Rolf
Bjerkvig
Professor
Visit Address:
Jonas Lies vei 91
5020 Bergen
Postal Address:
Postboks 7800
5020 Bergen
Phone:
+47 55 58 63 52
+47 951 18 268
E-mail:
Books
- 2005. Cell encapsulation therapy for malignant gliomas. Springer. 16 pages.
- 1998. Brain Tumor Invasion: Clinical, Biological and Therapeutic Considerations.
- 1998. Brain Tumor Invasion: Clinical, Biological and Therapeutic Considerations.
- 1998. Brain Tumor Invasion: Clinical, Biological and Therapeutic Consideration. ISBN: 0-471-15452-0.
- 1998. Brain Tumor Invasion. Biological, Clinical and Therapeutic Considerations. John Wiley & Sons.
- 1998. Brain Tumor Invasion. Biological, Clinical and Therapeutic Considerations. John Wiley & Sons.
- 1998. Brain Tumor Invasion: Biological, Clinical and Therapeutic Considerations. ISBN: 0-471-15452-0.
- 1998. Brain tumor invasion: Biological, clinical, and therapeutic considerations. John Wiley & Sons.
Journal articles
- 2014. In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways. International Journal of Molecular Sciences. 15: 8773-8794. doi: 10.3390/ijms15058773
- 2014. Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes. Acta Neuropathologica. 127: 203-219. doi: 10.1007/s00401-013-1196-4
- 2014. Glutamate as chemotactic fuel for diffuse glioma cells: Are they glutamate suckers? Biochimica et Biophysica Acta. CR. Reviews on Cancer. 1846: 66-74. doi: 10.1016/j.bbcan.2014.04.004
- 2013. In vivo animal models for studying brain metastasis: value and limitations. Clinical and Experimental Metastasis. 30: 695-710. Published 2013-01-16. doi: 10.1007/s10585-013-9566-9
- 2013. Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome Sequencing. PLoS ONE. 8. 11 pages. doi: 10.1371/journal.pone.0076623
- 2013. ACTIVATION OF THE PROTOTYPICAL SFK c-Src PROMOTES ANGIOGENESIS OF HUMAN GLIOBLASTOMA. Neuro-Oncology. 15: 3-3.
- 2013. GLIOBLASTOMA ADAPTATION TO ANTI-VASCULAR THERAPY INVOLVES AN UP-REGULATION OF GLYCOLYSIS WHERE LACTATE DEHYDROGENASE (LDH) REPRESENTS A POTENTIAL THERAPEUTIC TARGET. Neuro-Oncology. 15: 7-7.
- 2013. Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells. Brain. 136: 1462-1475. doi: 10.1093/brain/awt025
- 2013. CLONAL EVOLUTION MEETS CANCER STEM CELLS IN GLIOBLASTOMA. Neuro-Oncology. 15: 208-209.
- 2013. The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells. Neuro-Oncology. 15: 269-278. doi: 10.1093/neuonc/nos301
- 2013. Tumor vasculature: the Achilles' heel of cancer? Expert opinion on therapeutic targets. 17: 7-20. doi: 10.1517/14728222.2013.730522
- 2013. A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. PLoS ONE. 8: e59773. doi: 10.1371/journal.pone.0059773
- 2013. Gene set based integrated data analysis reveals phenotypic differences in a brain cancer model. PLoS ONE. 8. 11 pages. doi: 10.1371/journal.pone.0068288
- 2013. Expansive growth of two glioblastoma stem-like cell lines is mediated by bFGF and not by EGF. Radiology and Oncology. 47: 330-337. doi: 10.2478/raon-2013-0063
- 2013. Cathepsin L silencing enhances arsenic trioxide mediated in vitro cytotoxicity and apoptosis in glioblastoma U87MG spheroids. Experimental Cell Research. 319: 2637-2648. doi: 10.1016/j.yexcr.2013.08.011
- 2013. DISTINCT FUNCTIONAL ROLES OF WILD-TYPE EGFR AND ITS MUTANT EGFRvIII IN GLIOBLASTOMA DEVELOPMENT. Neuro-Oncology. 15: 6-6.
