Lars A. Akslen | University of Bergen

Lars A.

Akslen

Professor

Department of Clinical Medicine

Visit Address:

Haukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst

5021 Bergen

Postal Address:

Postboks 7804

5021 Bergen

Phone:

+47 55 97 31 82

E-mail:

Lars.Akslen@k1.uib.no

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Publications

Journal articles

Barrett, Jennifer H.; Taylor, John C.; Bright, C; Harland, Mark; Dunning, Alison M; Akslen, Lars A.; Andresen, Per Arne; Avril, Marie-Francoise; Azizi, Esther; Scarra, Giovanna Bianchi; Brossard, Myriam; Brown, Kevin M.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Ghiorzo, Paola; Gillanders, Elizabeth M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Ingvar, Christian; Landi, Maria Teresa; Lang, Julie L.; Lathrop, G. Mark; Lubinski, Jan; Mackie, Rona M.; Molven, Anders; Novakovic, Srdjan; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; van der Stoep, Nienke; van Doorn, Remco; van Workum, Wilberg; Goldstein, Alisa M.; Kanetsky, Peter A.; Pharoah, Paul D.P.; Demenais, Florence; Hayward, Nicholas K.; Bishop, Julia A. Newton; Bishop, D. Timothy; Iles, Mark M. 2014. Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions. International Journal of Cancer. doi: 10.1002/ijc.29099
Haldorsen, Ingfrid S.; Stefansson, Ingunn; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Trovik, Jone; Taxt, Torfinn; Akslen, Lars A.; Salvesen, Helga Birgitte. 2014. Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas. British Journal of Cancer. 110: 107-114. doi: 10.1038/bjc.2013.694
Hellesøy, Monica; Blois, Anna; Tiron, Crina Elena; Mannelqvist, Monica; Akslen, Lars A.; Lorens, James. 2014. Akt1 Activity Regulates Vessel Maturation in a Tissue Engineering Model of Angiogenesis. Tissue Engineering. Part A.
Iles, Mark M.; Bishop, D. Timothy; Taylor, John C.; Hayward, Nicholas K.; Brossard, Myriam; Cust, Anne E.; Dunning, Alison M.; Lee, Jeffrey E.; Moses, Eric K.; Akslen, Lars A.; Investigators, AMFS; Andresen, Per A.; Avril, Marie-Francoise; Azizi, Esther; Scarra, Giovanna Bianchi; Brown, Kevin M.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Harland, Mark; Helsing, Per; Hočevar, Marko; Höiom, Veronica; investigators, IBD; Ingvar, Christian; Kanetsky, Peter A.; Landi, Maria Teresa; Lang, Julie L.; Lathrop, G. Mark; Lubinski, Jan; Mackie, Rona M.; Martin, Nicholas G.; Molven, Anders; Montgomery, Grant W.; Novakovic, Srdian; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; Investigators, QMEGA & QTWIN; Radford-Smith, Graham L.; Randerson-Moor, Juliette; Study Group, SDH; van der Stoep, Nienke; van Doorn, Remco; Whiteman, David C.; MacGregor, Stuart; Pooley, Karen A.; Ward, Sarah V.; Mann, Graham J.; Amos, Christopher I.; Pharoah, Paul D.P.; Demenais, Florence; Law, Matthew H.; Bishop, Julia A. Newton; Barrett, Jennifer H. 2014. The effect on melanoma risk of genes previously associated with telomere length. Journal of the National Cancer Institute. 106.
Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2014. Nestin expression is associated with aggressive cutaneous melanoma of the nodular type. Modern Pathology. 27: 396-401. doi: 10.1038/modpathol.2013.151
Lia, Wenliang; Ai, Nanping; Wang, Suming; Bhattacharya, Nandita; Vrbanac, Vladimir; Collins, Michael; Signoretti, Sabina; Hu, Yanhui; Boyce, Frederick M.; Gravdal, Karsten; Halvorsen, Ole Johan; Nalwoga, Hawa; Akslen, Lars A.; Harlow, Ed; Watnick, Randolph S. 2014. GRK3 is essential for metastatic cells and promotes prostate tumor progression. Proceedings of the National Academy of Science of the United States of America. 111: 1521-1526. doi: 10.1073/pnas.1320638111
Mackay, Helen; Eisenhauer, Elizabeth A.; Kamel-Reid, Suzanne; Tsao, Ming-Sound; Clarke, Blaise; Karakasis, Katherine; Werner, Henrica Maria Johanna; Trovik, Jone; Akslen, Lars A.; Salvesen, Helga Birgitte; Dongsheng, Tu; Oza, Amit M. 2014. Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer. Cancer. 120: 603-610. doi: 10.1002/cncr.28414
Mannelqvist, Monica; Wik, Elisabeth; Stefansson, Ingunn; Akslen, Lars A. 2014. An 18-Gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer. PLoS ONE. 9. doi: 10.1371/journal.pone.0098787
Nygård, Yngve; Haukaas, Svein Andreas; Eide, Geir Egil; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2014. Prostate cancer antigen-3 (PCA3) and PCA3-based nomograms in the diagnosis of prostate cancer: an external validation of Hansen's nomogram on a Norwegian cohort. Scandinavian journal of urology. doi: 10.3109/21681805.2014.949841
Nygård, Yngve; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2014. A positive real-time elastography is an independent marker for detection of high-risk prostate cancers in the primary biopsy setting. BJU International. 113: E90-E97. doi: 10.1111/bju.12401
Ojesina, Akinyemi; Lichtenstein, Lee; Freeman, Samuel S.; Pedamallu, Chandra Sekhar; Imaz-Rosshandler, I; Pugh, Trevor J.; Cherniack, Andrew D.; Ambrogio, Lauren; Cibulskis, Kristian; Bertelsen, Bjørn; Romero-Cordoba, S; Treviño, Victor; Vazquez-Santillan, K; Guadarrama, Alberto Salido; Wright, Alexi A.; Rosenberg, Mara W.; Duke, Fujiko; Kaplan, Bethany; Wang, Rui; Nickerson, Elizabeth; Walline, Heather M; Lawrence, Michael S.; Stewart, Chip; Carter, Scott L.; McKenna, Aaron; Rodriguez-Sanchez, Iram P.; Espinosa-Castilla, Magali; Woie, Kathrine; Bjørge, Line; Wik, Elisabeth; Halle, Mari Kyllesø; Høivik, Erling Andre; Krakstad, Camilla; Gabiño, Nayeli Belem; Gómez-Macías, Gabriela; Valdez-Chapa, Lezmes D.; Garza-Rodríguez, Maria Lourdes; Maytorena, German; Vazquez, Jorge; Rodea, Carlos; Cravioto, Adrian; Cortes, Maria L.; Greulich, Heidi; Crum, Christopher P.; Neuberg, Donna S.; Hidalgo-Miranda, Alfredo; Escareno, Claudia Rangel; Akslen, Lars A.; Carey, Thomas E.; Vintermyr, Olav Karsten; Gabriel, Stacey B.; Barrera-Saldana, Hugo A.; Melendez-Zajgla, Jorge; Getz, Gad; Salvesen, Helga Birgitte; Meyerson, Matthew. 2014. Landscape of genomic alterations in cervical carcinomas. Nature. 506: 371-375. doi: 10.1038/nature12881
Puntervoll, Hanne Eknes; Molven, Anders; Akslen, Lars A. 2014. Frequency of somatic BRAF mutations in melanocytic lesions from patients in a CDK4 melanoma family. Pigment Cell & Melanoma Research. 27: 149-151. doi: 10.1111/pcmr.12191
Reisæter, Lars Anders Rokne; Fütterer, Jurgen; Halvorsen, Ole Johan; Nygård, Yngve; Biermann, Martin; Andersen, Erling; Gravdal, Karsten; Haukaas, Svein Andreas; Monssen, Jan Anker; Huisman, Henkjan J; Akslen, Lars A.; Beisland, Christian; Rørvik, Jarle. 2014. 1.5-T multiparametric MRI using PI-RADS: a region by region analysis to localize the index-tumor of prostate cancer in patients undergoing prostatectomy. Acta Radiologica. doi: 10.1177/0284185114531754
Rogers, Michael S.; Novak, Katherine; Zurakowski, David; Cryan, Lorna M.; Blois, Anna; Lifshits, Eugene; Bø, Trond; Øyan, Anne Margrete; Bender, Elise R.; Lampa, Michael; Kang, Soo-Young; Naxerova, Kamila; Kalland, Karl-Henning; Straume, Oddbjørn; Akslen, Lars A.; Watnick, Randolph S.; Folkman, Judah; Naumov, George N. 2014. Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Molecular Cancer Research. 12: 754-764. doi: 10.1158/1541-7786.MCR-13-0532-T
Shahrabi-Farahani, Shokoufeh; Wang, Lili; Zwaans, Bernadette MM; Santana, Jeans M; Shimizu, Akio; Takashima, Seiji; Kreuter, Michael; Coultas, Leigh; D'Amore, Patricia A; Arbeit, Jeffrey M.; Akslen, Lars A.; Bielenberg, Diane R. 2014. Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas. Laboratory Investigation. 94: 752-765. doi: 10.1038/labinvest.2014.66
Tangen, Ingvild Løberg; Krakstad, Camilla; Halle, Mari Kyllesø; Werner, Henrica Maria Johanna; Øyan, Anne Margrete; Kusonmano, Kanthida; Petersen, Kjell; Kalland, Karl-Henning; Akslen, Lars A.; Trovik, Jone; Rodriguez, Antoni Hurtado; Salvesen, Helga Birgitte. 2014. Switch in FOXA1 status associates with endometrial cancer progression. PLoS ONE. 9. doi: 10.1371/journal.pone.0098069
Werner, Henrica Maria Johanna; Trovik, Jone; Halle, Mari Kyllesø; Wik, Elisabeth; Akslen, Lars A.; Birkeland, Even; Bredholt, Therese; Tangen, Ingvild Løberg; Krakstad, Camilla; Salvesen, Helga Birgitte. 2014. Stathmin Protein Level, a Potential Peredictive Marker for Taxane Treatment Response in Endometrial Cancer. PLoS ONE. 9. doi: 10.1371/journal.pone.0090141
Wik, Elisabeth; Trovik, Jone; Kusonmano, Kanthida; Birkeland, Even; Raeder, MB; Pashtan, I; Hoivik, EA; Krakstad, Camilla; Werner, HM; Holst, Frederik; Mjøs, Siv; Halle, MK; Mannelqvist, Monica; Mauland, Karen Klepsland; Oyan, Anne M; Stefansson, Ingunn; Petersen, K; Simon, R; Sherniack, A; Meyerson, M; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2014. Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and P13K alterations. Gynecologic Oncology. 134: 599-606.

