Contents

Vincent Eijsink: Publications in international scientific journals

Highlights before 2002

  • Structural determinants of the thermostability of thermolysin-like proteases; V.G.H. Eijsink, O.R. Veltman, W. Aukema, G. Vriend, G. Venema; Nature Struct. Biol. 2 (1995) 374-379
  • Induction of bacteriocin production in Lactobacillus sake by a secreted peptide; V.G.H. Eijsink, M.B. Brurberg, P.J. Middelhoven, I.F. Nes; J. Bacteriol. 178 (1996) 2232-2237
  • Comparative studies of chitinases A and B from Serratia marcescens; M.B. Brurberg, I.F. Nes, V.G.H. Eijsink; Microbiology 142 (1996) 1581-1589.
  • Extreme stabilization of a thermolysin-like protease by an engineered disulfide bond; J. Mansfeld, G. Vriend, B.W. Dijkstra, O.R. Veltman, B. van den Burg, G. Venema, R. Ulbrich-Hofman, V.G.H. Eijsink; J. Biol. Chem. 272 (1997) 11152-11156.
  • Pheromone-induced production of anti-microbial peptides in Lactobacillus; M.B. Brurberg, I.F. Nes, V.G.H. Eijsink; Mol. Microbiol. 26 (1997) 347-360.
  • Engineering an enzyme to resist boiling; B. van den Burg, G. Vriend, O.R. Veltman, G. Venema, V.G.H. Eijsink; Proc. Natl. Acad. Sci. USA, 95 (1998) 2056-2060
  • Early steps in the unfolding of thermolysin-like proteases; G. Vriend, H.J.C. Berendsen, B. van den Burg, G. Venema, V.G.H. Eijsink; J. Biol. Chem. 273 (1998) 35074-35077
  • Structure of a two-domain chitotriosidase from Serratia marcescens at 1.9 Å resolution; D.M.F. van Aalten, B. Synstad, M.B. Brurberg, E. Hough, B. Riise, V.G.H. Eijsink, R.K. Wierenga; Proc. Natl. Acad. Sci. USA 97 (2000) 5842-5847.
  • Functional analysis of promoters involved in quorum-sensing based regulation of bacteriocin production in Lactobacillus sake; P.A. Risøen, M.B. Brurberg, V.G.H. Eijsink, I.F. Nes; Mol. Microbiol. 37 (2000) 619-628.
  • Structural insights into the catalytic mechanism of a family 18 exochitinase; D.M.F. Van Aalten, D. Komander, B. Synstad, S. Gåseidnes, M.G. Peter, V.G.H. Eijsink; Proc. Natl. Acad. Sci. USA 98 (2001) 8979-8984

2002

  • Psammaplin A, a chitinase inhibitor isolated from Fijian Marine Sponge Aplysinella rhax; J.N. Tabudravu, V.G.H. Eijsink, G.W. Gooday, M. Jaspars, D. Komander, M. Legg, B. Synstad, D.M.F. van Aalten; Bioorg. Med. Chem. 10 (2002) 1123-1128.
  • Crystal structure of the D140N mutant of chitinase B from Serratia marcescens at 1.45 Å resolution; G. Kolstad, B. Synstad, V.G.H. Eijsink, D.M.F. Van Aalten,; Acta Crystallog. D58 (2002) 377-379.
  • The effect of modifying surface charge on the catalytic activity of a thermolysin-like protease; A. De Kreij, B. Van den Burg, G. Venema, G. Vriend, V.G.H. Eijsink, J.E. Nielsen; J. Biol. Chem. 277 (2002) 15432-15438
  • Production of class II bacteriocins by lactic acid bacteria; an example of biological warfare and communication; V.G.H. Eijsink, L. Axelsson, D.B. Diep, L.S. Håvarstein, H. Holo, I.F. Nes; Antonie van Leeuwenhoek 81 (2002) 639-654.
  • High resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors – mimicry of carbohydrate substrate; D. Houston, K. Shiomi, N. Arai, S. Omura, M.G. Peter, A. Turberg, B. Synstad, V.G.H. Eijsink, D.M.F.van Aalten; Proc. Natl. Acad. Sci. USA 99 (2002) 9127-9132.
  • Selection of mutations for increased protein stability; B. van den Burg, V.G.H. Eijsink; Curr. Opinion Biotechnol. 13 (2002) 333-337.
  • Mutational analysis of the role of tryptophane residues in an antimicrobial peptide; G. Fimland, V. G.H. Eijsink, Jon Nissen-Meyer; Biochemistry 41 (2002) 9508-9515.
  • Comparative studies of immunity proteins of pediocin-like bacteriocins; G. Fimland, V.G.H. Eijsink, J. Nissen-Meyer; Microbiology 148 (2002) 3661-3670.
  • The cyclic dipeptide CI-4 inhibits family 18 chitinases by structural mimicry of a reaction intermediate; D. Houston, I. Eggleston, B. Synstad, V.G.H. Eijsink, D.M.F. van Aalten; Biochem. J. 368 (2002) 23-27.
  • Synthesis of pseudosugar analogues of chitotriose; G. Thiele, A. Rottmann, A. Germer, E. Kleinpeter, K.-D. Spindler, B. Synstad, V. G. H. Eijsink, M. G. Peter; J. Carbohydrate Chem. 21 (2002) 471-489.

