Lars Bø's picture
Lars
Bø
Adjunct Professor
Visit Address: 
Haukeland Universitetssykehus Laboratoriebygget, 7. etg. Heis øst
5021 Bergen
Postal Address: 
Postboks 7804
5021 Bergen
E-mail: 
Lars.Bo@k1.uib.no
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Journal articles
  • Lunde, Hanne Marie; Telstad, Wenche; Torkildsen, Nina Agnethe Grytten; Kyte, Lars; Aarseth, Jan; Myhr, Kjell-Morten; Bø, Lars. 2014. Employment among patients with multiple sclerosis-A population study. PLoS ONE. 9. doi: 10.1371/journal.pone.0103317
  • Fjær, Sveinung; Bø, Lars; Lundervold, Arvid; Myhr, Kjell-Morten; Pavlin, Tina; Torkildsen, Øivind; Wergeland, Stig. 2013. Deep gray matter demyelination detected by magnetization transfer ratio in the cuprizone model. PLoS ONE. 8. doi: 10.1371/journal.pone.0084162
  • Lunde, Hanne Marie; Bjorvatn, Bjørn; Myhr, Kjell-Morten; Bø, Lars. 2013. Clinical assessment and management of sleep disorders in multiple sclerosis: a literature review. Acta Neurologica Scandinavica, Supplementum. 127: 24-30. doi: 10.1111/ane.12046
  • Lunde, Hanne Marie; Aae, Tommy F; Indrevåg, William; Aarseth, Jan Harald; Myhr, Kjell-Morten; Bjorvatn, Bjarne; Bø, Lars. 2012. Poor sleep in patients with multiple sclerosis. European Journal of Neurology. 19: 706-706. doi: 10.1371/journal.pone.0049996
  • Lunde, Hanne Marie; Aae, Tommy Frøseth; Indrevåg, William; Aarseth, Jan Harald; Bjorvatn, Bjørn; Myhr, Kjell-Morten; Bø, Lars. 2012. Poor Sleep in Patients with Multiple Sclerosis. PLoS ONE. 7. 5 pages. doi: 10.1371/journal.pone.0049996
  • Myhr, Kjell-Morten; Grytten, Nina Agnethe; Torkildsen, Øivind; Wergeland, Stig; Bø, Lars; Pugliatti, M; Aarseth, Jan Harald. 2012. A need for national registries and international collaborative research in multiple sclerosis. Acta Neurologica Scandinavica. 126: 1-3. doi: 10.1111/ane.12039
  • Wergeland, Stig; Torkildsen, Øivind; Bø, Lars; Myhr, Kjell-Morten. 2012. Polyunsaturated fatty acids in multiple sclerosis therapy. Acta Neurologica Scandinavica. 126: 70-75. doi: 10.1111/ane.12034
  • Wergeland, Stig; Torkildsen, Øivind; Myhr, Kjell-Morten; Mørk, Sverre; Bø, Lars. 2012. The cuprizone model: regional heterogeneity of pathology. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 120: 648-657. doi: 10.1111/j.1600-0463.2012.02882.x
  • Wergeland, Stig; Torkildsen, Øivind; Myhr, Kjell-Morten; Aksnes, Lage; Mørk, Sverre; Bø, Lars. 2011. Dietary vitamin D3 supplements reduce demyelination in the cuprizone model. PLoS ONE. 6. 8 pages. doi: 10.1371/journal.pone.0026262
  • Tallantyre, Emma C.; Bø, Lars; Al-Rawashdeh, Omar; Owens, Trudy; Polman, Chris H.; Lowe, James; Evangelou, Nikos. 2010. Clinico-pathological evidence that axonal loss underlies disability in progressive multiple sclerosis. Multiple Sclerosis. 16: 406-411. doi: 10.1177/1352458510364992
  • Torkildsen, Øivind Fredvik; Stansberg, Christine; Angelskår, Solveig Mjelstad; Kooi, Evert-Jan; Geurts, Jeroen J.G.; van der Valk, Paul; Myhr, Kjell-Morten; Steen, Vidar Martin; Bø, Lars. 2010. Upregulation of immunoglobulin-related genes in cortical sections from multiple sclerosis patients. Brain Pathology. 20: 720-729. doi: 10.1111/j.1750-3639.2009.00343.x
  • Bø, Lars. 2009. The histopathology of grey matter demyelination in multiple sclerosis. Acta Neurologica Scandinavica. 120: 51-57. doi: 10.1111/j.1600-0404.2009.01216.x
  • Gilmore, Christopher P.; DeLuca, GC; Bø, Lars; Owens, Trudy; Lowe, James; Esiri, MM; Evangelou, Nikos. 2009. Spinal Cord Neuronal Pathology in Multiple Sclerosis. Brain Pathology. 19: 642-649. doi: 10.1111/j.1750-3639.2008.00228.x
  • Gilmore, Christopher P.; Donaldson, I; Bø, Lars; Owens, Trudy; Lowe, J; Evangelou, Nikos. 2009. Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord. Journal of Neurology, Neurosurgery and Psychiatry. 80: 182-187. doi: 10.1136/jnnp.2008.148767
  • Gilmore, Christopher P.; Geurts, Jeroen J.G.; Evangelou, Nikos; Bot, Joost C.J.; van Schijndel, Ronald A.; Pouwels, Petra J.W; Barkhof, Frederik; Bø, Lars. 2009. Spinal cord grey matter lesions in multiple sclerosis detected by post-mortem high field MR imaging. Multiple Sclerosis. 15: 180-188. doi: 10.1177/1352458508096876
  • Kooi, Evert-Jan; Geurts, Jeroen J.G.; van Horssen, Jack; Bø, Lars; van der Valk, Paul. 2009. Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 68: 1021-1028.