Arnesen, Thomas; Glomnes, Nina; Strømsøy, Siri S.; Knappskog, Stian; Heie, Anette; Akslen, Lars A.; Grytaas, Marianne Aardal; Varhaug, Jan Erik; Gimm, Oliver; Brauckhoff, Michael. 2013. Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway. Langenbeck's archives of surgery (Print). 398: 869-874. doi: 10.1007/s00423-013-1093-2
Catena, Raúl; Bhattacharya, Nandita; El Rayes, Tina; Wang, Suming; Choi, Hyejin; Gao, Dingcheng; Ryu, Seongho; Joshi, Natasha; Bielenberg, Diane; Lee, Sharrell B.; Haukaas, Svein Andreas; Gravdal, Karsten; Halvorsen, Ole Johan; Akslen, Lars A.; Watnick, Randolph S.; Mittal, Vivek. 2013. Bone marrow-derived Gr1(+) cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1. Cancer Discovery. 3: 578-589. doi: 10.1158/2159-8290.CD-12-0476
Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. 2013. Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients. Breast Cancer Research and Treatment. 140: 463-473. doi: 10.1007/s10549-013-2647-2
Garcia-Dios, Diego A; Lambrechts, Diether; Coenegrachts, Lieve; Vandenput, Ingrid; Capoen, An; Webb, Penelope M.; Ferguson, Kaltin; Akslen, Lars A.; Claes, Bart; Vergote, Ignace; Moerman, Philippe; Robays, Johan Van; Marcickiewicz, Janusz; Salvesen, Helga Birgitte; Spurdle, Amanda B; Amant, Frédéric. 2013. High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma. Gynecologic Oncology. 128: 327-334. doi: 10.1016/j.ygyno.2012.11.037
Geisler, Jürgen; Bachmann, Ingeborg M.; Nyakas, Marta Sølvi; Helsing, Per; Fjøsne, Hans E.; Mæhle, Lovise Olaug; Aamdal, Steinar; Eide, Nils; Svendsen, Henrik Løvendahl; Straume, Oddbjørn; Robsahm, Trude Eid; Dolven-Jacobsen, Kari; Akslen, Lars A. 2013. Malignt melanom – diagnostikk, behandling og oppfølging i Norge. Tidsskrift for Den norske legeforening. 133: 2154-2159. doi: 10.4045/tidsskr.12.1416
Haldorsen, Ingfrid S.; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Stefansson, Ingunn Marie; Akslen, Lars A.; Trovik, Jone; Taxt, Torfinn; Salvesen, Helga Birgitte. 2013. Dynamic contrast-enhanced MRI in endometrial carcinoma identifies patients at increased risk of recurrence. European Radiology. 23: 2916-2925. doi: 10.1007/s00330-013-2901-3
Hoem, Dag; Straume, Oddbjørn; Immervoll, Heike; Akslen, Lars A.; Molven, Anders. 2013. Vascular proliferation is associated with survival in pancreatic ductal adenocarcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 121: 1037-1046. doi: 10.1111/apm.12057
Iles, Mark M.; Law, Matthew H.; Stacey, Simon N.; Han, Jiali; Fang, Shenying; Pfeiffer, Ruth; Harland, Mark; MacGregor, Stuart; Taylor, John C.; Aben, Katja K.; Akslen, Lars A.; Avril, Marie Françoise; Azizi, Esther; Bakker, Bert; Benediktsdottir, Kristun R.; Bergman, Wilma; Scarra, Giovanna Bianchi; Brown, Kevin M.; Calista, Donato; Chaudru, Valerie; Fargnoli, Marie Concetta; Cust, Anne E.; Demenais, Florence; de Waal, Anne C.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Galan, Pilar; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Hopper, John L.; Ingvar, Christian; Janssen, Marjolein; Jenkins, Mark A.; Kanetsky, Peter A.; Kiemeney, Lambertus A.; Lang, Julie L.; Lathrop, G. Mark; Leachman, Sancy; Lee, Jeffrey E.; Lubiński, Jan; Mackie, Rona M.; Mann, Graham J.; Martin, Nicholas G.; Mayordomo, Jose Ignacio; Molven, Anders; Mulder, Suzanne; Nagore, Eduardo; Novakovic, Srdjan; Okamoto, Ichiro; Olafsson, Jon H.; Olsson, Håkan; Pehamberger, Hubert; Peris, Ketty; Grasa, Maria Pilar; Planelles, Dolores; Puig, Susana; Puig-Butille, Joan Anton; Randerson-Moor, Juliette; Requena, Celia; Rivoltini, Licia; Rodolfo, Monica; Santinami, Mario; Sigurgeirsson, Bardur; Snowden, Helen; Song, Fengju; Sulem, Patrick; Thorisdottir, Kristin; Tuominen, Rainer; Van Belle, Patricia; van der Stoep, Nienke; van Rossum, Michelle M.; Wei, Qingyi; Wendt, Judith; Zelenika, Diane; Zhang, Mingfeng; Landi, Maria Teresa; Thorleifsson, Gudmar; Bishop, D. Timothy; Amos, Christopher I.; Hayward, Nicholas K.; Stefansson, Kari; Bishop, Julia A. Newton; Barrett, Jennifer H. 2013. A variant in FTO shows association with melanoma risk not due to BMI. Nature Genetics. 45: 428-432. doi: 10.1038/ng.2571
Klingen, Tor Audun; Chen, Ying; Suhrke, Pål; Stefansson, Ingunn Marie; Gundersen, Marian D.; Akslen, Lars A. 2013. Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas. Diagnostic Pathology. 8. doi: 10.1186/1746-1596-8-80
Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2013. Proliferation markers PHH3, Ki67 and Mimtotic count all show significant associations with features of aggressive breast carcinomas and reduced survival. Laboratory Investigation. 93: 50A-50A.
Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2013. Proliferation markers PHH3, Ki67 and mitotic count all show significant associations with features of aggressive breast carcinomas and reduced survival. Modern Pathology. 26: 50A-50A.
Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Bofin, Anna M.; Engebråten, Olav; Mælandsmo, Gunhild; Akslen, Lars A.; Gribbestad, Ingrid S. 2013. Low-molecular contrast agent DCE-MRI and DW-MRI in early assessment of bevacizumab treatment in breast cancer xenografts. Journal of Magnetic Resonance Imaging. 38: 1043-1053. Published 2013-01-17. doi: 10.1002/jmri.24079
Ozhand, Ali; Lee, Eunjung; Wu, Anna H.; Ellingjord-Dale, Merete; Akslen, Lars A.; McKean-Cowdin, Roberta; Ursin, Giske. 2013. Variation in inflammatory cytokine/growth-factor genes and mammographic density in premenopausal women aged 50-55. PLoS ONE. 8. 8 pages. doi: 10.1371/journal.pone.0065313
Pedersen, Torbjørn Østvik; Blois, Anna; Xing, Zhe; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Akslen, Lars A.; Lorens, James; Leknes, Knut N.; Fristad, Inge; Mustafa, Kamal Babikeir Eln. 2013. Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs. Stem Cell Research & Therapy. 4. 10 pages. doi: 10.1186/scrt202
Puntervoll, Hanne Eknes; Yang, Xiaohong R.; Vetti, Hildegunn Høberg; Bachmann, Ingeborg M.; Avril, Marie Françoise; Benfodda, Meriem; Catricala, Caterina; Dalle, Stéphane; Duval-Modeste, Anne B.; Ghiorzo, Paola; Grammatico, Paola; Harland, Mark; Hayward, Nicholas K.; Hu, Hui-Han; Jouary, Thomas; Martin-Denavit, Tanguy; Ozola, Aija; Palmer, Jane M.; Pastorino, Lorenza; Pjanova, Dace; Soufir, Nadem; Steine, Solrun; Stratigos, Alexander J.; Thomas, Luc; Tinat, Julie; Tsao, Hensin; Veinalde, Rūta; Tucker, Margaret A.; Bressac-de Paillerets, Brigitte B.D.; Newton-Bishop, Julia A.; Goldstein, Alisa M.; Akslen, Lars A.; Molven, Anders. 2013. Melanoma prone families with CDK4 germline mutation: phenotypic profile and associations with MC1R variants. Journal of Medical Genetics. 50: 264-U82. doi: 10.1136/jmedgenet-2012-101455
Ræder, Maria B; Birkeland, Even; Trovik, Jone; Krakstad, Camilla; Shehata, Shyemaa; Schumacher, Steven; Zack, Travis I.; Krohn, Antje; Werner, Henrica Maria Johanna; Moody, Susan E.; Wik, Elisabeth; Stefansson, Ingunn Marie; Holst, Frederik; Øyan, Anne Margrete; Tamayo, Pablo; Mesirov, Jill P.; Kalland, Karl-Henning; Akslen, Lars A.; Simon, Ronald; Beroukhim, Rameen; Salvesen, Helga Birgitte. 2013. Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers. PLoS ONE. 8. 9 pages. doi: 10.1371/journal.pone.0054873
Tangen, Ingvild Løberg; Krakstad, Camilla; Werner, Henrica Maria Johanna; Øyan, Anne Margrete; Kusonmano, Kanthida; Gilfillan, Siv; Kalland, Karl-Henning; Akslen, Lars A.; Trovik, Jone; Hurtado, A; Salvesen, Helga Birgitte. 2013. FOXA1 LOSS IN ENDOMETRIAL CANCER IS ASSOCIATED WITH POOR PROGNOSIS AND ER ALPHA LOSS. International Journal of Gynecological Cancer. 23. 1 pages.
Trovik, Jone; Wik, Elisabeth; Werner, Henrica Maria Johanna; Krakstad, Camilla; Helland, Harald; Vandenput, Ingrid; Njølstad, Tormund Salvesen; Stefansson, Ingunn; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial. European Journal of Cancer. 49: 3431-3441. doi: 10.1016/j.ejca.2013.06.016
Veinalde, Rūta; Ozola, Aija; Azarjana, Kristine; Molven, Anders; Akslen, Lars A.; Donina, Simona; Proboka, Guna; Cema, Ingrida; Baginskis, Ainars; Pjanova, Dace. 2013. Analysis of Latvian familial melanoma patients shows novel variants in the noncoding regions of CDKN2A and that the CDK4 mutation R24H is a founder mutation. Melanoma research. 23: 221-226. doi: 10.1097/CMR.0b013e3283608695
Werner, Henrica Maria Johanna; Berg, Anna; Wik, Elisabeth; Birkeland, Even; Krakstad, Camilla; Kusonmano, Kanthida; Petersen, Kjell; Kalland, Karl-Henning; Øyan, Anne Margrete; Akslen, Lars A.; Trovik, Jone; Salvesen, Helga Birgitte. 2013. ARID1A loss is prevalent in endometrial hyperplasia with atypia and low-grade endometrioid carcinomas. Modern Pathology. 26: 428-434. doi: 10.1038/modpathol.2012.174
Wik, Elisabeth; Birkeland, Even; Trovik, Jone; Werner, Henrica Maria Johanna; Høivik, Erling Andre; Mjøs, Siv; Krakstad, Camilla; Kusonmano, Kanthida; Mauland, Karen Klepsland; Stefansson, Ingunn Marie; Holst, Frederik; Petersen, Kjell; Øyan, Anne Margrete; Simon, Roland; Kalland, Karl-Henning; Ricketts, William; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. High phospho-stathmin(Serine38) expression identifies aggressive endometrial cancer and suggests an association with PI3K inhibition. Clinical Cancer Research. 19: 2331-2341. doi: 10.1158/1078-0432.CCR-12-3413
Wik, Elisabeth; Ræder, Maria B; Krakstad, Camilla; Trovik, Jone; Birkeland, Even; Høivik, Erling Andre; Mjøs, Siv; Werner, Henrica Maria Johanna; Mannelqvist, Monica; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. Lack of estrogen receptor-alpha is associated with epithelial-mesenchymal transition and PI3K alterations in endometrial carcinoma. Clinical Cancer Research. 19: 1094-1105. doi: 10.1158/1078-0432.CCR-12-3039