2003

  • Rational engineering of the stability and the catalytic performance of enzymes; S. Gåseidnes, B. Synstad, J.E. Nielsen, V.G.H. Eijsink; J. Molecular Catalysis, B: Enzymatic 21 (2003) 3-8.
  • A network of salt bridges contributes to the pH-dependent stability and oligomerization state of a tetrameric malate dehydrogenase; A. Bjørk, D. Mantzilas, R. Sirevåg, V.G.H. Eijsink; FEBS letters 553 (2003) 423-426.
  • Stabilization of a chitinase from Serratia marcescens by Gly -> Ala and Xxx -> Pro mutations; S. Gåseidnes, B. Synstad, X. Jia, H. Kjellesvik, G. Vriend, V.G.H. Eijsink; Protein Engineering 16 (2003) 841-846.
  • Stabilization of a Tetrameric Malate Dehydrogenase by Introduction of a Disulfide Bridge at the Dimer-Dimer Interface; A. Bjørk, B. Dalhus, D. Mantzilas, V.G.H. Eijsink, R. Sirevåg; J. Mol. Biol. 334 (2003) 811-821.
  • Genetic dissection of a composite bacteriocin locus from malt isolate Lactobacillus sakei 5; A. Vaughan, V.G.H. Eijsink, D. van Sinderen; Appl. Environm. Microbiol. 69 (2003) 7194-7203.
  • Construction of vectors for inducible gene expression in Lactobacillus sakei and L. plantarum; E. Sørvig, S. Grönqvist, K. Naterstad, G. Mathiesen, V.G.H. Eijsink, L. Axelsson; FEMS Microbiol. Lett. 229 (2003) 119-126.

2004

  • Structure of the D142N mutant of the family 18 chitinase ChiB from Serratia marcescens and its complex with allosamidin; G. Vaaje-Kolstad D.R. Houston, F.V. Rao, M.G. Peter, B. Synstad, D.M.F. van Aalten, V.G.H. Eijsink; Biochim. Biophys. Acta 1696 (2004) 103-111.
  • Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono-delta-lactone; G. Vaaje-Kolstad, A. Vasella, M.G. Peter, C. Netter, D.R. Houston, B. Westereng, B. Synstad, V.G.H. Eijsink, D.M.F. van Aalten; J. Biol. Chem. 279 (2004) 3612-3619.
  • Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase; B. Synstad, S. Gåseidnes, D.M.F. van Aalten, G. Vriend, J.E.Nielsen, V.G.H. Eijsink; Eur. J. Biochem. 271 (2004) 253-262.
  • A reliable reducing end assay for chito-oligosaccharides; S.J. Horn, V.G.H. Eijsink; Carbohydrate Polymers 56 (2004) 35-39.
  • Use of bacteriocin promoters for gene expression in Lactobacillus plantarum C11; G. Mathiesen, H.M. Namløs, P.A. Risøen, L. Axelsson, V.G.H. Eijsink; Journal of Applied Microbiology 96 (2004) 819-827.
  • Transcriptional control of bacteriocin production by malt isolate Lactobacillus sakei 5; A.. Vaughan, J. O’ Mahony, V.G.H. Eijsink , M. O’ Connell-Motherway, D. van Sinderen; FEMS Microbiol Lett. 235 (2004) 377-384.
  • High-level gene expression in Lactobacillus plantarum using a pheromone-regulated bacteriocin promoter; G. Mathiesen, E. Sørvig, J. Blatny, K. Naterstad, L. Axelsson, V.G.H. Eijsink; Letters Appl. Microbiol. 39 (2004) 137-143.
  • 123I-Labeled Chitinase as Specific Radioligand for In Vivo Detection of Fungal Infections in Mice; R. Siaens, V.G.H. Eijsink, R. Dierckx, G. Slegers; J. of Nuclear Medicine 45 (2004) 1209-1216.
  • Rational engineering of enzyme stability; V.G.H. Eijsink, S. Gåseidnes, B. Synstad, A. Bjørk, R. Sirevåg, B. Van den Burg, G. Vriend, G.; J. Biotechnol. 113 (2004) 105-120.
  • Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface; A. Bjørk, B. Dalhus, D. Mantzilas, R. Sirevåg, V.G.H. Eijsink; J. Mol. Biol. 341 (2004) 1215-1226.
  • Structure-based optimization of a family 18 chitinase cyclic dipeptide inhibitor; D.R. Houston, B. Synstad, V.G.H. Eijsink, I. Eggleston, D.M.F. van Aalten; J. Med. Chem. 47 (2004) 5713-5720.

