2012

Eur Cytokine Netw. 2012 Nov 1;23(4):140-53. doi: 10.1684/ecn.2012.0322.

The angioregulatory cytokine network in human acute myeloid leukemia - from leukemogenesis via remission induction to stem cell transplantation.

Reikvam H, Hatfield KJ, Fredly H, Nepstad I, Mosevoll KA, Bruserud O.

 

Blood. 2013 Feb 14;121(7):e34-42. doi: 10.1182/blood-2012-05-429555. Epub 2012 Dec 12.

Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia.

McCormack E, Mujic M, Osdal T, Bruserud O, Gjertsen BT.

 

Bone Marrow Res. 2012;2012:329061. doi: 10.1155/2012/329061. Epub 2012 Oct 2.

Inhibition of Mammalian target of rapamycin in human acute myeloid leukemia cells has diverse effects that depend on the environmental in vitro stress.

Ryningen A, Reikvam H, Nepstad I, Paulsen Rye K, Bruserud O.

 

Cancer Chemother Pharmacol. 2012 Oct 6. [Epub ahead of print]

High-dose etoposide in allogeneic stem cell transplantation.

Bruserud O, Reikvam H, Kittang AO, Ahmed AB, Tvedt TH, Sjo M, Hatfield KJ.

 

Eur J Haematol. 2012 Oct 9. doi: 10.1111/ejh.12016. [Epub ahead of print]

Soluble mediators released by acute myeloid leukemia cells increase capillary-like networks.

Hatfield KJ, Evensen L, Reikvam H, Lorens JB, Bruserud O.

 

Curr Cancer Drug Targets. 2012 Aug 2. [Epub ahead of print]

Targeted Anti-Leukemic Therapy as Disease-Stabilizing Treatment for Leukemia Relapse after Allogeneic Stem Cell Transplantation: Will It Be Possible To Combine These Strategies with Retransplantation or Donor Lymphocyte Infusions?

Reikvam H, Kittang AO, Melve G, Mosevoll KA, Bentsen PT, Ersvær E, Gjertsen BT, Bruserud O.

 

Blood. 2012 Jul 26;120(4):847-57. Epub 2012 Jun 12.

The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling.

Lång E, Grudic A, Pankiv S, Bruserud O, Simonsen A, Bjerkvig R, Bjørås M, Bøe SO.

 

Expert Opin Investig Drugs. 2012 May;21(5):587-603. Epub 2012 Mar 17.

Targeting of polo-like kinases and their cross talk with Aurora kinases - possible therapeutic strategies in human acute myeloid leukemia?

Tsykunova G, Reikvam H, Ahmed AB, Nepstad I, Gjertsen BT, Bruserud O.

 

Leukemia. 2012 Apr;26(4):563-71. doi: 10.1038/leu.2011.314. Epub 2011 Nov 11.

Venous thromboembolism in patients with essential thrombocythemia and polycythemia vera.

Reikvam H, Tiu RV.

 

Am J Hematol. 2012 Apr;87(4):368-76. doi: 10.1002/ajh.23116. Epub 2012 Feb 28.

Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment.

Fredly H, Reikvam H, Gjertsen BT, Bruserud O.

 

Br J Haematol. 2012 Feb;156(4):468-80. doi: 10.1111/j.1365-2141.2011.08960.x. Epub 2011 Dec 13.

Expression profile of heat shock proteins in acute myeloid leukaemia patients reveals a distinct signature strongly associated with FLT3 mutation status--consequences and potentials for pharmacological intervention.

Reikvam H, Hatfield KJ, Ersvaer E, Hovland R, Skavland J, Gjertsen BT, Petersen K, Bruserud O.

 

Leukemia. 2012 May;26(5):910-7. doi: 10.1038/leu.2011.315. Epub 2011 Nov 8.

Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.

McCormack E, Haaland I, Venås G, Forthun RB, Huseby S, Gausdal G, Knappskog S, Micklem DR, Lorens JB, Bruserud O, Gjertsen BT.

 

Biol Blood Marrow Transplant. 2012 Feb;18(2):190-9. doi: 10.1016/j.bbmt.2011.10.007. Epub 2011 Oct 20.

The pretransplantation serum cytokine profile in allogeneic stem cell recipients differs from healthy individuals, and various profiles are associated with different risks of posttransplantation complications.

Reikvam H, Mosevoll KA, Melve GK, Günther CC, Sjo M, Bentsen PT, Bruserud Ø.

 

Leukemia. 2012 Mar;26(3):557-9. doi: 10.1038/leu.2011.243. Epub 2011 Sep 9.

The surface molecule signature of primary human acute myeloid leukemia (AML) cells is highly associated with NPM1 mutation status.

Tsykunova G, Reikvam H, Hovland R, Bruserud Ø.

 

Oncogene. 2012 Mar 22;31(12):1533-45. doi: 10.1038/onc.2011.348. Epub 2011 Aug 22.

Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia.

Ånensen N, Hjelle SM, Van Belle W, Haaland I, Silden E, Bourdon JC, Hovland R, Taskén K, Knappskog S, Lønning PE, Bruserud Ø, Gjertsen BT.