Arnes, Jarle; Stefansson, Ingunn Marie; Straume, Oddbjørn; Baak, Jan P.A.; Lønning, Per Eystein; Foulkes, William D.; Akslen, Lars A. 2012. Vascular proliferation is a prognostic factor in breast cancer. Breast Cancer Research and Treatment. 133: 501-510. doi: 10.1007/s10549-011-1785-7
Birkeland, Even; Wik, Elisabeth; Mjøs, Siv; Høivik, Erling Andre; Trovik, Jone; Werner, Henrica Maria Johanna; Kusonmano, Kanthida; Petersen, Kjell; Ræder, Maria B; Holst, Frederik; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Simon, R; Krakstad, Camilla; Salvesen, Helga Birgitte. 2012. KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer. British Journal of Cancer. 107: 1997-2004. doi: 10.1038/bjc.2012.477
Brauckhoff, Michael; Varhaug, Jan Erik; Hauptmann, Steffen; Akslen, Lars A.; Thanh, P. Nguyen; Viste, Asgaut; Heie, Anette; Dralle, Henning. 2012. Peritoneal carcinosis in apparently benign cortisol producing adrenal adenoma >= 5 cm in diameter: the need of regular postoperative surveillance. Experimental and clinical endocrinology & diabetes. 120: 472-476. doi: 10.1055/s-0032-1321807
Ellingjord-Dale, Merete; Lee, Eunjung; Couto, Elisabeth; Ozhand, Ali; Qureshi, Samera Azeem; Hofvind, Solveig; Van Den Berg, David J; Akslen, Lars A.; Grotmol, Tom; Ursin, Giske. 2012. Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users. Breast Cancer Research. 14. doi: 10.1186/bcr3337
Helsing, Per; Nymoen, Dag Andre; Rootwelt, Helge; Vårdal, Mari H; Akslen, Lars A.; Molven, Anders; Andresen, Per Arne. 2012. MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas. Genes, Chromosomes and Cancer. 51: 654-661. doi: 10.1002/gcc.21952
Huuse, Else Marie; Moestue, Siver Andreas; Lindholm, Evita Maria; Bathen, Tone Frost; Nalwoga, Hawa; Krüger, Kristi; Bofin, Anna M.; Mælandsmo, Gunhild; Akslen, Lars A.; Engebråten, Olav; Gribbestad, Ingrid S. 2012. In vivo MRI and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts. Journal of Magnetic Resonance Imaging. 35: 1098-1107. doi: 10.1002/jmri.23507
Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2012. Prognostic impact of proliferation markers Ki-67, PHH3 and mitotic count in breast carcinomas. Virchows Archiv. 461: S5-S5.
Krakstad, Camilla; Trovik, Jone; Wik, Elisabeth; Engelsen, Ingeborg Bøe; Werner, Henrica Maria Johanna; Birkeland, Even; Ræder, Maria B; Øyan, Anne Margrete; Stefansson, Ingunn Marie; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2012. Loss of GPER identifies new targets for therapy among a subgroup of ER alpha-positive endometrial cancer patients with poor outcome. British Journal of Cancer. 106: 1682-1688. doi: 10.1038/bjc.2012.91
Krüger, Kristi; Stefansson, Ingunn Marie; Collett, Karin; Arnes, Jarle; Aas, Turid; Akslen, Lars A. 2012. Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer. Breast. 1-7. doi: 10.1016/j.breast.2012.07.008
Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2012. Prognostic Importance of the Mitotic Marker Phosphohistone H3 in Cutaneous Nodular Melanoma. Journal of Investigative Dermatology. 132: 1247-1252. doi: 10.1038/jid.2011.464
Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2012. Tumor necrosis is a prognostic factor in thick cutaneous melanoma. American Journal of Surgical Pathology. 36: 1477-1482. doi: 10.1097/PAS.0b013e31825a5b45
Lindholm, Evita Maria; Kristian, Alexandr; Nalwoga, Hawa; Kruger, Kristi; Nygård, Ståle; Akslen, Lars A.; Mælandsmo, Gunhild; Engebråten, Olav. 2012. Effect of antiangiogenic therapy on tumor growth, vasculature and kinase activity in basal- and luminal-like breast cancer xenografts. Molecular Oncology. 6: 418-427. doi: 10.1016/j.molonc.2012.03.006
Mannelqvist, Monica; Stefansson, Ingunn Marie; Wik, Elisabeth; Kusonmano, Kanthida; Ræder, Maria B; Øyan, Anne Margrete; Kalland, Karl-Henning; Moses, Marsha A.; Salvesen, Helga Birgitte; Akslen, Lars A. 2012. Lipocalin 2 expression is associated with aggressive features of endometrial cancer. BMC Cancer. 12. 7 pages. doi: 10.1186/1471-2407-12-169
Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian; Kalland, Karl-Henning; Chekenya, Martha; Akslen, Lars A.; Sleire, Linda; Enger, Per Øyvind; Reed, Rolf K.; Øyan, Anne Margrete; Stuhr, Linda Elin Birkhaug. 2012. Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. BMC Cancer. 12. 10 pages. doi: 10.1186/1471-2407-12-21
Moestue, Siver Andreas; Flatabø, Silje; Huuse, Else Marie; Lindholm, Evita Maria; Engebraaten, Olav; Maelandsmo, Gunnhild M; Akslen, Lars A.; Gribbestad, Ingrid S. 2012. Metabolic Responses to VEGF Inhibition in Patient-derived Breast Cancer Xenografts. European Journal of Cancer. 48: S32-S32.
Nalwoga, Hawa; Arnes, Jarle; Wabinga, H; Akslen, Lars A. 2012. Expression of hypoxia-inducible factor-1a and associations with vascular endothelial growth factor expression, high microvessel density and features of aggressive tumors in African breast cancer. Virchows Archiv. 461: S249-S249.
Nygård, Yngve; Haukaas, Svein Andreas; Waage, Jo Erling Riise; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2012. Combination of real-time elastography and urine prostate cancer gene 3 (PCA3) detects more than 97 % of significant prostate cancers. Scandinavian Journal of Urology and Nephrology. 47: 211-216. doi: 10.3109/00365599.2012.727859
Schuster, Cornelia; Eikesdal, Hans Petter; Puntervoll, Hanne Eknes; Geisler, Jürgen; Geisler, Stephanie; Heinrich, Daniel; Molven, Anders; Lønning, Per Eystein; Akslen, Lars A.; Straume, Oddbjørn. 2012. Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension. PLoS ONE. 7. 8 pages. doi: 10.1371/journal.pone.0038364
Straume, Oddbjørn; Shimamura, Takeshi; Lampa, Michael J.G.; Carretero, Julian; Øyan, Anne Margrete; Jia, Di; Borgman, Christa L.; Soucheray, Margaret; Downing, Sean R.; Short, Sarah M.; Kang, Soo-Young; Wang, Suoming; Chen, Liang; Collett, Karin; Bachmann, Ingeborg M.; Wong, Kwok-Kin; Shapiro, Geoffrey I.; Kalland, Karl-Henning; Folkman, Judah; Watnick, Randolph S.; Akslen, Lars A.; Naumov, George N. 2012. Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer. Proceedings of the National Academy of Science of the United States of America. 109: 8699-8704. doi: 10.1073/pnas.1017909109
Wik, Elisabeth; Rader, Maria; Krakstad, Camilla; Trovik, Jone; Erling, Hoivik; Mjøs, Siv; Stefansson, Ingunn Marie; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga. 2012. Estrogen receptor a loss in endometrial carcinoma is associated with epithelial-to-mesenchymal transition and a potential for PI3Kinase inhibition. Virchows Archiv. 461: S18-S18.

