Rune
Kleppe
Researcher
Visit Address:
Jonas Lies vei 91
5009 Bergen
Postal Address:
Postboks 7804
5009 Bergen
Phone:
+47 55 58 64 52
E-mail:
Journal articles
- 2014. Functional studies of tyrosine hydroxylase missense variants reveal distinct patterns of molecular defects in dopa-responsive dystonia. Human Mutation. 35: 880-890. doi: 10.1002/humu.22565
- 2014. Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3. PLoS ONE. 9. doi: 10.1371/journal.pone.0094926
- 2014. Modelling cellular signal communication mediated by phosphorylation dependent interaction with 14-3-3 proteins. FEBS Letters. 588: 92-98. doi: 10.1016/j.febslet.2013.11.012
- 2014. Phosphorylation dependence and stoichiometry of the complex formed by tyrosine hydroxylase and 14-3-3γ. Molecular & Cellular Proteomics. 13: 2017-2030. doi: 10.1074/mcp.M113.035709
- 2014. Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. Biochemical and Biophysical Research Communications - BBRC. 449: 357-363. doi: 10.1016/j.bbrc.2014.05.032
- 2013. Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis. Cell Death & Disease. 4. doi: 10.1038/cddis.2013.39
- 2011. Nostocyclopeptide-M1: A potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and 1B1. Molecular Pharmaceutics. 8: 360-367. doi: 10.1021/mp1002224
- 2011. Cyclic AMP induces IPC leukemia cell apoptosis via CRE-and CDK-dependent Bim transcription. Cell Death and Differentiation. 2. 11 pages. doi: 10.1038/cddis.2011.124
- 2011. Dipyridamole synergizes with nitric oxide to prolong inhibition of thrombin-induced platelet shape change. Platelets. 22: 8-19. doi: 10.3109/09537104.2010.517581
- 2011. The cAMP-dependent protein kinase pathway as therapeutic target - possibilities and pitfalls. Current Topics in Medicinal Chemistry. 11: 1393-1405.
- 2011. The 14-3-3 proteins in regulation of cellular metabolism. Seminars in Cell and Developmental Biology. 22: 713-719. doi: 10.1016/j.semcdb.2011.08.008
- 2010. Dipyridamole synergizes with nitric oxide to prolong inhibition of thrombin-induced platelet shape change. Platelets. 22: 7-18. doi: 10.3109/09537104.2010.517581
- 2009. Three-way interaction between 14-3-3 proteins, the N-terminal region of tyrosine hydroxylase and negatively charged membranes. Journal of Biological Chemistry. 284: 32758-32769. doi: 10.1074/jbc.M109.027706
- 2008. Oxygen dependence of tyrosine hydroxylase. Amino Acids. 34: 455-464. doi: 10.1007/s00726-007-0547-7
- 2008. Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding. Biochemical Journal. 410: 195-204. doi: 10.1042/BJ20071033
- 2006. 14-3-3 proteins as substrates for cAMP-dependent protein kinase. European Journal of Pharmaceutical Sciences. 28: S27-S27.
- 2006. Does isoform diversity explain functional differences in the 14-3-3 protein family? Current Pharmaceutical Biotechnology. 7: 217-223. doi: 10.2174/138920106777549777
- 2006. Camp-dependent protein kinase. European Journal of Pharmaceutical Sciences. 28: S4-S5.
- 2006. Proteomic and computational methods in systems modeling of cellular signaling. Current Pharmaceutical Biotechnology. 7: 135-145. doi: 10.2174/138920106777549722
- 2004. Different stabilities and denaturation pathways for structurally related aromatic amino acid hydroxylases. FEBS Letters. 565: 155-159.
- 1999. Urea-induced denaturation of human phenylalanine hydroxylase. Journal of Biological Chemistry. 274: 33251-33258.
- 1999. Urea-induced denaturation of human phenylalanine hydroxylase. Journal of Biological Chemistry. 274: 33251-33258.
- 1995. Studies on the synthetic DNAs, repair replication, transcription and gene synthesis. Naturen. 1. 3-24.
Reports and theses
- 1998. A study on the thermodynamic stability of human phenylalanine hydroxylase. Hovedfagsoppgaver. Institutt for biokjemi og molekylærbiologi.
- 1998. A study on the thermodynamic stability of human phenylalanine hydroxylase. cand.scient.-oppgave. [Mangler utgivernavn]. 84 pages.
More information in national current research information system (CRIStin)