- 2013. Automated tracking of nanoparticle-labeled melanoma cells improves the predictive power of a brain metastasis model. Cancer Research. 73: 2445-2456. Published 2013-04-15. doi: 10.1158/0008-5472.CAN-12-3514
- 2013. BRAIN-SPECIFIC GENE SIGNATURE OF MELANOMA METASTASIS. Neuro-Oncology. 15: 27-27.
- 2013. Tumor versus stromal cells in culture-survival of the fittest? PLoS ONE. 8. 12 pages. doi: 10.1371/journal.pone.0081183
- 2013. EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. Neuro-Oncology. 15: 6-6.
- 2013. EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. Acta Neuropathologica. 125: 683-698. doi: 10.1007/s00401-013-1101-1
- 2013. Mesenchymal stem cell signaling in cancer progression. Cancer Treatment Reviews. 39: 180-188. doi: 10.1016/j.ctrv.2012.03.005
- 2013. Loss of adipocyte specification and necrosis augment tumor-associated inflammation. Adipocyte. 2: 176-183. doi: 10.4161/adip.24472
- 2012. Differential tumor-stroma interactions in glioblastoma. Neuro-Oncology. 14: 13-13. doi: 10.1093/neuonc/nos183
- 2012. METABOLIC ANALYSIS OF GLIOBLASTOMA XENOGRAFTS AFTER ANTI-ANGIOGENIC TREATMENT. Neuro-Oncology. 14: 58-58.
- 2012. The regulation of cysteine cathepsins and cystatins in human gliomas. International Journal of Cancer. 131: 1779-1789. doi: 10.1002/ijc.27453
- 2012. SIDE POPULATION IN HUMAN GLIOBLASTOMA DOES NOT CHARACTERIZE CANCER STEM CELL POPULATIONS AND IS EXCLUSIVELY STROMA-DERIVED. Neuro-Oncology. 14: 42-43.
- 2012. In vivo models of primary brain tumors: pitfalls and perspectives. Neuro-Oncology. 14: 979-993. doi: 10.1093/neuonc/nos135
- 2012. Molecular mechanisms of temozolomide resistance in glioblastoma multiforme. Expert Review of Anticancer Therapy. 12: 635-642. doi: 10.1586/ERA.12.37
- 2012. The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling. Blood. 120: 847-857. doi: 10.1182/blood-2011-10-388496
- 2012. Comment to: "Spontaneous transformation of adult mesenchymal stem cells from cynomolgus macaques in vitro" by Z. Ren et al. Exp. Cell Res. 317 (2011) 2950-2957, Spontaneous transformation of mesenchymal stem cells in culture: Facts or fiction? Experimental Cell Research. 318: 441-443. doi: 10.1016/j.yexcr.2011.12.009
- 2012. Spontaneous Transformation of Stem Cells In Vitro and the Issue of Cross-Contamination. International Journal of Biological Sciences. 8: 1051-1052. doi: 10.7150/ijbs.3665
- 2012. Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI. Journal of Nuclear Medicine. 53: 1135-1145. doi: 10.2967/jnumed.111.101659
- 2012. Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis. Angiogenesis. 15: 481-495. doi: 10.1007/s10456-012-9276-y
- 2011. Differential Activity of NADPH-Producing Dehydrogenases Renders Rodents Unsuitable Models to Study IDH1(R132) Mutation Effects in Human Glioblastoma. Journal of Histochemistry and Cytochemistry. 59: 489-503. doi: 10.1369/0022155411400606
- 2011. Optimising Treatment In Gliomas - Translational. European Journal of Cancer. 47: S63-S64.
- 2011. A novel and clinically relevant mouse model reflecting the disease progression in melanoma brain metastasis in patients. Clinical and Experimental Metastasis. 28: 238-238.
- 2011. Molecular imaging and genetic studies reveal selective homing of human brain metastatic cells to various organs in NOD/SCID mice. Clinical and Experimental Metastasis. 28: 194-194.