Akslen, Lars A.; Straume, Oddbjørn; Geisler, Stephanie; Sørlie, Therese; Chi, Jen-Tan Ashley; Aas, Turid; Børresen-Dale, Anne-Lise; Lønning, Per Eystein. 2011. Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer. British Journal of Cancer. 105: 9-12. doi: 10.1038/bjc.2011.203
Barrett, Jennifer H.; Iles, MM; Harland, M; Taylor, JC; Aitken, JF; Andresen, Per Arne; Akslen, Lars A.; Armstrong, BK; Avril, MF; Azizi, E; Bakker, B; Bergman, W; Bianchi-Scarra, G; Bressac-de Paillerets, B; Calista, D; Cannon-Albright, LA; Corda, E; Cust, AE; Debniak, T; Duffy, D; Dunning, AM; Easton, DF; Friedman, E; Galan, P; Ghiorzo, P; Giles, GG; Hansson, J; Hocevar, M; Hoiom, V; Hopper, JL; Ingvar, C; Janssen, B; Jenkins, MA; Jonsson, G; Kefford, RF; Landi, G; Landi, MT; Lang, J; Lubinski, J; Mackie, R; Malvehy, J; Martin, NG; Molven, Anders; Montgomery, GW; van Nieuwpoort, FA; Novakovic, S; Olsson, H; Pastorino, L; Puig, S; Puig-Butille, JA; Randerson-Moor, J; Snowden, H; Tuominen, R; VanBelle, P; van der Stoep, N; Whiteman, DC; Zelenika, D; Han, JL; Fang, SY; Lee, JE; Wei, QY; Lathrop, GM; Gillanders, EM; Brown, KM; Goldstein, AM; Kanetsky, PA; Mann, GJ; MacGregor, S; Elder, DE; Amos, CI; Hayward, NK; Gruis, NA; Demenais, F; Bishop, JAN; Bishop, D. Timothy. 2011. Genome-wide association study identifies three new melanoma susceptibility loci. Nature Genetics. 43: 1108-U98. doi: 10.1038/ng.959
Hegen, Anja; Blois, Anna; Tiron, Crina Elena; Hellesøy, Monica; Micklem, David Robert; Nör, Jacques E; Akslen, Lars A.; Lorens, James. 2011. Efficient in vivo vascularization of tissue-engineering scaffolds. Journal of Tissue Engineering and Regenerative Medicine. 5: E52-E62. doi: 10.1002/term.336
Ke, Xisong; Li, Wencheng; Hovland, Randi; Qu, Yi; Liu, Run-hui; McCormack, Emmet Martin; Thorsen, Frits Alan; Olsen, Jan Roger; Molven, Anders; Kogan-Sakin, Ira; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2011. Reprogramming of cell junction modules during stepwise epithelial to mesenchymal transition and accumulation of malignant features in vitro in a prostate cell model. Experimental Cell Research. 317: 234-247. doi: 10.1016/j.yexcr.2010.10.009
Mannelqvist, Monica; Stefansson, Ingunn Marie; Bredholt, Geir; Bø, Trond Hellem; Øyan, Anne Margrete; Jonassen, Inge; Kalland, Karl-Henning; Salvesen, Helga Birgitte; Akslen, Lars A. 2011. Gene Expression Patterns Related to Vascular Invasion and Aggressive Features in Endometrial Cancer. American Journal of Pathology. 178: 861-871. doi: 10.1016/j.ajpath.2010.10.040
Mauland, Karen Klepsland; Trovik, Jone; Wik, Elisabeth; Ræder, Maria B; Njølstad, Tormund Salvesen; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Bjørge, Tone; Akslen, Lars A.; Salvesen, Helga Birgitte. 2011. High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer. British Journal of Cancer. 104: 921-926. doi: 10.1038/bjc.2011.46
Myklebust, Line Merethe; Akslen, Lars A.; Varhaug, Jan Erik; Lillehaug, Johan R. 2011. Receptor for Activated Protein C Kinase 1 (RACK1) Is Overexpressed in Papillary Thyroid Carcinoma. Thyroid. 21: 1217-1225. doi: 10.1089/thy.2010.0186
Nalwoga, Hawa; Arnes, Jarle; Stefansson, Ingunn Marie; Wabinga, Henry; Foulkes, William D.; Akslen, Lars A. 2011. Vascular proliferation is increased in basal-like breast cancer. Breast Cancer Research and Treatment. 130: 1063-1071. doi: 10.1007/s10549-011-1740-7
Tiron, Crina Elena; Gjerdrum, Christine; Høiby, Torill; Maugen, Hallvard; Stefansson, Ingunn Marie; Sandal, Tone; Collett, Karin; Li, Shan; McCormack, Emmet Martin; Gjertsen, Bjørn Tore; Micklem, David Robert; Akslen, Lars A.; Glackin, Carlotta A.; Lorens, James. 2011. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Clinical and Experimental Metastasis. 28: 234-235.
Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Njølstad, Tormund Salvesen; Vandenput, Ingrid; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte; Ellstrøm Engh, Marie; Oddenes, Klaus; Rokne, Jan Anders; Tjugum, Jostein; Lode, Margaret Sævik. 2011. Stathmin Overexpression Identifies High-Risk Patients and Lymph Node Metastasis in Endometrial Cancer. Clinical Cancer Research. 17: 3368-3377. doi: 10.1158/1078-0432.CCR-10-2412
Vandenput, Ingrid; Trovik, Jone; Leunen, Karin; Wik, Elisabeth; Stefansson, Ingunn Marie; Akslen, Lars A.; Moerman, Philippe; Vergote, Ignace; Salvesen, Helga Birgitte; Amant, Frédéric. 2011. Evolution in endometrial cancer evidence from an immunohistochemical study. International Journal of Gynecological Cancer. 21: 316-322. doi: 10.1097/IGC.0b013e31820575f5

Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2010. Multimodal imaging of differentiated thyroid cancer: FDG-PET-CT, I-131-SPECT-CT and ultrasound. European Journal of Nuclear Medicine and Molecular Imaging. 37: S291-S291.
Blows, Fiona M.; Driver, Kristy E.; Schmidt, Marjanka K.; Broeks, Annegien; van Leeuwen, Fllora E.; Wesseling, Jelle; Cheang, Maggie C.U.; Gelmon, Karen; Nielsen, Torsten O.; Blomqvist, Carl; Heikkila, Päivi; Heikkinen, Tuomas; Nevanlinna, Heli; Akslen, Lars A.; Bégin, Louis R.; Foulkes, William D.; Couch, Fergus J.; Wang, Xianshu; Cafourek, Vicky; Olson, Janet E.; Baglietto, Laura; Giles, Graham G.; Severi, Gianluca; McLean, Catriona A.; Southey, Melissa C.; Rakha, Emad A.; Green, Andrew R.; Ellis, Ian O.; Sherman, Mark E.; Lissowska, Jolanta; Anderson, William F.; Cox, Angela; Cross, Simon S.; Reed, Malcolm W.R.; Provenzano, Elena; Dawson, Sarah-Jane; Dunning, Alison M.; Humphreys, Manjeet; Easton, Douglas F.; García-Closas, Montserrat; Caldas, Carlos; Pharoah, Paul D.; Huntsman, David G. 2010. Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies. PLoS Medicine. 7. 12 pages. doi: 10.1371/journal.pmed.1000279
Gjerdrum, Christine; Tiron, Crina Elena; Høiby, Torill; Stefansson, Ingunn Marie; Haugen, Hallvard; Sandal, Tone; Collett, Karin; Li, Shan; McCormack, Emmet Martin; Gjertsen, Bjørn Tore; Micklem, David Robert; Akslen, Lars A.; Glackin, Carlotta A.; Lorens, James. 2010. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Proceedings of the National Academy of Science of the United States of America. 107: 1124-1129. doi: 10.1073/pnas.0909333107
Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2010. Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma. BMC Cancer. 10. 15 pages. doi: 10.1186/1471-2407-10-140
Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2010. Expression of aldehyde dehydrogenase a (ALDH1) is associated with basal-like markers and features of aggressive tumors in African breast cancer. British Journal of Cancer. 102: 369-375. doi: 10.1038/sj.bjc.6605488
Stefansson, Ingunn Marie; Mannelquist, M; Salvesen, HB; Akslen, Lars A. 2010. Prognostic importance of vascular proliferation and tumor cell invasion in blood and lymphatic vessels in endometrial carcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 118: 248-248.
Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Carter, Scott L.; Beroukhim, Rameen; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2010. Stathmin is superior to AKT and phospho-AKT staining for the detection of phosphoinositide 3-kinase activation and aggressive endometrial cancer. Histopathology. 57: 641-646. doi: 10.1111/j.1365-2559.2010.03661.x