  • Kooi, Evert-Jan; van Horssen, Jack; Witte, Maarten; Amor, Sandra; Bø, Lars; Dijkstra, Christine D.; van der Valk, Paul; Geurts, Jeroen J.G. 2009. Abundant extracellular myelin in the meninges of patients with multiple sclerosis. Neuropathology and Applied Neurobiology. 35: 283-295. doi: 10.1111/j.1365-2990.2008.00986.x
  • Tallantyre, Emma C.; Bø, Lars; Al-Rawashdeh, Omar; Owens, Trudy; Polman, Chris H.; Lowe, James; Evangelou, Nikos. 2009. Greater loss of axons in primary progressive multiple sclerosis plaques compared to secondary progressive disease. Brain. 132: 1190-1199. doi: 10.1093/brain/awp106
  • Tallantyre, Emma C.; Bø, Lars; Lowe, James; Evangelou, Nikos. 2009. Equal loss of corticospinal axons despite less demyelination in primary vs secondary progressive multiple sclerosis. Neuropathology and Applied Neurobiology. 35: 17-18.
  • Torkildsen, Øivind Fredvik; Brunborg, Linn Anne; Milde, Anne Marita; Mørk, Sverre; Myhr, Kjell-Morten; Bø, Lars. 2009. A salmon based diet protects mice from behavioural changes in the cuprizone model for demyelination. Clinical Nutrition. 28: 83-87. doi: 10.1016/j.clnu.2008.10.015
  • Torkildsen, Øivind Fredvik; Brunborg, Linn Anne; Thorsen, Frits Alan; Mørk, Sverre; Stangel, Martin; Myhr, Kjell-Morten; Bø, Lars. 2009. Effects of dietary intervention on MRI activity, de- and remyelination in the cuprizone model for demyelination. Experimental Neurology. 215: 160-166. doi: 10.1016/j.expneurol.2008.09.026
  • Wergeland, Stig; Torkildsen, Øivind Fredvik; Myhr, Kjell-Morten; Mørk, Sverre; Bø, Lars. 2009. Histopathological characterisation of the cuprizone model for demyelination. Multiple Sclerosis. 15: S177-S177.
  • Witte, Maarten; Bø, Lars; Rodenburg, Richard J.; Belien, JA; Musters, Rene; Smeitink, Jan A.; Geurts, J; de Vries, Helga E.; van der Valk, Paul; Horssen, J. 2009. MITOCHONDRIAL ALTERATIONS IN ASTROCYTES IN MS LESIONS. Glia. 57: S134-S134.
  • Witte, Maarten; Bø, Lars; Rodenburg, Richard J.; Belien, Jeroen A.; Musters, Rene; Hazes, Thierry; Wintjes, Liesbeth T.; Smeitink, Jan A.; Geurts, Jeroen J.G.; de Vries, Helga E.; van der Valk, Paul; van Horssen, Jack. 2009. Enhanced number and activity of mitochondria in multiple sclerosis lesions. Journal of Pathology. 219: 193-204. doi: 10.1002/path.2582
  • Breij, Esther C.W.; Brink, Bianca P.; Veerhuis, Rob; Van den Berg, Christa; Vloet, Rianka; Yan, Riqiang; Dijkstra, Christine D.; van der Valk, Paul; Bø, Lars. 2008. Homogeneity of active demyelinating lesions in established multiple sclerosis. Annals of Neurology. 63: 16-25. doi: 10.1002/ana.21311
  • Breij, Esther C.W.; Brink, Bianca P.; Veerhuis, Rob; Van den Berg, Christa; Vloet, Rianka; Yan, Riqiang; Dijkstra, Christine D.; van der Valk, Paul; Bø, Lars. 2008. A homogeneous pattern of active demyelination in patients with established multiple sclerosis. Journal of Neuroimmunology. 203: 264-265.