- 2011. Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases. Journal of Cancer Research and Clinical Oncology. 137: 399-414. doi: 10.1007/s00432-010-0888-6
- 2011. NUMB does not impair growth and differentiation status of experimental gliomas. Experimental Cell Research. 317: 2864-2873. doi: 10.1016/j.yexcr.2011.09.002
- 2011. Critical appraisal of the side population assay in stem cell and cancer stem cell research. Cell Stem Cell. 8: 136-147. doi: 10.1016/j.stem.2011.01.007
- 2011. Separate analysis of the cancer and stroma cell populations from orthotopically implanted tumor biopsies in eGFP scid mice. Clinical and Experimental Metastasis. 28: 203-203.
- 2011. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proceedings of the National Academy of Science of the United States of America. 108: 3749-3754. doi: 10.1073/pnas.1014480108
- 2011. Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma. Acta Neuropathologica. 122: 495-510. doi: 10.1007/s00401-011-0867-2
- 2011. Treatment of Solid Cancers Using a New Cationic Cytolytic Peptide. European Journal of Cancer. 47: S148-S148.
- 2011. A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients. Neuropathology and Applied Neurobiology. 37: 189-205. doi: 10.1111/j.1365-2990.2010.01119.x
- 2011. Targeting the NG2/CSPG4 Proteoglycan Retards Tumour Growth and Angiogenesis in Preclinical Models of GBM and Melanoma. PLoS ONE. 6. 14 pages. doi: 10.1371/journal.pone.0023062
- 2010. Cancer stem cells: current controversies. European Journal of Cancer. 8: 5-5.
- 2010. NG2 PROMOTES RESISTANCE TO IONIZING RADIATION BY ELEVATED PEROXIREDOXIN-1 AND DNA DAMAGE RESPONSE IN GLIOBLASTOMA MULTIFORME. Neuro-Oncology. 12: 8-8.
- 2010. Immunohistochemical expression of stem cell, endothelial cell, and chemosensitivity markers in primary glioma spheroids cultured in serum-containing and serum-free medium. Neurosurgery. 66: 933-947. doi: 10.1227/01.NEU.0000368393.45935.46
- 2010. A NOVEL PATIENT MELANOMA BRAIN METASTASIS MODEL DEVELOPED IN NOD-SCID MICE REFLECTS THE CLINICAL METASTATIC DISEASE PROGRESSION IN PATIENTS. Neuro-Oncology. 12: 135-136.
- 2010. Ciliary Neurotrophic Factor Cell-Based Delivery Prevents Synaptic Impairment and Improves Memory in Mouse Models of Alzheimer's Disease. Journal of Neuroscience. 30: 7516-7527. doi: 10.1523/JNEUROSCI.4182-09.2010
- 2010. CANCER STEM CELLS IN GLIOBLASTOMA, WHAT ARE THEY? Neuro-Oncology. 12: 123-123.
- 2010. CANCER STEM CELLS IN GLIOBLASTOMA, WHAT ARE THEY? Neuro-Oncology. 12: 40-40.
- 2010. alpha B-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells. American Journal of Pathology. 177: 1618-1628. doi: 10.2353/ajpath.2010.090063
- 2010. Successful engraftment of glioblastoma biopsy spheroids in immunocompetent rats. European Journal of Cancer. 8: 76-76.
- 2010. Cellular effects of oncolytic viral therapy on the glioblastoma microenvironment. Gene Therapy. 17: 202-216. doi: 10.1038/gt.2009.130
- 2010. APPLICATION OF A NOVEL P53 REPORTER ASSAY IN HUMAN GLIOBLASTOMA CELLS. Neuro-Oncology. 12: 96-96.
- 2010. Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein. BMC Molecular Biology. 11. 12 pages. doi: 10.1186/1471-2199-11-89
- 2010. ANTI-ANGIOGENIC TREATMENT IN A CLINICALLY RELEVANT GLIOBLASTOMA MODEL REDUCES BLOOD FLOW AND INCREASES TUMOR CELL INVASION. Neuro-Oncology. 12: 20-20.
- 2010. NESTIN-EXPRESSING CELLS IN TUMOR ANGIOGENESIS. Neuro-Oncology. 12: 6-6.
