetrahydropteridines as photoaffinity probes of aromatic amino acid monooxygenases. Pteridines. 8: 137-138.
- 1997. Spontaneous mutation frequencies and spectra in p53 (+/+) and p53 (-/-)mice: a test of the "guardian of the genome" hypothesis in the Big Blue transgenic mouse mutation detection system. Mutation research. 379: 13-20.
- 1997. Crystallization and preliminary diffraction analysis of a truncated homodimer of human phenylalanine hydroxylase. FEBS Letters. 406: 171-174.
- 1997. L-DOPA is a substrate for tyrosine hydroxylase. Journal of Neurochemistry. 69: 1720-1728.
- 1997. Generation of reactive oxygen species by tyrosine hydroxylase-a possible contribution to the degeneration of dopaminergic neurons. Journal of Neurochemistry. 68: 328-332.
- 1997. The effect of phosphorylation at Ser-40 on the structure and thermal stability of tyrosine hydroxylase. Advances in Pharmacology. 42: 15-18.
- 1997. Participation of a stress-activated MAP kinase cascade in the activation of tyrosine hydroxylase in chromaffin cells. European Journal of Biochemistry. 247: 1180-1189.
- 1996. Characterization of a novel pterin intermediate formed in the catalytic cycle of tyrosine hydroxylase. Biochemical Journal. 319: 947-951.
- 1996. Bidirectional Dideoxy Fingerprinting (Bi-ddF): Rapid and efficient screening for mutations in the Big Blue Transgenic Mouse Mutation detection system. BioTechniques. 20: 988-994.
- 1996. Structure-function relationship in human phenylalanine hydroxylase . Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme. European Journal of Biochemistry. 242: 813-821.
- 1996. Conformational properties and stability of tyrosine hydroxylase studied by infrared spectroscopy. Effect of iron/catecholamine binding and phosphorylation. Journal of Biological Chemistry. 271: 19737-19742.
- 1996. Characterization of the iron environment in human tyrosine hydroxylase, using M#"ossbauer-, EPR-, and EXAFS-spectroscopy. Conf Proc Ital Phys Soc. 50: 819-822.
- 1996. A M@øssbauer, EPR and XAFS study of the iron environment in recombinant human tyrosine hydroxylase. European Journal of Biochemistry. 241: 432-439.
- 1996. Spontaneous mutation in Big Blue Transgenic mice: Analysis of age, gender and tissue type. Environmental and Molecular Mutagenesis. 28: 299-312.
- 1996. Mutation frequencies but not mutant frequencies in Big Blue Mice fit a poisson distribution. Environmental and Molecular Mutagenesis. 28: 414-417.
- 1995. Synthesis of 6-azidomenthyl-5,6,7,8-tetrahydropterin. Photodegradation products and cofactor properties for aromatic amino acid monooxygenases. Pteridines. 6: 153-159.
- 1995. Tryptophan fluorescence of human phenylalanine hydroxylase produced in Escherichia coli. Biochemistry. 34: 11790-11799.
- 1995. Tryptophan fluorescence of human phenylalanine hydroxylase expressed in Escherichia coli. Biochemistry. 34: 11790-11799.
- 1995. XAFS of human tyrosine hydroxylase. Physica. B, Condensed matter. 209: 717-718.
- 1995. Resonance Raman studies of catecholate and phenolate complexes of recombinant human tyrosine hydroxylase. Biochemistry. 34: 5504-5510.
- 1995. p53 wild-type and p53 nullizygous Big Blue transgenic mice have similar frequencies and patterns of observed mutation in liver, spleen and brain. Oncogene. 11: 263-270.
- 1995. Mayo Clinic - et medisinsk Mekka i Midtvesten. Tidsskrift for Den norske legeforening. 115: 2678-2679.
- 1993. Conformation and interaction of phenylalanine with the divalent cation at the active site of human recombinant tyrosine hydroxylase as determined by proton NMR. Biochemistry. 32: 6381-6390.
- 1993. Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-activated kinase 1 and 2. European Journal of Biochemistry. 217: 715-722.
- 1992. 7-Substituted pterins in humans with suspected pterin-4a-carboinolamine dehydrase deficience. Mechanism of formation via nonenzymatic transformation from 6-substituted pterins. European Journal of Biochemistry. 208: 139-144.
- 1992. Regulation of recombinant human tyrosine hydroxylase isozymes by catecholamine binding and phosphorylation. Structure-activity studies and mechanistic implications. European Journal of Biochemistry. 209: 249-255.
- 1992. Purification and characterization of the blue-green rat pheochromocytoma (PC12) tyrosine hydroxylase with a dopamineFe(III) complex. Reversal of the endogenous feedback inhibition by phosphorylation of serine-40. Biochemical Journal. 284: 687-695.
- 1992. The incorporation of divalent metal ions into recombinant human tyrosine hydroxylase apoenzymes studied by intrinsic fluorescence and 1H-NMR spectroscopy. European Journal of Biochemistry. 210: 23-31.
- 1992. Interaction of phenylalanine hydroxylase by reducing agents in vitro. Biochemical and Biophysical Research Communications - BBRC. 182: 92-98.
- 1992. Characterization of a pancreatic DNase from polyric caeca of Atlantic cod. Fish Physiology & Biochemistry. 9: 439-452.