Arnes, Jarle; Begin, LR; Brunet, JS; Nielsen, TO; Foulkes, WD; Akslen, Lars A.; Akslen, LA. 2009. Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer. Journal of Clinical Pathology. 62: 139-146. doi: 10.1136/jcp.2008.056291
Bhriain, Hannah Ni; Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Akslen, Lars A.; Salvesen, Helga Birgitte; Staff, Anne Cathrine. 2009. Plasma calprotectin concentrations in women with endometrial carcinoma. Gynecologic Oncology. 114: 491-495. doi: 10.1016/j.ygyno.2009.06.008
Bruland, Ove; Fluge, Øystein; Akslen, Lars A.; Eiken, Hans Geir; Lillehaug, Johan R.; Varhaug, Jan Erik; Knappskog, Per Morten. 2009. Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas. BMC Cancer. 9: 425. doi: 10.1186/1471-2407-9-425
Engelsen, Ingeborg Bøe; Akslen, Lars A.; Salvesen, Helga Birgitte. 2009. Biologic markers in endometrial cancer treatment. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 693-707. doi: 10.1111/j.1600-0463.2009.02467.x
Etemadmoghadam, Dariush; deFazio, Anna; Beroukhim, Rameen; Mermel, Craig; George, Joshy; Getz, Gad; Tothill, Richard; Okamoto, Aikou; Ræder, Maria Therese Barøy; Harnett, Paul; Lade, Stephen; Akslen, Lars A.; Tinker, Anna V.; Locandro, Bianca; Alsop, Kathryn; Chiew, Yoke-Eng; Traficante, Nadia; Fereday, Sian; Johnson, Daryl; Fox, Stephen; Sellers, William R.; Urashima, Mitsuyoshi; Salvesen, Helga Birgitte; Meyerson, Matthew; Bowtell, David. 2009. Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas. Clinical Cancer Research. 15: 1417-1427. doi: 10.1158/1078-0432.CCR-08-1564
Fluge, Øystein; Gravdal, K; Carlsen, E; Carlsen, Erik; Vonen, Barthold; Kjellevold, K; Refsum, S; Lilleng, R; Eide, Tor J.; Halvorsen, TB; Tveit, KM; Tveit, Kjell Magne; Otte, AP; Akslen, LA; Dahl, O. 2009. Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. British Journal of Cancer. 101: 1282-1289. doi: 10.1038/sj.bjc.6605333
Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2009. Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer. Cancer Research. 69: 4708-4715. doi: 10.1158/0008-5472.CAN-08-4417
Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2009. Proliferation of immature tumor vessels is a novel marker of clinical progress in prostate cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 233-233. doi: 10.1111/j.1600-0463.2009.02434.x
Kang, Soo-Young; Halvorsen, Ole Johan; Gravdal, Karsten; Bhattacharya, Nandita; Lee, Jung Min; Liu, Nathan W.; Johnston, Brian T.; Johnston, Adam B.; Haukaas, Svein Andreas; Aamodt, Kristie; Yoo, Sun; Akslen, Lars A.; Watnick, Randolph S. 2009. Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1. Proceedings of the National Academy of Science of the United States of America. 106: 12115-12120. doi: 10.1073/pnas.0903120106
Ke, Xisong; Qu, Yi; Rostad, Kari; Li, Wen-Cheng; Lin, Biaoyang; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Jonassen, Inge; Petersen, Kjell; Goldfinger, Naomi; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2009. Genome-wide profiling of histone H3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis. PLoS ONE. 4. 14 pages. doi: 10.1371/journal.pone0004687
Klingen, Tor A; Klaasen, Heman; Aas, Hans; Chen, Ying; Akslen, Lars A. 2009. Secondary breast cancer: a 5-year population-based study with review of the literature. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 762-767. doi: 10.1111/j.1600-0463.2009.02529.x
Klingen, Tor Audun; Klaasen, Herman; Chen, Ying; Akslen, Lars A. 2009. Secondary breast cancer: a 5-year population-based study with review of the literature. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 762-767. doi: 10.1111/j.1600-0463.2009.02529.x
Mannelqvist, Monica; Stefansson, Ingunn Marie; Salvesen, Helga Birgitte; Akslen, Lars A. 2009. Importance of tumour cell invasion in blood and lymphatic vasculature among patients with endometrial carcinoma. Histopathology. 54: 174-183. doi: 10.1111/j.1365-2559.2008.03201.x
Moen, Ingrid; Øyan, Anne Margrete; Kalland, Karl-Henning; Tronstad, Karl Johan; Akslen, Lars A.; Chekenya, Martha; Sakariassen, Per Øystein; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2009. Hyperoxic treatment induces mesenchymal to epithelial transition in a rat adenocarcinoma model. PLoS ONE. 4. doi: 10.1371/journal.pone.0006381
Mæhle, BO; Mæhle, Bjørn Ove; Collett, Karin; Tretli, Steinar; Akslen, Lars A.; Grotmol, Tom. 2009. Estrogen receptor β– an independent prognostic marker in estrogen receptor α and progesterone receptor-positive breast cancer? Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 644-650. doi: 10.1111/j.1600-0463.2009.02510.x
Naumov, George N.; Nilsson, Monique B.; Cascone, Tina; Briggs, Alexandra; Straume, Oddbjørn; Akslen, Lars A.; Lifshits, Eugene; Byers, Lauren Averett; Xu, Li; Wu, Hua-kang; Jänne, Pasi; Kobayashi, Susumu; Halmos, Balazs; Tenen, Daniel; Tang, Xi M.; Engelman, Jeffrey; Yeap, Beow; Folkman, Judah; Johnson, Bruce E.; Heymach, John V. 2009. Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance. Clinical Cancer Research. 15: 3484-3494. doi: 10.1158/1078-0432.CCR-08-2904
Pjanova, Dace; Molven, Anders; Akslen, Lars A.; Engele, Ludmila; Streinerte, Baiba; Azarjana, Kristine; Heisele, Olita. 2009. Identification of a CDK4 R24H mutation-positive melanoma family by analysis of early-onset melanoma patients in Latvia. Melanoma research. 19: 119-122. doi: 10.1097/CMR.0b013e3283287d3e
Rakha, Emad A.; Elsheikh, Somaia E.; Aleskandarany, Muhammed A.; Habashi, Hany O.; Green, Andrew R.; Powe, Desmond G.; El-Sayed, Maysa E.; Benhasouna, Ahmed; Brunet, Jean-Sébastien; Akslen, Lars A.; Evans, Andy J.; Blamey, Roger; Reis-Filho, Jorge S.; Foulkes, William D.; Ellis, Ian O. 2009. Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes. Clinical Cancer Research. 15: 2302-2310. doi: 10.1158/1078-0432.CCR-08-2132
Rostad, Kari; Hellwinkel, Olaf JC; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Øyan, Anne Margrete; Haese, Alexander; Budäus, Lars; Albrecht, Heiko; Akslen, Lars A.; Schlomm, Thorsten; Kalland, Karl-Henning. 2009. TMPRSS2:ERG fusion transcripts in urine from prostate cancer patients correlate with a less favorable prognosis. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 117: 575-582. doi: 10.1111/j.1600-0463.2009.02517.x
Salvesen, Helga Birgitte; Carter, Scott L.; Mannelqvist, Monica; Dutt, Amit; Getz, Gad; Stefansson, Ingunn Marie; Ræder, Maria Therese Barøy; Sos, Martin L.; Engelsen, Ingeborg Bøe; Trovik, Jone; Wik, Elisabeth; Greulich, Heidi; Bø, Trond Hellem; Jonassen, Inge; Thomas, Roman K.; Zander, Tim; Garraway, Levi A.; Øyan, Anne Margrete; Sellers, William R.; Kalland, Karl-Henning; Meyerson, Matthew; Akslen, Lars A.; Beroukhim, Rameen. 2009. Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation. Proceedings of the National Academy of Science of the United States of America. 106: 4834-4839. doi: 10.1073/pnas.0806514106
Wik, Elisabeth; Trovik, Jone; Iversen, Ole-Erik; Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Vestrheim, LC; Haugland, Hans K.; Akslen, Lars A.; Salvesen, Helga Birgitte. 2009. Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting. American Journal of Obstetrics and Gynecology. 201: 603-607. doi: 10.1016/j.ajog.2009.07.029