- 2010. Glioma cell populations grouped by different cell type markers drive brain tumor growth. Cancer Research. 70: 4274-4279. doi: 10.1158/0008-5472.CAN-09-3904
- 2010. FUNCTIONAL VALIDATION OF NOVEL MOLECULAR TARGETS FOR ANTI-ANGIOGENIC TREATMENT OF MALIGNANT GLIOMAS. Neuro-Oncology. 12: 49-49.
- 2010. HIGH-RESOLUTION GENOMIC PROFILING OF XENOGRAFTED HUMAN GLIOMAS TO DELINEATE NONANGIOGENIC AND HIGHLY ANGIOGENIC PHENOTYPES IN A CLINICALLY RELEVANT MODEL SYSTEM. Neuro-Oncology. 12: 48-48.
- 2010. FLOW SORT ARRAY COMPARATIVE GENOMIC HYBRIDIZATION TO ASSESS TUMOR HETEROGENEITY IN GLIOBLASTOMA. Neuro-Oncology. 12: 66-67.
- 2010. A new lytic peptide for the treatment of cancer. European Journal of Cancer. 8: 58-59.
- 2010. Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter. Cancer Research. 70: 6393-6396. doi: 10.1158/0008-5472.CAN-10-1305
- 2010. Interstitial fluid: the overlooked component of the tumor microenvironment? Fibrogenesis & tissue repair. 3. Published 2010-07-23. doi: 10.1186/1755-1536-3-12
- 2009. BRAIN TUMOR INITIATION AND DEVELOPMENT, INFLUENCE OF CANCER STEM-LIKE CELLS. Neuro-Oncology. 11: 874-874.
- 2009. Cancer stem cells and angiogenesis. Seminars in Cancer Biology. 19: 279-284. doi: 10.1016/j.semcancer.2009.09.001
- 2009. Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy. PLoS ONE. doi: 10.1371/journal.pone.0006314
- 2009. Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype. Neuropathology and Applied Neurobiology. 35: 380-393. doi: 10.1111/j.1365-2990.2009.01008.x
- 2009. Cell-cycle regulation and dynamics of cytoplasmic compartments containing the promyelocytic leukemia protein and nucleoporins. Journal of Cell Science. 122: 1201-1210. doi: 10.1242/jcs.040840
- 2009. Lentiviral Vectors Mediate Efficient Suicide Gene Therapy in an Invasive Xenograft Model of Human Glioblastoma. Molecular Therapy. 17: S302-S302.
- 2009. Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms. Expert opinion on therapeutic targets. 13: 455-468. doi: 10.1517/14728220902806444
- 2009. PHENOTYPIC AND PHYSIOLOGIC EFFECTS OF BEVACIZUMAB IN A HIGHLY INFILTRATIVE AND ANGIOGENIC HUMAN GLIOBLASTOMA MODEL. Neuro-Oncology. 11: 906-906.
- 2009. MOLECULAR VARIATIONS IN TUMOR-HOST INTERACTIONS BETWEEN INVASIVE AND ANGIOGENIC PHENOTYPE IN HIGH-GRADE GLIOMAS. Neuro-Oncology. 11: 961-961.
- 2009. iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype. Molecular & Cellular Proteomics. 8: 2595-2612. doi: 10.1074/mcp.M900124-MCP200
- 2009. Long-term cultures of bone marrow-derived human mesenchymal stem cells frequently undergo spontaneous malignant transformation. Cancer Research. 69: 5331-5339. doi: 10.1158/0008-5472.CAN-08-4630
- 2009. Activated Platelets Provide a Functional Microenvironment for the Antiangiogenic Fragment of Histidine-Rich Glycoprotein. Molecular Cancer Research. 7: 1792-1802. doi: 10.1158/1541-7786.MCR-09-0094
- 2009. PHENOTYPIC MODULATION OF EXPERIMENTAL GLIOMAS: PROGRESSION FROM GLIOMATOSIS CEREBRI-LIKE LESIONS TO GLIOBLASTOMA. Neuro-Oncology. 11: 897-897.