2005

  • Enzymatic hydrolysis of Atlantic cod (Gadus morhua L.) viscera; Aspmo, S.I., Horn, S.J., Eijsink, V.G.H., Process Biochem. 40 (2005) 1957-1966.
  • Degradation of chitosans with Chitinase B from Serratia marcescens; production of chito-oligosaccharides and insight in enzyme processivity; A. Sørbotten, S.J. Horn, V.G.H. Eijsink, K.M. Vårum; FEBS J. 272 (2005) 1523-1534.
  • Plasmid p256 from Lactobacillus plantarum represents a new type of replicon in lactic acid bacteria and contains a toxin-antitoxin plasmid maintenance system; E. Sørvig, M. Skaugen, K. Naterstad, V.G.H. Eijsink, L. Axelsson; Microbiology 151 (2005) 421-431.
  • Crystal structure and binding properties of the chitin-binding protein from Serratia marcescens; G. Vaaje-Kolstad, D.R. Houston, V.G.H. Eijsink, D.M.F. van Aalten; J. Biol. Chem. 280 (2005) 11313-11319.
  • Development and application of a model for chitosan hydrolysis by a family 18 chitinase; P. Sikorski, B.T. Stokke, A. Sørbotten, K.M. Vårum, S.J. Horn, V.G.H. Eijsink; Biopolymers 77 (2005) 273-285.
  • Overexpression and characterisation of a new chitinase from Trichoderma atroviride strain P1; I. A. Hoell, S. S. Klemsdal, G. Vaaje-Kolstad, S. J. Horn, V.G.H. Eijsink, Biochim. Biophys. Acta 1748 (2005) 180-190.
  • Characterization of a new bacteriocin operon in Sakacin P- producing lactobacillus sakei showing strong translational coupling between the bacteriocin and immunity genes; G. Mathiesen, K. Hühne, K. Naterstad, L. Kröckel, L. Axelsson, V.G.H. Eijsink; Appl. Environm. Microbiol. 71 (2005) 3565-3574.
  • B. van den Burg, S. Gåseidnes, T.V. Borchert, V.G.H. Eijsink; Directed Evolution of Enzyme Stability; Biomolecular Engineering 22 (2005) 21-30.
  • High-level, inducible gene expression in Lactobacillus sakei and L. plantarum using optimized expression vectors; E. Sørvig; G. Mathiesen, K. Naterstad, V.G.H. Eijsink, L. Axelsson; Microbiology 151 (2005) 2439-2449.
  • Hydrolysates from atlantic cod (Gadus morhua L.) viscera as components of microbial growth media. S.I. Aspmo, S.J. Horn, V.G.H. Eijsink; Process Biochem. 40 (2005) 3714-3722.
  • Use of hydrolysates from Atlantic cod (Gadus morhua L.) viscera as a complex nitrogen source for lactic acid bacteria. S.I. Aspmo, S.J. Horn, V.G.H. Eijsink; FEMS Microbiol. Lett. 248(2005) 65-68.
  • Growth of Lactobacillus plantarum in media containing hydrolysates of fish viscera. S.J. Horn, S.I. Aspmo, V.G.H. Eijsink; J. Appl. Microbiol. 99 (2005) 1082-1089.
  • The non-catalytic chitin-binding protein CBP21 from Serratia marcescens is essential for chitin degradation. G. Vaaje-Kolstad, S.J. Horn, D.M.F. Van Aalten, B. Synstad, V.G.H. Eijsink. J. Biol. Chem. 280 (2005) 28492-28497 (Paper of the week)
  • Bacterial lessons in sausage making. V.G.H. Eijsink, L: Axelsson, Nature Biotechnol. 23 (2005) 1494-1495.