Akslen, Lars A.; Naumov, George N. 2008. Tumor dormancy - from basic mechanisms to clinical practice. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 116: 545-547. doi: 10.1111/j.1600-0463.2008.01209.x
Akslen, Lars A.; Puntervoll, Hanne Eknes; Bachmann, Ingeborg M.; Straume, Oddbjørn; Vuhahula, Edda; Kumar, Rajiv; Molven, Anders. 2008. Mutation analysis of the EGFR-NRAS-BRAF pathway in melanomas from black Africans and other subgroups of cutaneous melanoma. Melanoma research. 18: 29-35.
Arnes, Jarle; Collett, Karin; Akslen, Lars A. 2008. Lesson of the Month - Independent prognostic value of the basal-like phenotype of breast cancer and associations with EGFR and candidate stem cell marker BMI-1. Histopathology. 52: 370-380. doi: 10.1111/j.1365-2559.2007.02957.x
Arnes, Jarle; Foulkes, William D.; Akslen, Lars A. 2008. Candidate stem cell marker ALDH1 expression and relationship with BRCA-mutations and basal-like differentiation in breast carcinoma. Histopathology. 53: 25-25.
Bachmann, Ingeborg M.; Ladstein, Rita Grude; Straume, Oddbjørn; Naumov, GN; Akslen, Lars A. 2008. Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas. BMC Cancer. 8: 362-372. doi: 10.1186/1471-2407-8-362
Bachmann, Ingeborg M.; Puntervoll, Hanne Eknes; Otte, Arie P.; Akslen, Lars A. 2008. Loss of BMI-1 expression is associated with clinical progress of malignant melanoma. Modern Pathology. 21: 583-590. doi: 10.1038/modpathol.2008.17
Borkamo, Erling Dahl; Fluge, Øystein; Mella, Olav; Akslen, Lars A.; Bruland, Ove; Dahl, Olav. 2008. Hyperthermia improves the antitumour effect of metronomic cyclophosphamide in a rat transplantable brain tumour. Radiotherapy and Oncology. 86: 435-442. doi: 10.1016/j.radonc.2008.01.022
Dutt, Amit; Salvesen, Helga; Chent, Tzu-Hsiu; Ramos, Alex H.; Onofrio, Robert C.; Hatton, Charlie; Nicoletti, Richard; Winckler, Wendy; Grewal, Rupinder; Hanna, Megan; Wyhs, Nicolas; Ziaugra, Liuda; Richter, Daniel J.; Trovik, Jone; Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Fennell, Tim; Cibulskis, Kristian; Zody, Michael C.; Akslen, Lars A.; Gabriel, Stacey; Wong, Kwok-Kin; Sellers, William R.; Meyerson, Matthew; Greulich, Heidi. 2008. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proceedings of the National Academy of Science of the United States of America. 105: 8713-8717. doi: 10.1073/pnas.0803379105
Engelsen, Ingeborg Bøe; Mannelqvist, Monica; Stefansson, Ingunn Marie; Carter, Scott L.; Beroukhim, Rameen; Øyan, Anne Margrete; Otte, Ariel P.; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga. 2008. Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma. British Journal of Cancer. 98: 1662-1669. doi: 10.1038/sj.bjc.6604360
Engelsen, Ingeborg Bøe; Stefansson, IM; Akslen, Lars A.; Salvesen, Helga Birgitte. 2008. GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival. American Journal of Obstetrics and Gynecology. 199: e 1-7. doi: 10.1016/j.ajog.2008.04.043
Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Beroukhim, Rameen; Sellers, William R.; Meyerson, Matthew; Akslen, Lars A.; Salvesen, Helga. 2008. HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas. International Journal of Oncology. 32: 307-316.
Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2008. Vascular proliferation by Nestin/Ki-67 is a novel predictor of the clinical progress of prostate cancer. Histopathology. 53: 276-277.
Helsing, Per; Nyrnoen, Dag André; Ariansen, Sarah; Steine, Solrun; Mæhle, Lovise; Aamdal, Steinar; Langmark, Frøydis; Loeb, Mitchell; Akslen, Lars A.; Molven, Anders; Andresen, Per Arild Kjølseth. 2008. Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas. Genes, Chromosomes and Cancer. 47: 175-184. doi: 10.1002/gcc.20518
Ke, Xisong; Qu, Yi; Goldfinger, Naomi; Rostad, Kari; Hovland, Randi; Akslen, Lars A.; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning. 2008. Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but without Malignant Transformation. PLoS ONE. 3. doi: 10.1371/journal.pone.0003368
Lin, Biaoyang; Utleg, Angelita G.; Gravdal, Karsten; White, James T.; Halvorsen, Ole Johan; Lu, Wei; True, Lawrence D.; Vessella, Robert; Lange, Paul H.; Nelson, Peter S.; Hood, Leroy; Kalland, Karl-Henning; Akslen, Lars A. 2008. WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence. Clinical Cancer Research. 14: 1397-1406. doi: 10.1158/1078-0432.CCR-07-1535
Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2008. Expression of EGFR and c-kit is associated with the basal-like phenotype in breast carcinomas of African women. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 116: 515-525. doi: 10.1111/j.1600-0463.2008.01024.x
Naumov, George N.; Folkman, Judah; Straume, Oddbjørn; Akslen, Lars A. 2008. Tumor-vascular interactions and tumor dormancy. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 116: 569-585. doi: 10.1111/j.1600-0463.2008.01213.x
Naumov, George N.; Heymach, John; Akslen, Lars A. 2008. Dr. Folkman's legacy - a life of angiogenesis research. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 116: 89-92. doi: 10.1111/j.1600-0463.2008.00123.x

Bachmann, Ingeborg M.; Eknes, HE; Otte, Ariel P.; Akslen, Lars A. 2007. Loss of BMI-1 expression is associated with the clinical progress of malignant melanoma. Virchows Archiv. 451: 452-452.
Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2007. A Switch from E-Cadherin to N-Cadherin Expression Indicates Epithelial to Mesenchymal Transition and Is of Strong and Independent Importance for the Progress of Prostate Cancer. Clinical Cancer Research. 13: 7003-7011. doi: 10.1158/1078-0432.CCR-07-1263
Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2007. Epithelial to mesenchymal transition is of strong prognostic importance in prostate cancer. Virchows Archiv. 451: 344-344.
Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Puntervoll, Hanne Eknes; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2007. Increased expression of sim2-s protein is a novel marker of aggressive prostate cancer. Clinical Cancer Research. 13: 892-897. doi: 10.1158/1078-0432.CCR-06-1207
Nalwoga, H; Arnes, Jarle; Wabinga, H; Akslen, Lars A. 2007. Basal-like phenotype is frequent in invasive breast carcinoma from Ugandan Africans and is strongly associated with a high expression of EGFR/c-Kit and features of aggressive tumors. Virchows Archiv. 451: 137-137.
Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2007. Frequency of the basal-like phenotype in African breast cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 115: 1391-1399. doi: 10.1111/j.1600-0463.2007.00862.x
Naumov, George N.; Watnick, Randolph S.; Almog, Nava; Akslen, Lars A.; Folkman, Judah. 2007. Re: A model of human tumor dormancy: An angiogenic escape from the nonangiogenic phenotype - Response. Journal of the National Cancer Institute. 99: 331-332. doi: 10.1093/jnci/djk056
Petersen, Kjell; Øyan, Anne Margrete; Rostad, Kari; Olsen, Sue; Bø, Trond Hellem; Salvesen, Helga; Gjertsen, Bjørn Tore; Bruserud, Øystein; Halvorsen, Ole Johan; Akslen, Lars A.; Steen, Vidar Martin; Jonassen, Inge; Kalland, Karl-Henning. 2007. Comparison of nucleic acid targets prepared from total RNA or poly(A) RNA for DNA oligonucleotide microarray hybridization. Analytical Biochemistry. 366: 46-58. doi: 10.1016/j.ab.2007.03.013
Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2007. ERG upregulation and related ETS transcription factors in prostate cancer. International Journal of Oncology. 30: 19-32.
Tischkowitz, Marc; Brunet, Jean-Sébastien; Bégin, Louis R.; Huntsman, David G.; Cheang, Maggie C.U.; Akslen, Lars A.; Nielsen, Torsten O.; Foulkes, William D. 2007. Use of immunohistochemical markers can refine prognosis in triple negative breast cancer. BMC Cancer. 7. 11 pages. doi: 10.1186/1471-2407-7-134

Bachmann, Ingeborg Margrethe; Halvorsen, Ole Johan; Collett, Karin; Stefansson, Ingunn Marie; Straume, Oddbjørn; Haukaas, Svein Andreas; Salvesen, Helga; Otte, Arie P.; Akslen, Lars A. 2006. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. Journal of Clinical Oncology. 24: 268-273. doi: 10.1200/JCO.2005.01.5180
Collett, Karin; Eide, Geir Egil; Arnes, Jarle; Stefansson, Ingunn Marie; Eide, Johan; Braaten, Audun; Aas, Turid; Otte, Ariel P.; Akslen, Lars A. 2006. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clinical Cancer Research. 12: 1168-1174. doi: 10.1158/1078-0432.CCR-05-1533
Engeland, Anders; Tretli, Steinar; Akslen, Lars Andreas; Bjørge, Tone. 2006. Body size and thyroid cancer in two million Norwegian men and women. British Journal of Cancer. 95: 366-370. doi: 10.1038/sj.bjc.6603249
Engelsen, Ingeborg; Stefansson, Ingunn Marie; Akslen, Lars A.; Salvesen, Helga. 2006. Pathologic expression of p53 or p16 in preoperative curettage specimens identifies high-risk endometrial carcinomas. American Journal of Obstetrics and Gynecology. 195: 979-986.
Fluge, Øystein; Bruland, Ove; Akslen, Lars A.; Lillehaug, Johan; Varhaug, Jan Erik. 2006. Gene expression in poorly differentiated papillary thyroid carcinomas. Thyroid. 16: 161-175.
Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2006. Expression of bFGF/FGFR-1 and vascular proliferation related to clinicopathologic features and tumor progress in localized prostate cancer. Virchows Archiv. 448: 68-74.
Haukaas, Svein Andreas; Halvorsen, Ole Johan; Dæhlin, Lars; Høstmark, Jens; Akslen, Lars A. 2006. Is preoperative serum prostate-specific antigen level significantly related to clinical recurrence after radical 14 retropubic prostatectomy for localized prostate cancer? BJU International. 97: 51-55. doi: 10.1111/j.1464-410X.2006.05886
Kalland, Karl-Henning; Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2006. Global gene expression analysis of transcription factors in prostate cancer and cell lines. International Journal of Molecular Medicine. 18: S27. Published 2006-10-14.
Naumov, George N.; Akslen, Lars A.; Folkman, Judah. 2006. Role of angiogenesis in human tumor dormancy - Animal models of the angiogenic switch. Cell Cycle. 5: 1779-1787.
Naumov, George N.; Bender, Elise; Zurakowski, David; Kang, Soo-Young; Sampson, David; Flynn, Evelyn; Watnick, Randolph S.; Straume, Oddbjørn; Akslen, Lars A.; Folkman, Judah; Almog, Nava. 2006. A model of human tumor dormancy: An angiogenic switch from the nonangiogenic phenotype. Journal of the National Cancer Institute. 98: 316-325. doi: 10.1093/jnci/djj068
Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Ulvestad, Elling; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2006. ERG upregulation in relation to other transcription factors in prostate cancer. NBS-nytt. 1: 72.
Stefansson, Ingunn Marie; Salvesen, Helga; Akslen, Lars A. 2006. Loss of p63 and cytokeratin 5/6 expression is associated with more aggressive tumors in endometrial carcinoma patients. International Journal of Cancer. 118: 1227-1233. doi: 10.1002/ijc.21415
Stefansson, Ingunn Marie; Salvesen, Helga; Akslen, Lars A. 2006. Vascular proliferation is important for clinical progress of endometrial cancer. Cancer Research. 66: 3303-3309.
Sørlie, Therese; Perou, Charles M.; Fan, Cheng; Geisler, Stephanie; Aas, Turid; Nobel, Andrew; Anker, Gun; Akslen, Lars A.; Botstein, David; Børresen-Dale, Anne-Lise; Lønning, Per Eystein. 2006. Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer. Molecular Cancer Therapeutics. 5: 2914-2918. doi: 10.1158/1535-7163.MCT-06-0126