- 2009. A reproducible brain tumour model established from human glioblastoma biopsies. BMC Cancer. 9. doi: 10.1186/1471-2407-9-465
- 2009. Targeting the tumor stroma: a novel therapeutic strategy based on separate analysis of the malignant and stromal cell compartments in brain tumors. Neuro-Oncology. 11: 221-222.
- 2009. TARGETING THE TUMOR STROMA: A NOVEL THERAPEUTIC STRATEGY BASED ON SEPARATE ANALYSIS OF THE MALIGNANT AND STROMAL CELL COMPARTMENTS IN BRAIN TUMORS. Neuro-Oncology. 11: 965-965.
- 2008. The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. Oncogene. 27: 5182-5194. doi: 10.1038/onc.2008.157
- 2008. Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma. Clinical Cancer Research. 14: 1571-1580. doi: 10.1158/1078-0432.CCR-07-2000
- 2008. Human glioblastoma tissue engraftment in immunocompetent rodent hosts. Neuro-Oncology. 10: 815-815. doi: 10.1215/15228517-2008-051
- 2008. DNA repair and cancer stem-like cells - Potential partners in glioma drug resistance? Cancer Treatment Reviews. 34: 558-567. doi: 10.1016/j.ctrv.2008.03.125
- 2008. Efficient suicide gene therapy with lentiviral pseudotyped vectors in an invasive xenograft model of human glioblastoma. Neuro-Oncology. 10: 797-798.
- 2008. Host cell recruitment by gliomas. European Journal of Cancer. 6: 71-72. doi: 10.1016/S1359-6349(08)71447-2
- 2008. COMPLETE SEPARATION AND PHENOTYPING OF THE TUMOR-HOST CELLULAR COMPARTMENTS IN TUMOR-BEARING NOD/SCID MICE. Neuro-Oncology. 10: 853-854.
- 2008. Complete separation and phenotyping of the tumor-host cellular compartments in tumor bearing nod/scid mice. Neuro-Oncology. 10: 1148-1148.
- 2008. A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions. The FASEB Journal. 22: 3120-3128. doi: 10.1096/fj.08-109611
- 2008. Amplifying small amounts of tumor DNA allows detection of DNA copy number abberations with array-CGH. BioTechniques. 44: S3-S6.
- 2008. DEVELOPMENT OF A NEW BRAIN METASTASES MODEL IN IMMUNODEFICIENT ANIMALS. Neuro-Oncology. 10: 854-854.
- 2008. Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics. NMR in Biomedicine. 21: 830-838. Published 2008-10-21. doi: 10.1002/nbm.1263
- 2008. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. International Journal of Cancer. 122: 761-768. doi: 10.1002/ijc.23130
- 2007. New approaches to treatment of brain cancer. Anticancer Research. 27: 1375-1375.
- 2007. Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres. Nucleic Acids Research. 35: 7267-7278. doi: 10.1093/nar/gkm738
- 2007. Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres. Nucleic Acids Research. 35: 7267-7278.
- 2007. Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors. BMC Cancer. 7. 10 pages. doi: 10.1186/1471-2407-7-23
- 2007. Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats. Journal of Neuro-Oncology. 85: 191-202. doi: 10.1007/s11060-007-9407-2
- 2007. Lymphangiogenesis in colorectal cancer - Prognostic and therapeutic aspects. International Journal of Cancer. 121: 1401-1409. doi: 10.1002/ijc.22996
- 2007. Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery. Journal of Neuro-Oncology. 82: 1-10. doi: 10.1007/s11060-006-9240-z
- 2007. Cancer initiation and progression: Involvement of stem cells and the micro environment. Biochimica et Biophysica Acta. CR. Reviews on Cancer. 1775: 283-297. doi: 10.1016/j.bbcan.2007.01.001
- 2006. NG2 expression regulates vascular morphology and function in human brain tumours. NeuroImage. 29: 965-976. doi: Se sammendrag
- 2006. Promyelocytic leukemia nuclear bodies are predetermined processing sites for damaged DNA. Journal of Cell Science. 119: 3284-3295. doi: 10.1242/jcs.03068
- 2006. Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. Cancer Research. 66: 9895-9902. doi: 10.1158/0008-5472.CAN-05-4589
- 2006. Antitumor efficacy improved by local delivery of species-specific endostatin. Journal of Neurosurgery. 104: 118-128.
