Nicolas Delaleu's picture
Nicolas
Delaleu
Researcher
Visit Address: 
Haukeland universitetssykehus, Laboratoriebygget
5021 Bergen
Postal Address: 
Postboks 7804
5021 Bergen
Phone: 
+47 55 97 46 64
Home Page
E-mail: 
Nicolas.Delaleu@k2.uib.no
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Profiles from http://www.nicolasdelaleu.ch

Researcher: http://www.nicolasdelaleu.ch/pages/researcher.html 

Photographer: http://www.nicolasdelaleu.ch/pages/photographer.html

Climber: http://www.nicolasdelaleu.ch/pages/climber.html

 

  • Immunology & autoimmune diseases
  • Systems biology & bioinformatics
  • Experimental models of autoimmunity
  • Applied biomarker research and saliva diagnostics
  • FACS & cell and tissue cultures
  • Advanced microscopy & molecular biology
Journal articles
  • Delaleu, Nicolas; Nguyen, Cuong Q; Tekle, Kidane M; Jonsson, Roland; Peck, Ammon B. 2013. Transcriptional landscapes of emerging autoimmunity: transient aberrations in the targeted tissue's extracellular milieu precede immune responses in Sjogren's syndrome. Arthritis Research & Therapy. 15. doi: 10.1186/ar4362
  • Ledahl, Suzanne; Vogelsang, Petra; Jonsson, Roland; Lycke, Nils; Delaleu, Nicolas. 2013. Modulation of experimental Sjögren's Syndrome and diabetes via mucosal vaccination with fusion proteins derived from cholera-toxin and heat shock protein 60 kDa. Scandinavian Journal of Immunology. 77: 321-321.
  • Ledahl, Suzanne Lovise; Vogelsang, Petra; Jonsson, Roland; Lycke, Nils Y.; Delaleu, Nicolas. 2012. Modulation of experimental Sjögren's syndrome and diabetes via mucosal vaccination with fusion proteins derived from cholera-toxin and heat shock protein 60 kDa. Immunology. 137: 766-766. doi: 10.1111/imm.12002
  • Delaleu, Nicolas; Peck, AB. 2009. Autoimmunity: limited progress for the patient, despite decades of research. Scandinavian Journal of Immunology. 70: 411-414. doi: 10.1111/j.1365-3083.2009.02318.x
  • Delaleu, Nicolas; Immervoll, Heike; Cornelius, Janet; Jonsson, Roland. 2008. Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations. Arthritis Research & Therapy. 10. 14 pages. doi: 10.1186/ar2375
  • Delaleu, Nicolas; Jonsson, Malin V; Appel, Silke; Jonsson, Roland. 2008. New Concepts in the Pathogenesis of Sjogren's Syndrome. Rheumatic Disease Clinics of North America. 34: 833-+. doi: 10.1016/j.rdc.2008.08.004
  • Delaleu, Nicolas; Madureira, Ana Carina; Immervoll, Heike; Jonsson, Roland. 2008. Inhibition of experimental Sjögren's syndrome through immunization with Hsp60 and its peptide amino acids 437-460. Arthritis and Rheumatism. 58: 2318-2328. doi: 10.1002/art.23656
  • Delaleu, Nicolas; Madureira, Ana Carina; Immervoll, Heike; Jonsson, Roland. 2008. Inhibition of experimental Sjögren's syndrome through immunization with heat-shock protein 60kDa and its peptide aa437-460. Arthritis and Rheumatism. 58: S795-S795.
  • Jonsson, Malin V; Delaleu, Nicolas; Jonsson, Roland. 2007. Animal models of Sjögren's syndrome. Clinical reviews in allergy and immunology. 32: 215-224. doi: 10.1007/s12016-007-8012-7
  • Berggreen, Ellen; Nyløkken, Krister; Delaleu, Nicolas; Jonsson, Malin V; Hajdaragic-Ibricevic, Hamieta. 2006. Impaired vascular responses to parasympathetic stimulation in the submandibular gland in NOD mice. Arthritis and Rheumatism. 54: S709-S709.
  • Jonsson, Malin V; Delaleu, Nicolas; Brokstad, Karl Albert; Berggreen, Ellen; Skarstein, Kathrine. 2006. Impaired salivary gland function in nod mice - Association with changes in cytokine profile but not with salivary gland histopathology. Arthritis and Rheumatism. 54: S707-S707.
  • Jonsson, Malin V; Delaleu, Nicolas; Brokstad, Karl Albert; Berggreen, Ellen; Skarstein, Kathrine. 2006. Impaired salivary gland function in NOD mice - Association with changes in cytokine profile but not with histopathologic changes in the salivary gland. Arthritis and Rheumatism. 54: 2300-2305. doi: 10.1002/art.21945
  • Delaleu, Nicolas; Jonsson, Roland; Koller, Markus M. 2005. Sjögren's syndrome. European Journal of Oral Sciences. 113: 101-113.
  • Szodoray, Peter; Alex, Phillip; Jonsson, Malin V; Knowlton, Nicholas; Dozmorov, Igor; Nakken, Britt; Delaleu, Nicolas; Jonsson, Roland; Centola, Mike. 2005. Distinct profiles of Sjögren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF. Clinical Immunology. 117: 168-176. doi: 10.1016/j.clim.2005.06.016
  • Delaleu, Nicolas; Jonsson, Malin V; Jonsson, Roland. 2004. Disease mechanisms of Sjögren's syndrome. Drug Discovery Today. 1: 329-336.
Book sections
  • Jonsson, Malin V; Delaleu, Nicolas; Cuida Marthinussen, Ileana Mihaela; Jonsson, Roland. 2011. Oral and Dental Manifestations of Sjögren's Syndrome: Current Approaches to Diagnostics and Therapy. 15, pages 221-242. In:
    • Fox, Robert I; Fox, Carla M. 2011. Sjögren's Syndrome Practical Guidelines to Diagnosis and Therapy. Springer. 505 pages. ISBN: 978-1-60327-956-7.

More information in national current research information system (CRIStin)

 

Peer-reviewed articles:

http://www.nicolasdelaleu.ch/pages/peerreviewed_articles.html

 

Book chapters:

http://www.nicolasdelaleu.ch/pages/book_chapters.html

 

Dissertation for the degree philosophiae doctor:

http://www.nicolasdelaleu.ch/pages/dissertation.html

 

Popular scientific articles:

http://www.nicolasdelaleu.ch/pages/popular_science.html

Current projects
  • Investigate the prophylactic and therapeutic effect of intranasal CTA1R7K-DD-associated peptide delivery in spontaneous experimental models of Sjögren’s syndrome.
  • Salivary biomarker profiles in the diagnosis and classification of rheumatic diseases.
  • The development of system biology-based and bioinformatics-assisted analyses strategies to allow comprehensive mapping of changes in biological states with a maximum of standardization and minimal introduction of bias.
  • Higher level data integration of multidimensional and global datasets.