Prevalence, phenotypes, genotypes and molecular epidemiology of ESBL-producing clinical isolates of Enterobacteriaceae in Norway

Project leader(s)   Arnfinn Sundsfjord

Co-workers / Project staff
Ståle Tofteland, Bjørg Haldorsen, Kristin H Dahl, Umaer Naseer, and Gunnar S Simonsen.

Main Objects:
We have limited knowledge regarding the prevalence and molecular epidemiology of extended spectrum betalactamase (ESBL)-producing clinical isolates of Enterobacteriaceae in Norway. Our main objectives are to: (i) Evaluate methods to detect and verify ESBL-production in Norwegian clinical isolates of Enterobacteriaceae. (ii) Fenotypic and genotypic characterization of Norwegian clinical isolates of ESBL-producing E. coli and Klebsiella pneumoniae and their molecular epidemiology.

Collaborators / Partners
Timothy Walsh, University of Bristol, UK.

Funding
University Hospital of North-Norway and the Medical Research Foundation, North-Norway

Publications
1. Tofteland S, Haldorsen B, Dahl KH, Simonsen GS, Steinbakk M, Walsh TR, Sundsfjord A and the Norwegian ESBL study group. CTX-M is the dominating extended spectrum betalactamase-type in Norwegian clinical ESBL-producing isolates of Escherichia coli and Klebsiella pneumoniae. Abstract 14th ECCMID, Praha 2004.