- 2006. Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1. Neuro-Oncology. 8: 96-108. doi: 10.1215/15228517-2005-006
- 2006. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proceedings of the National Academy of Science of the United States of America. 103: 16466-16471. doi: 10.1073/pnas.0607668103
- 2006. Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation. Neuropathology and Applied Neurobiology. 32: 419-427. doi: 10.1111/j.1365-2990.2006.00744.x
- 2006. Cell therapies for glioblastoma. Expert Opinion on Biological Therapy. 6: 739-749. doi: 10.1517/14712598.6.8.739
- 2006. Adeno-associated virus (AAV) serotypes 2, 4 and 5 display similar transduction profiles and penetrate solid tumor tissue in models of human glioma. Journal of Gene Medicine. 8: 1131-1140. doi: 10.1002/jgm.939
- 2006. Inhibition of medulloblastoma cell invasion by Slit. Oncogene. 25: 5103-5112. doi: 10.1038/sj.onc.1209524
- 2005. Opinion: the origin of the cancer stem cell: current controversies and new insights. Nature Reviews. Cancer. 5: 899-904. doi: 10.1038/nrc1740
- 2005. NG2 expression regulates vascular morphology and function in human brain tumours. NeuroImage. 29: 965-976. Published 2005-10-25. doi: 10.1016/j.neuroimage.2005.08.0
- 2005. Bacitracin inhibits glioma cell migration and invasion in vitro. Neuro-Oncology. 7: 357-357.
- 2005. Distribution patterns of the anti-angiogenic protein ADAMTS-1 during rat development. Acta Histochemica. 107: 121-131. doi: 10.1016/j.acthis.2004.07.009
- 2005. The brain slice chamber, a novel variation of the Boyden Chamber Assay, allows time-dependent quantification of glioma invasion into mammalian brain in vitro. Journal of Neuro-Oncology. 73: 9-18. doi: 10.1007/s11060-004-3341-3
- 2005. Slit2-Roundabout 1(Robo1) signaling inhibits medulloblastoma but not glioma cell invasion in three-dimensions. Neuro-Oncology. 7: 357-358.
- 2004. Angiogenesis-independent growth by brain tumor cells exhibiting cancer stem cell properties. Neuro-Oncology. 6: 309-309.
- 2004. Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival. Cancer Research. 64: 2105-2112.
- 2004. PML-nuclear bodies accumulate DNA in response to polyomavirus BK and simian virus 40 replication. Experimental Cell Research. 298: 58-73.
- 2004. Forced differentiation suppresses the proliferative rate of cancer cells in brain tumours. Neuro-Oncology. 6.
- 2004. Cryopreservation of alginate-encapsulated recombinant cells for antiangiogenic therapy. Cell Transplantation. 13: 35-44.
- 2004. Evidence for a secreted chemorepellent that directs glioma cell invasion. Journal of Neurobiology. 60: 71-88.
- 2003. Imaging of experimental rat gliomas using a clinical MR scanner. Journal of Neuro-Oncology. 63: 225-231.
- 2003. Cell therapy using encapsulated cells producing endostatin. Acta Neurochirurgica Supplementum. 88: 137-141.
- 2003. Cost of migration: invasion of malignant gliomas and implications for treatment. Journal of Clinical Oncology. 15: 1624-1636.
- 2003. Expression of extracellular matrix components in a highly infiltrative in vivo glioma model. Acta Neuropathologica. 105: 49-57.
- 2003. HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects. Advances in Cancer Research. 88: 1-29.
- 2003. Imaging of experimental rat gliomas using a clinical MR scanner. J Neurooncol. 63: 225-31.
- 2003. Mechanisms of tumor cell invasion and angiogenesis in the central nervous system. Frontiers in Bioscience. 8: e289-304.
- 2003. Prospects for delivery of recombinant angiostatin by cell-encapsulation therapy. Human Gene Therapy. 14: 1429-1440.
- 2003. Prospects for delivery of recombinant angiostatin by cell-encapsulation therapy. Human Gene Therapy. 14: 1429-1440.