- 1991. Phosphorylation of human recombinant tyrosine hydroxylase isoforms 1 and 2. An additional phosphorylated residue in TH2 isoform, generated through alternative splicing. Journal of Biological Chemistry. 266: 17124-17130.
- 1991. Recombinant human tyrosine hydroxylase isozymes. Reconstruction with iron and inhibitory effect of other metal ions. European Journal of Biochemistry. 199: 371-378.
- 1991. High-molecular-mass complexes of the regulatory subunits of cyclic AMP-dependent protein kinase. Biochemical Society Transactions. 19: 1163-1165.
- 1991. Supramolecular complexes of cAMP-dependent protein kinase isozymes in bovine adrenal cortex and medulla. Biochemical Society Transactions. 19: 1163-1165.
- 1991. EPR and %1H-NMR spectroscopic studies on the paramagnetic iron at the active site of phenylalanine hydroxylase and its interaction with substrates inhibitors. European Journal of Biochemistry. 198: 675-682.
Reports and theses
- 2011. Disrupted in schizophrenia 1 (DISC1) as a novel candidate gene in attention-deficit/hyperactivity disorder (ADHD) – association with rs1538979 in a Norwegian sample of adult ADHD patients. Universitetet i Bergen.
- 2011. An international multicenter association study of the serotonin transporter gene in persistent ADHD. Universitetet i Bergen.
- 2009. An oxygraphic method for determining kinetic properties and catalytic mechanism of aromatic amino acid hydroxylases. Universitetet i Bergen.
- 1989. Studies on tetrahydropteridine dependent amino acid mono- oxygenases : with special reference to bovine adrenal tyro- sine 3-monooxygenase (tyrosine hydroxylase).
Book sections
- 2012. ADHD og bipolar lidelse. Kapittel 17, pages 367-380. In:
- 2012. Bipolare lidelser. Fagbokforlaget. 487 pages. ISBN: 978-82-450-0585-1.
- 2007. Mechanisms of tyrosine hydroxylase activation by stress activated protein kinases. -, pages 121-126. In:
- 2007. Chemistry and Biology of Pteridines and Folates. 600 pages. ISBN: 978-3-936145-50-2.
- 2002. Binding of 14-3-3 proteins to phosphorylated tyrosine hydroxylase isoforms. Proc. 85-90. In:
- 2002. 12th International Symposium on the Chemistry and Biology of Pteridines and Folates.
- 2002. Role of Phe313/Trp326 in determining substrate specificity in tryptophan and phenylalanine hydroxylases. 97-102. In:
- 2002. Chemistry and Biology of Pteridines and Folates: Proceedings of the 12th International Symposium on Pteridines and Folates, National Institutes of Health, Bethesda, Maryland, June 17-22, 2001. 677 pages. ISBN: 0-7923-7675-7.
- 2002. The conformation of tetrahydrobiopterin free and bound to aromatic amino acid hydroxylases. 67-72. In:
- 2002. Chemistry and Biology of Pteridines and Folates: Proceedings of the 12th International Symposium on Pteridines and Folates, National Institutes of Health, Bethesda, Maryland, June 17-22, 2001. 677 pages. ISBN: 0-7923-7675-7.
- 1997. Photolysis and degradation products of tetrahydropterins. 531-534. In:
- 1997. Chemistry and biology of pteridines and folates: Proceedings of the Eleventh International Symposium on Pteridines and Folates, Berchtesgaden, Germany, June 15-20, 1997. Blackwell Publishing. 894 pages. ISBN: 3-8263-3185-0.
- 1997. Phosphorylation of tyrosine hydroxylase. A comparison of different protein kinases and phosphorylation sites. 509-514. In:
- 1997. Chemistry and biology of pteridines and folates: Proceedings of the Eleventh International Symposium on Pteridines and Folates, Berchtesgaden, Germany, June 15-20, 1997. Blackwell Publishing. 894 pages. ISBN: 3-8263-3185-0.
- 1993. Characterization of the iron environment in recombinant human tyrosine hydroxylase. 71-76. In:
- 1993. Chemistry and Biology of Pteridines and Folates. Proceedings of the Tenth International Symposium on Chemistry and Biology of Pteridines, held March 21 - 26, 1993, in Orange Beach, Alabama. 825 pages. ISBN: 0306445816.
- 1993. Expression of recombinant wild type and mutant forms of human phenylalanine hydroxylase in E. coli. In:
- 1993. Chemistry and Biology of Pteridines and Folates. Proceedings of the Tenth International Symposium on Chemistry and Biology of Pteridines, held March 21 - 26, 1993, in Orange Beach, Alabama. 825 pages. ISBN: 0306445816.
- 1993. Expression of wild type and mutant forms of human phenylalanine hydroxylase in E.Coli. 50-62. In:
- 1993. Adv Exp Med Biol.
- 1993. Interaction of substrate and pterin cofactor with the metal of human tyrosine hydroxylase as determined by %1H-NMR. 77-80. In:
- 1993. Chemistry and Biology of Pteridines and Folates. Proceedings of the Tenth International Symposium on Chemistry and Biology of Pteridines, held March 21 - 26, 1993, in Orange Beach, Alabama. 825 pages. ISBN: 0306445816.
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