Akslen, Lars A.; Angelini, Sabrina; Straume, Oddbjørn; Molven, Anders; Bachmann, Ingeborg; Hemminki, Kari; Kumar, Rajiv. 2005. BRAF and NRAS mutations are frequent in nodular melanoma but are not associated with tumor cell proliferation or patient survival. Journal of Investigative Dermatology. 125: 312-317.
Bachmann, Ingeborg; Straume, Oddbjørn; Puntervoll, Hanne Eknes; Kalvenes, May Britt; Akslen, Lars A. 2005. Importance of P-cadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clinical Cancer Research. 11: 8606-8614. doi: 10.1158/1078-0432.CCR-05-0011
Collett, Karin; Stefansson, Ingunn Marie; Eide, Johan; Braaten, Audun; Wang, Hege; Eide, Geir Egil; Thoresen, Steinar Østerbø; Thoresen, Steinar; Foulkes, William D.; Akslen, Lars A. 2005. A basal epithelial phenotype is more frequent in interval breast cancers compared with screen detected tumors. Cancer Epidemiology, Biomarkers and Prevention. 14: 1108-1112.
Gjengstø, Peder; Paus, Elisabeth; Halvorsen, OJ; Eide, J; Akslen, LA; Wentzel-Larsen, T; Hoisaeter, PA. 2005. Predictors of prostate cancer evaluated by receiver operating characteristics partial area index: a prospective institutional study. Journal of Urology. 173: 425-428.
Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2005. Single-minded 2 homolog gene is overexpressed in prostate cancer. Virchows Archiv. 447: 432-432.
Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Rostad, Kari; Haukaas, Svein Andreas; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Stordrange, Laila; Lin, Biaoyang; Jonassen, Inge; Hood, Leroy; Akslen, Lars A.; Kalland, Karl-Henning. 2005. Gene expression profiles in prostate cancer: Association with patient subgroups and tumour differentiation. International Journal of Oncology. 26: 329-336.
Kalland, Karl-Henning; Halvorsen, Ole Johan; Rostad, Kari; Mannelqvist, Monica; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2005. Overexpression of ERG and SIM2 transcription factors in prostate cancer. International Journal of Molecular Medicine. 16: S76-S76.
Molven, Anders; Grimstvedt, Magne B.; Steine, Solrun; Harland, Mark; Avril, Marie-Françoise; Hayward, Nicholas K.; Akslen, Lars A. 2005. A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation. Genes, Chromosomes and Cancer. 44: 10-18. doi: 10.1002/gcc.20202
Salvesen, Helga; Kumar, Rajiv; Stefansson, Ingunn Marie; Angelini, Sabrina; MacDonald, Nicola; Smeds, Johanna; Jacobs, Ian J.; Hemminki, Kari; Das, Soma; Akslen, Lars A. 2005. Low frequency of BRAF and CDKN2A mutations in endometrial cancer. International Journal of Cancer. 115: 930-934. doi: 10.1002/ijc.20702
Sharma, Praveen; Sahni, Narinder S; Tibshirani, Robert; Skaane, Per; Skaane, P; Urdal, Petter; Berghagen, Hege; Jensen, Maianne; Kristiansen, Lena; Moen, Cecilie; Sharma, Pradeep; Zaka, Alia; Arnes, Jarle; Sauer, Torill; Sauer, Toril; Akslen, Lars A; Schlichting, Ellen; Børresen-Dale, Anne-Lise; Lönneborg, Anders. 2005. Early detection of brest cancer based on gene-expression patterns in peripheral blood cells. Breast Cancer Research. 7: R634-R644. doi: 10.1186/bcr1203
Sharma, Praveen; Sahni, Narinder S; Tibshirani, Robert; Skaane, Per; Urdal, Petter; Berghagen, Hege; Jensen, Marianne; Moen, Cecilie; Kristiansen, Lena; Sharma, Pradeep; Zaka, Alia; Arnes, Jarle; Sauer, Torill; Akslen, Lars A.; Schlichting, Ellen; Børresen-Dale, Anne-Lise; Lönneborg, Anders. 2005. Early detection of breast cancer based on gene-expression patterns in peripheral blood cells. Breast Cancer Research. 7: 634-644. doi: 10.1186/bcr1203
Straume, Oddbjørn; Akslen, Lars A. 2005. Strong expression of ID1 protein is associated with decreased survival, increased expression of ephrin-A1/EPHA2, and reduced thrombospondin-1 in malignant melanoma. British Journal of Cancer. 93: 933-938. doi: 10.1038/sj.bjc.6602792

Akslen, Lars A.; Jacobsen, GK; Vainio, O. 2004. Angiogenesis - recent developments in molecular pathogenesis, morphological markers, and therapeutic applications. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 112: 399-401.
Bachmann, Ingeborg; Straume, Oddbjørn; Akslen, Lars A. 2004. Altered expression of cell cycle regulators Cyclin D1, p14, p16, CDK4 and Rb in nodular melanomas. International Journal of Oncology. 25: 1559-1565.
Eikesdal, Hans Petter; Straume, Oddbjørn; Akslen, Lars A.; Dahl, Olav. 2004. Karnydanning og tumorkar som mål for kreftterapi. Tidsskrift for Den norske legeforening. 124: 1919-1922.
Foulkes, WD; Akslen, Lars A. 2004. Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer. Journal of the National Cancer Institute. 96: 714.
Foulkes, WD; Brunet, JS; Stefansson, Ingunn Marie; Straume, Oddbjørn; Chappuis, PO; Begin, LR; Hamel, N; Goffin, JR; Wong, N; Trudel, M; Kapusta, L; Porter, P; Akslen, Lars A. 2004. The prognostic implication of the basal-like (cyclin E-high/p27(low)/p53(+)/glomeruloid-microvascular-proliferation(+)) phenotype of BRCA1-related breast cancer. Cancer Research. 64: 830-835.
Macdonald, ND; Salvesen, Helga; Ryan, A; Malatos, S; Stefansson, Ingunn Marie; Iversen, Ole-Erik; Akslen, Lars A.; Das, S; Jacobs, IJ. 2004. Molecular differences between RER+ and RER- sporadic endometrial carcinomas in a large population-based series. International Journal of Gynecological Cancer. 14: 957-965.
Nielsen, TO; Hsu, FD; Jensen, K; Cheang, M; Karaca, G; Hu, Z; Hernandez-Boussard, T; Livasy, C; Cowan, D; Dressler, L; Akslen, Lars A.; Ragaz, J; Gown, AM; Gilks, CB; Van de Rijn, M; Perou, CM. 2004. Immunohistochemical and Clinical Characterization of the Basal-like Subtype of Invasive Breast Carcinoma. Clinical Cancer Research. 10: 5367-5374.
Salvesen, Helga; Stefansson, Ingunn Marie; Kretzschmar, EI; Gruber, P; Macdonald, ND; Ryan, A; Jacobs, IJ; Akslen, Lars A.; Das, S. 2004. Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression. International Journal of Oncology. 25: 1615-1623.
Stefansson, Ingunn Marie; Salvesen, Helga; Akslen, Lars A. 2004. Prognostic impact of histological grade and vascular invasion compared with tumor cell proliferation in endometrial carcinoma of endometrioid type. Histopathology. 44: 472-479.
Stefansson, Ingunn Marie; Salvesen, Helga; Akslen, Lars A. 2004. Prognostic impact of alterations in P-cadherin expression and related cell adhesion markers in endometrial cancer. Journal of Clinical Oncology. 22: 1242-1252.
Straume, Oddbjørn; Akslen, Lars A. 2004. Lymphatic vessel density and prognosis in cutaneous melanoma. British Journal of Cancer. 91: 1224-1225.