- 2003. Loss of GFAP expression in high-grade astrocytomas does not contribute to tumor development or progression. Oncogene. 29: 3407-3411.
- 2002. NG2 proteoglycan promotes angiogenesis-dependent tumor growth in the central nervous system by sequestering angiostatin. The FASEB Journal. 16: 586-588.
- 2002. The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours. Neuropathology and Applied Neurobiology. 28: 367-380.
- 2002. NG2 proteoglycan promotes angiogenesis-dependent tumor growth in CNS by sequestering angiostatin. The FASEB Journal. 16: 586-588.
- 2002. Adeno-associated viral vectors penetrate human solid tumor tissue in vivo more effectively than adenoviral vectors. Human Gene Therapy. 13: 1115-1125.
- 2002. Localised delivery of therapeutic agents to CNS malignancies: old and new approaches. Current Pharmaceutical Biotechnology. 3: 257-273.
- 2002. Endostatin reduces intratumoral vascularization, blood flow and growth of gliosarcomas. Neuro-Oncology. 4: 1-8.
- 2001. Vinblastine and hyperthermia target the neovasculature in BT(4)AN rat gliomas: therapeutic implications of the vascular phenotype. International Journal of Radiation Oncology, Biology, Physics. 51: 535-544.
- 2001. Combretastatin A-4 and hyperthermia; a potent combination for the treatment of solid tumors. Radiotherapy and Oncology. 60: 147-154.
- 2001. Tumor vasculature is targeted by the combination of combretastatin A-4 and hyperthermia. Radiotherapy and Oncology. 61: 313-320.
- 2001. The glioma-associated gangliosides 3'-isoLM1, GD3 and GM2 show selective area expression in human glioblastoma xenografts in nude rat brains. Neuropathology and Applied Neurobiology. 27: 451-464.
- 2001. Intravital microscopy reveals novel antivascular and antitumor effects of endostatin delivered locally by alginate-encapsulated cells. Cancer Research. 15: 6830-6837.
- 2001. Local endostatin treatment of gliomas administered by microencapsulated producer cells. Nature Biotechnology. 19: 29-34.
- 2001. Local endostatin treatment of gliomas administered by microencapsulated producer cells. Nature Biotechnology. 1: 29-34.
- 2001. Bromelain reversibly inhibits invasive properties of glioma cells. Neoplasia. 2: 469-479.
- 2001. Cell encapsulation technology as a therapeutic strategy for CNS malignancies. Neuro-Oncology. 3: 201-210.
- 2000. Extracellular matrix-induced cell migration from glioblastoma biopsies in vitro. Acta Neuropathologica. 97 (3): 231-239.
- 2000. Herpes simplex thymidine kinase gene therapy in an experimental BT4C glioma model. Cancer Gene Therapy. 7: 413-421.
- 2000. Alginate encapsulated producer cells. A potential new approach for the treatment of malignant brain tumors. Cell Transplantation. 9: 773-783.
- 2000. LacZ transfected glioma cells in syngeneic rats: Growth pattern and characterization of the host immune response against cells transplanted inside and outside the CNS. International Journal of Cancer. 85: 228-235.
- 1999. Retroviral transfection of the LacZ gene from Liz 9 packing cells to glioma spheroids. International Journal of Developmental Neuroscience. 17: 665-672.
- 1999. Extracellular matrix-induced cell migration from gliobastoma biopsies in vitro. Acta Neuropathologica. 97: 231-39.
- 1999. Infection of Rat Brain Cell Aggregates with Neurovirulent and Nonneurovirulent Strains of Herpes Simplex Virus Type 1. Experimental Cell Research. 248: 306-313.
- 1998. Invasiveness by lacZ transfected non-small cell lung cancer cells into human bronchial tissues in vitro. Lung Cancer. 21: 7-19.
- 1998. Dynamic determination of human glioma invasion in vitro. Journal of Neurosurgery. 89: 441-447.
- 1998. Dynamic determination of human glioma invasion in vitro. Journal of Neurosurgery. 89: 441-447.