  • Couturier, Nicholas; Zappulla, Jacques P.; Lauwers-Cances, Valérie; Uro-Coste, Emmanuelle; Delisle, Marie-Bernadette; Clanet, Michel; Montagne, Lisette; van der Valk, Paul; Bø, Lars; Liblau, Roland S. 2008. Mast cell transcripts are increased within and outside multiple sclerosis lesions. Journal of Neuroimmunology. 195: 176-185. doi: 10.1016/j.jneuroim.2008.01.017
  • Kooi, Evert-Jan; Bø, Lars; van Horssen, Jack; Geurts, Jeroen J.G.; van der Valk, Paul. 2008. Meningeal inflammation in multiple sclerosis. Multiple Sclerosis. 14: S273-S274. doi: 10.1177/1352458508096399
  • Kooi, Evert-Jan; van Horssen, Jack; Witte, Maarten; Amor, Sandra; Bø, Lars; Dijkstra, Christine D.; van der Valk, Paul; Geurts, Jeroen J.G. 2008. Extensive myelin deposition in the meninges of patients with multiple sclerosis. Multiple Sclerosis. 14: S273-S273. doi: 10.1177/1352458508096399
  • Torkildsen, Øivind Fredvik; Brunborg, Linn Anne Bjelland; Milde, Anne Marita; Myhr, Kjell-Morten; Bø, Lars. 2008. Fish diet prevents impaired mobility in the murine cuprizone model for multiple sclerosis. Multiple Sclerosis. 14: S90-S91. doi: 10.1177/1352458508096399
  • Torkildsen, Øivind Fredvik; Brunborg, Linn Anne Bjelland; Myhr, Kjell-Morten; Bø, Lars. 2008. The cuprizone model for demyelination. Acta Neurologica Scandinavica. 117: 72-76. doi: 10.1111/j.1600-0404.2008.01036.x
  • Bø, Lars; Geurts, Jeroen J.G.; van der Valk, Paul; Polman, Chris; Barkhof, Frederik. 2007. Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis. Archives of Neurology. 64: 76-80.
  • Geurts, Jeroen J.G.; Bø, Lars; Bö, Lars; Roosendaal, Stefan D; Hazes, Thierry; Daniëls, Richard; Barkhof, Frederik; Witter, Menno P; Huitinga, Inge; van der Valk, Paul. 2007. Extensive hippocampal demyelination in multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 66: 819-827.
  • van Horssen, Jack; Brink, Bianca P.; de Vries, Helga E.; van der Valk, Paul; Bø, Lars. 2007. The blood-brain barrier in cortical multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 66: 321-328.
  • Bø, Lars; Mørk, Sverre; Geurts, Jeroen J.G.; van der Valk, Paul. 2006. Grey matter pathology in multiple sclerosis. Acta Neurologica Scandinavica. 113: 48-50.
  • Bø, Lars; Vedeler, C.; Nyland, Harald Inge; Trapp, B.D.; Mørk, Sverre. 2003. Intracortical demyelination in multiple sclerosis is not associated with increased lymphocyte infiltration. Mult Scler. 9: 323-331.
  • Bø, Lars; Vedeler, C.; Nyland, Harald Inge; Trapp, Bruce D.; Mørk, Sverre. 2003. Subpial demyelination in the cerebral cortex of multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 62: 723-732.
  • Peterson, J.W; Bø, Lars; Mørk, Sverre; Chang, A; Ransohoff, RM; Trapp, B.D. 2002. VCAM-1-positive microglia target oligodendrycytes at the border of multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 61: 539-546.
  • Romi, Fredrik; Bø, Lars; Skeie, Geir Olve; Myking, Andreas O.; Aarli, Johan Arild; Gilhus, Nils Erik. 2002. Titin and ryanodine receptor epitopes are expressed in cortical thymoma along with co-stimulatory molecules. Journal of Neuroimmunology. 128: 82-89.
  • Peterson, John W.; Bø, Lars; Mørk, Sverre; Chang, Ansi; Trapp, Bruce D. 2001. Transected Neurites, Apoptotic Neurons and Reduced Inflammation in Cortical MS Lesions. Annals of Neurology. 50: 389-400.
  • Trapp, BD; Bø, Lars; Mørk, Sverre; Chang, A. 1999. Pathogenesis of tissue injury in MS lesions. Neuroimmunomodulation. 98: 49-56.
Reports and theses
  • Bø, Lars. 1998. Multiple sclerosis, immunopathological studies of inflammatory control nervous system demyelination. Dr.med.. -.

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