Aas, Turid; Geisler, Stephanie; Eide, Geir Egil; Haugen, Dagny R. Faksvåg; Varhaug, Jan Erik; Bassøe, Anne Margrethe; Thorsen, Thor; Berntsen, Hildegunn; Børresen-Dale, AL; Akslen, Lars A.; Lønning, Per Eystein. 2003. Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy. European Journal of Cancer. 39: 438-446.
Alexander-Sefre, F; Salvesen, Helga B.; Abeler, N; Singh, N; Akslen, Lars A.; MacDonald, N; Wilbanks, G; Jacobs, IJ. 2003. Molecular assessment of depth of myometrial invasion in stage I endometrial cancer: a model based on K-ras mutation analysis. Gynecologic Oncology. 91: 218-25.
Foulkes, WD; Stefansson, Ingunn Marie; Chappuis, PO; Begin, LR; Goffin, JR; Wong, N; Trudel, M; Akslen, Lars A. 2003. Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. Journal of the National Cancer Institute. 95: 1482-85.
Geisler, Stephanie; Børresen-Dale, Anne-Lise; Johnsen, Hilde; Aas, Turid; Geisler, Jürgen; Akslen, Lars A.; Anker, Gun; Lønning, Per Eystein. 2003. TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer. Clinical Cancer Research. 9: 5582-5588.
Gjengstø, Peder; Halvorsen, Ole J.; Akslen, Lars A.; Frugård, Jannicke; Høisæter, Per Åge. 2003. Benign growth of different prostate zones in aging men with slightly elevated PSA in whom prostate cancer has been excluded: a prospective study of 510 patients. Urology. 62: 447-450.
Halford, SE; Sawyer, EJ; Lambros, MB; Gorman, P; MacDonald, ND; Talbot, IC; Foulkes, WD; Gillett, CE; Barnes, DM; Akslen, Lars A.; Lee, K; Jacobs, IJ; anby, AM; Ganesan, TS; Salvesen, Helga B.; Bodner, WF; Tomlinson, IP; Roylance, RR. 2003. MSI-low, a real phenomenon which varies in frequency among cancer types. Journal of Pathology. 201: 389-94.
Halvorsen, Ole J.; Haukaas, Sven; Akslen, Lars A. 2003. Combined loss of PTEN and p27 expression is associated with tumor cell proliferation by Ki-67 and increased risk of recurrent disease in localized prostate cancer. Clinical Cancer Research. 9: 1474-1479.
Salvesen, Helga B.; Gulluoglu, Mine G; Stefansson, Ingunn Marie; Akslen, Lars A. 2003. Significance of CD 105 expression for tumour angiogenesis and prognosis in endometrial carcinomas. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 111: 1011-1018.

Paessler, M; Kreisel, FH; Livolsi, VA; Akslen, Lars A.; Baloch, ZW. 2002. Can we rely on pathologic parameters to define conservative treatment of papillary thyroid carcinoma? International Journal of Surgical Pathology. 10: 267-272.
Salvesen, Helga B.; Stefansson, Ingunn Marie; Kalvenes, May Britt; Das, S; Akslen, Lars A. 2002. Loss of PTEN expression is associated with metastatic disease in patients with endometrial carcinoma. Cancer. 94: 2185-91.
Salvesen, Helga Birgitte; Akslen, Lars A. 2002. Molecular pathogenesis and prognostic factors in endometrial carcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 110: 673-689. doi: 10.1034/j.1600-0463.2002.1101001.x
Stefansson, Ingunn Marie; Akslen, Lars A.; MacDonald, N; Ryan, A; Das, S; Jacobs, IJ; Salvesen, Helga B. 2002. Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study. Clinical Cancer Research. 8: 138-43.

Fluge, Øystein; Haugen, Dagny R. Faksvåg; Akslen, Lars A.; Marstad, Anne; Santoro, Massimo; Fusco, Alfredo; Varhaug, Jan Erik; Lillehaug, Johan. 2001. Expression and alternative splicing of c-ret RNA in papillary thyroid carcinomas. Oncogene. 20: 885-892.
Frich, Lars; Glattre, Eystein; Akslen, Lars A. 2001. Familial occurrence of nonmedullary thyroid cancer: a population-based study of 5673 first-degree relatives of thyroid cancer patients from Norway. Cancer Epidemiology, Biomarkers and Prevention. 10: 113-117.
Halvorsen, Ole J.; Haukaas, Sven; Høisæter, Per Åge; Akslen, Lars A. 2001. Maximum Ki-67 staining in prostate cancer provides independent prognostic information after radical prostatectomy. Anticancer Research. 21. 7 pages.
Mbonde, MP; Amir, H; Akslen, Lars A.; Kitinya, JN. 2001. Expression of oestrogen and progesterone receptorss, Ki-67, p53 and BCL-2 proteins, cathepsin D, urokinase plasminogen activator and urokinase plasminogen activator-receptors in carcinomas of the female breast in an African poplation. East African Medical Journal. 78: 360-5.

Perou, CM; Sørlie, T; Eisen, MB; van de Rijn, M; Jeffrey, SS; Rees, CA; Pollack, JR; Ross, DT; Johnsen, H; Akslen, Lars A.; Fluge, Øystein; Pergamenschikov, A; Williams, C; Zhu, SX; Lønning, Per Eystein; Børresen-Dale, Anne-Lise; Brown, PO; Botstein, D. 2000. Molecular portraits of human breast tumours. Nature. 406: 747-52.
Vuhahula, E; Straume, Oddbjørn; Akslen, Lars A. 2000. Frequent loss of p16 protein expression and high proliferative activity (Ki-67) in malignant melanoma from black Africans. Anticancer Research. 20: 4857-62.

Das, S; MacDonald, N; Ryan, A; Jacobs, IJ; Lynch, ED; Akslen, Lars A.; Salvesen, Helga. 1999. The PTEN gene is methylated in endometrial carcinoma and associated with advanced disease and microsattelite instability. (Abs. no. 207). American Journal of Human Genetics. 65: S. 209.
Geisler, Stephanie; Lønning, Per Eystein; Aas, T; Johnsen, H; Fluge, Ø; Haugen, Dagny R. Faksvåg; Lillehaug, Johan; Akslen, Lars A.; Børresen-Dale, AL. 1999. Influence of TP53 gene alterations and Her-2 expression on the respons to treatment with doxorubicin in locally advanced breast cancer. (Abs. no. 227). Breast Cancer Research and Treatment. 57.
Haugen, Dagny R. Faksvåg; Lillehaug, JR; Akslen, Lars A. 1999. Enhanced expression of EGF-receptor and low frequency of ras mutations in X-ray-induced rat thyroid tumours. Virchows Archiv. 435: 434-441.
Hove, Leif M; Akslen, Lars A. 1999. Clinicopathological characteristics of melanomas of the hand. Journal of Hand Surgery - British and European Volume. 24B: 460-64.
Hove, Leif M; Akslen, Lars A. 1999. Clinicopathological characteristics of melanomas of the hand. Journal of Hand Surgery - British and European Volume. 15: 460-64.
Lønning, Per Eystein; Johnsen, H; Geisler, Stephanie; Aas, T; Smith-Sørensen, B; Akslen, Lars A.; Børresen-Dale, AL. 1999. TP53 as a predictor of response to chemotherpy in breast cancer. RSO Scientific Updates. 4: 73-88.
Lønning, Per Eystein; Johnsen, H; Geisler, Stephanie; Aas, Turid; Smith-Sørensen, B; Akslen, Lars A.; Børresen-Dale, AL. 1999. TP53 as a predictor of response to chemotherapy in breast cancer. European School of Oncology Scientific Updates. 4: 73-88.
Salvesen, Helga; Akslen, Lars A. 1999. Strong prognostic influence of reduced p16 protein expression in endometrial carcinomas. A large population based study. (Abstract no. 0-079). Virchows Archiv. 435: 185.
Salvesen, Helga; Akslen, Lars A. 1999. Significance of tumor associated macrophages, VEGF and TSP-1 for angiogenesis and prognosis of endometrial carcinoma. International Journal of Cancer. 84: 538-43.
Salvesen, Helga; Akslen, Lars A. 1999. Significance of tumor associated macrophages. VEGF and TSP-1 expression for tumor angiogenesis and prognosis in endometrial carcinomas. International Journal of Cancer. 84: 539-543.
Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1999. Prognostic significance of angiogenesis, Ki-67, p53 and p21 expression - a population-based endometrial carcinoma study. International Journal of Oncology. 15: 395-399.
Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1999. Prognostic value of tumor angiogenesis, Ki67, p53 and p21 protein expression - a population based endometrial carcinoma study. Journal of Clinical Oncology. 15: 595-99.
Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1999. Prognostic significance of tumor angiogenesis, Ki-67, p53 and p21 expression - a population-based endometrial carcinoma study. Journal of Clinical Oncology. 17: 1382-1390.
Straume, Oddbjørn; Akslen, Lars A. 1999. Loss of nuclear expression of p16 protein correlates with increased tumor cell proliferation and poor patient outcome in patients with vertical growth phase melanoma. (Abstract no. P-487). Virchows Archiv. 435: 314.
Straume, Oddbjørn; Salvesen, Helga; Akslen, Lars A. 1999. Angiogenesis is prognostically important in vertical growth phase melanomas. International Journal of Oncology. 15: 595-599.

Akslen, Lars A.; Monstad, S. E.; Larsen, B.; Straume, O.; Øgreid, D. 1998. Frequent mutations of the p53 gene in cutaneous melanoma of the nodular type. International Journal of Cancer. 79: 91-95.
Heuch, Jane M.; Heuch, Ivar; Akslen, Lars A.; Kvåle, Gunnar. 1998. Risk of primary childhood brain tumors related to birth characteristics: a Norwegian prospective study. International Journal of Cancer. 77: 498-503.

Book sections

Akslen, Lars A. 2008. Pathology of Breast Tumors in Hereditary Breast Cancer. Section 5: Cliical Management of Heredidtary Breast Cancer, Chapter 18, pages 319-332. In:
- Isaacs, Claudine; Rebbeck, Timothy R. 2008. Hereditary Breast Cancer. 400 pages. ISBN: 978-0-8493-9022-7.

More information in national current research information system (CRIStin)