- 1997. Tumor cell invasion and angiogenesis in the central nervous system. Current Opinion in Oncology. 9: 223-229.
- 1997. Tumor cell invasion and angiogenesis in the central nervous system. Current Opinion in Oncology. 9: 223-229.
- 1997. Role of high molecular weight extracellular matrix proteins in glioma cell migration. Neuropathology and Applied Neurobiology. 23: 102-12.
- 1997. Glioma cell migration on extracellular components. Neuropathology and Applied Neurobiology. 23: 102-112.
- 1997. Proliferation, migration and invasion of human glioma cells exposed to paclitaxel (Taxol) in vitro. British Journal of Cancer. 75: 1744-1762.
- 1996. The lac-z reporter gene: a tool for in vitro studies of malignant glioma cell invasion. Invasion and Metastasis. 16: 107-115.
- 1996. Primary organ-culture of non neoplastic and neoplastic thyroid tissue as multicellular spheroids. International Journal of Oncology. 6: 1071-1078.
- 1996. Glioma cell invasion visualized by scanning confocal laser microscopy in an in vitro co-culture system. Inversion Metastasis. 15: 179-188.
- 1996. Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha 3 and anti-beta 1 integrin antibodies. International Journal of Cancer. 67: 777-784.
- 1996. Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha 3 and anti-beta 1 integrin antibodies. International Journal of Cancer. 67: 777-784.
- 1996. Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha 3 and anti-beta 1 integrin antibodies. International Journal of Cancer. 6: 1071-1078.
- 1995. Sensitive and rapid detection of _b-galactosidase expression in intact cells by microinjection of fluorescent substrate. Experimental Cell Research. 219: 372-378.
- 1995. Tumor fragment spheroids from human non-smal-cell lung cancer maintained in organ culture. Virchows Archiv. 426: 169-178.
- 1995. Kreftcellers spredning i hjernen. Naturen. 4. 151-156.
- 1995. Primary organ culture of non-neoplastic and neoplastic thyroid tissue multicellular spheroids. International Journal of Oncology. 6: 1071-1078.
- 1995. Primary organ culture of non-neoplastic and neoplastic thyroid tissue as multicellular spheroids. International Journal of Oncology. 6: 1071-1078.
- 1995. Primary organ culture of non-neoplastic and neoplastic thyroid tissue as multicellular spheroids. International Journal of Oncology. 6: 1071-1078.
- 1995. Migratory patterns of lacz transfected human glioma cells in the rat brain. International Journal of Cancer. 62: 767-771.
- 1995. Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells. Journal of Leukocyte Biology. 56: 732-740.
- 1995. Organ culture of a glioblastome from a patient with unusually long survival. Neurosurgery. 35: 428-432.
- 1994. Transfection of glioma cells with the neural-cell adhesion molecule NCAM: Effect on glioma cell invasion and growth in vivo. International Journal of Cancer. 58: 116-122.
- 1994. Transfection of glioma cells with the neural-cell adhesion molecule NCAM: Effect on glioma cell invasion and growth in vivo. International Journal of Cancer. 58: 116-122.
- 1994. Interactions between fetal rat brain cells and mature brain tissue in vivo and in vitro. Neuropathology and Applied Neurobiology. 20: 130-143.
- 1994. Interactions between fetal rat brain cells and mature brain tissue in vivo and in vitro. Neuropathology and Applied Neurobiology. 20: 130-143.
- 1994. Three-dimensional growth of glial cell lines affects growth factor and growth factor receptor mRNA levels. Experimental Cell Research. 214: 433-436.
Reports and theses
- 2009. Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype. Universitetet i Bergen.
- 2003. Mobiltelefon og helse. Najonalt folkehelseinstitutt, Oslo. 48 pages.
Book sections
- 1998. Glioma cell invasion studied in organotypic models. In:
- 1998. Brain Tumor Invasion: Biological, Clinical and Therapeutic Considerations. ISBN: 0-471-15452-0.
- 1996. Sensitive and rapid detection of B-galactosidase expression in intact cells by microinjection of fluorecent substrate. In:
- 1996. Fluorecence microscopy and fluorescent probes.
More information in national current research information system (CRIStin)