2006

  • Comparative studies of chitinases A, B, and C from Serratia marcescens. S.J. Horn, M. Sørlie, A.L. Norberg, B. Synstad, G. Vaaje-Kolstad, K.M. Vårum, V.G.H. Eijsink; Biocatalysis and Biotransformation, 24 (2006) 39-53.
  • In vitro evolution of a subfamily 10 histidine protein kinase (SppK) from Lactobacillus. G. Mathiesen, G.W. Axelssen, L. Axelsson, V.G.H. Eijsink; Arch. Microbiol. 184 (2006) 327-334.
  • Endo/exo mechanism and processivity of family 18 chitinases produced by Serratia marcescens. S.J. Horn, A. Sørbotten, B. Synstad, P. Sikorski, M. Sørlie, K.M. Vårum, V.G.H. Eijsink; FEBS J. 273 (2006) 491-503.
  • Identification of non-covalent glycosidase chitooligosaccharide complexes by (+) nanoelectrospray quadrupole time-of-flight mass spectrometry. F.C. Cederkvist, A. Zamfir, V.G.H. Eijsink, M. Sørlie, J. Peter-Katalinic, M.G. Peter; Ang Chemie Int Ed. 45(2006) 2429-2434
  • Molecular cloning, characterization, and real-time expression studies of a novel endochitinase gene (ech30) from the mycoparasite Trichoderma atroviride strain P1. S.S. Klemsdal, J.L. Clarke, I.A. Hoell, V.G.H. Eijsink, M.B. Brurberg; FEMS Microbiol. Lett. 256(2006) 282-289.
  • Synthesis and evaluation of a 99mTc-HYNIC-labeled chitin-binding protein as potential specific radioligand for the in vivo detection of fungal infections in mice. R. Siaens, V.G.H. Eijsink, G. Vaaje-Kolstad, K. Vandenbulcke, B. Cornelissen, R. Dierckx, G. Slegers, Quart. J. Nucl. Medic. Mol. Imaging 50 (2006)155-166.
  • Serratia marcescens chitinases with “tunnel-shaped” substrate-binding grooves show endo-activity and different degrees of processivity during enzymatic hydrolysis of chitosan; P. Sikorski, A. Sørbotten, S. J. Horn, V. G. H. Eijsink, K. M. Vårum; Biochemistry, 45(2006) 9566-9574.
  • Purification, characterization and gene sequence of michiganin type B lantibiotic produced by the tomato pathogen Clavibacter michiganensis subsp. michiganensis; I. Holtsmark, D. Mantzilas, V.G.H. Eijsink, M.B. Brurberg; Appl. Environm. Microbiol. 72(2006) 5814-5821.
  • Crystal structure and enzymatic properties of a bacterial family 19 chitinase reveal differences with plant enzymes; I.A. Hoell, B. Dalhus, E.B. Heggset, S.I. Aspmo, V.G.H. Eijsink; FEBS J. 273 (2006) 4889-4900.
  • Enzymatic degradation of recalcitrant polysaccharides: costs and benefits of processivity S.J. Horn, P. Sikorski, J.B. Cederkvist, G. Vaaje-Kolstad, M. Sørlie, B. Synstad, G. Vriend, K.M. Vårum, V.G.H. Eijsink; Proc. Natl. Acad. Sci. USA 103(2006) 18089-18094.

2007

  • The tomato pathogen Clavibacter michiganensis subsp. michiganensis: producer of a broad spectre of antimicrobial substances; I. Holtsmark, D. Mantzilas, V.G.H. Eijsink, M.B. Brurberg; J. Appl. Microbiol., in press.
  • Evaluation of seasonal variation in cod viscera hydrolysates used in a growth medium for lactic acid bacteria. S.J. Horn, S.I. Aspmo, V.G.H. Eijsink. Enzyme Micr. Technol., in press.
  • Natural Substrate Assay for Chitinases Using High Performance Liquid Chromatography: A Comparison with Existing Assays; I.M. Krokeide, B. Synstad, S. Gåseidnes, S. J. Horn, V.G.H. Eijsink, M. Sørlie. Anal. Biochem., in press.
  • Precise and Continuous Enzyme Assay for Chitinase Catalyzed Hydrolysis of Tetra-N-acetylchitotetraose Using Isothermal Titration Calorimetry. I.-M. Krokeide, V.G.H. Eijsink, M. Sørlie. Thermochimica Acta, in press.
  • Mucolytic activity of bacterial and human chitinases. N. N. Sanders, V.G.H. Eijsink, P.S. van den Pangaart, R.J. van Neerven, P.J. Simons, S.C. De Smedt, J. Demeester, Biochim. Biophys. Acta, submitted for publication, November 2006.


Last updated: 2007-01-08